Home / Medical Devices / Bone Grafts And Substitutes Market By Application (Spinal Fusion, Long Bone, Foot And Ankle, Craniomaxillofacial, Joint Reconstruction, Dental), By Material (Bone Grafts Substitutes, Allografts) - Growth, Future Prospects, And Competitive Analysis, 2017 - 2025

Bone Grafts And Substitutes Market By Application (Spinal Fusion, Long Bone, Foot And Ankle, Craniomaxillofacial, Joint Reconstruction, Dental), By Material (Bone Grafts Substitutes, Allografts) - Growth, Future Prospects, And Competitive Analysis, 2017 - 2025

Published: Nov 2017 | Report Code: 58802-11-17

This report on global bone grafts and substitutes studies the market in terms of various materials and applications. The market is driven by key factors such as increase in the number of traumatic injuries, rising geriatric population suffering with osteoporosis, rheumatoid arthritis and periodontal diseases. Additionally the increasing number of minimally invasive surgeries performed for complications such disc herniation, burst fractures etc. will have a positive influence on the growth of bone grafts and substitutes products. The limiting factors related to this market are the immune response generated during surgical procedures, post-operative pain and stringent regulatory guidelines regarding the approval of the bone grafts and substitutes.

For the purpose of this study, the various materials studied are bone graft substitutes and allografts. Bone graft substitutes are further categorized into bone morphogenic proteins, synthetic bone grafts and others. Allografts are further sub-segmented as demineralized bone matrix and others. Applications studied for the purpose of this research includes spinal fusion, long bone, foot and ankle, craniomaxilofacial, joint reconstruction and dental. Market size estimates and forecast for these segments for the period 2015 to 2025 are provided in terms of US$ Mn along with the respective CAGRs for the period 2017 to 2025, considering 2016 as the base year.

Geographic segmentation of the global bone grafts and substitutes market is performed for the regions North America, Europe, Asia Pacific, Latin America and Middle East and Africa. The regions are also further sub-segmented on the basis of major countries:

  • North America
    • U.S.
    • Canada
  • Europe
    • U.K.
    • Germany
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • Rest of Asia Pacific
  • Latin America
    • Mexico
    • Brazil
    • Rest of LATAM
  • Middle East and Africa
    • GCC
    • Rest of Middle East and Africa

Market size estimates and forecast for these segments for the period 2015 to 2025 are provided in terms of US$ Mn along with the respective CAGRs for the period 2017 to 2025, considering 2016 as the base year.

This report also includes qualitative assessment factors such as market dynamics (drivers, restraints and opportunities) to have a good understanding of the current and anticipated trends in the global bone grafts and substitutes market. Market attractiveness assessment, Porter’s five forces model and competitive landscape analysis by key players are also presented in the study. Furthermore, this report concludes with profiling of key market players currently enjoying prominent position in the global bone grafts and substitutes market. The major players in global bone grafts and substitutes market are AlloSource, Baxter Healthcare Corporation, DePuy Synthes, Medtronic plc, NuVasive, Inc., Orthofix Holdings, Inc., Orthovita, Inc., Stryker Corporation, Smith & Nephew, Inc. and Wright Medical Group N.V.

Bone Grafts And Substitutes Market

Chapter 1. Preface
1.1. Report Scope and Description
1.2. Research Methodology
1.2.1. Phase I-Secondary Research
1.2.2. Phase II-Primary Research
1.2.3. Phase III-Expert Panel Review
1.2.4. Assumptions
1.2.5. Approach Adopted

Chapter 2. Executive Summary
2.1. Global Bone Grafts and Substitutes Market Portraiture
2.1.1. Global Bone Grafts and Substitutes Market, by Material, 2016
2.1.2. Global Bone Grafts and Substitutes Market, by Application, 2016
2.1.3. Global Bone Grafts and Substitutes Market, by Geography, 2016

Chapter 3. Bone Grafts and Substitutes Market: Dynamics and Future Outlook
3.1. Market Overview
3.2. Drivers
3.3. Challenges
3.4. Opportunities
3.5. Porter’s Five Forces Analysis
3.6. Attractive Investment Proposition, by Geography
3.7. Top 3 Countries: Global Bone Graft and Substitutes Market, 2015-2025 (US$ Mn)
3.8. Competitive Landscape: Global Bone Graft and Substitutes Market, 2017

Chapter 4. Global Bone Grafts and Substitutes Market, by Material, 2015 – 2025 (US$ Mn)
4.1. Overview
4.2. Attractive Investment Proposition: Global Bone Grafts and Substitutes Market, by Material, 2016
4.3. Bone Grafts Substitutes
4.3.1. Bone Morphogenic Proteins (BMP)
4.3.2. Synthetic Bone Grafts
4.3.3. Others
4.4. Allografts
4.4.1. Demineralized Bone Matrix
4.4.2. Others

Chapter 5. Global Bone Grafts and Substitutes Market, by Application, 2015 – 2025 (US$ Mn)
5.1. Overview
5.1.1. Attractive Investment Proposition: Global Bone Grafts and Substitutes Market, by Application, 2016
5.2. Spinal Fusion
5.3. Long Bone
5.4. Foot and Ankle
5.5. Craniomaxillofacial
5.6. Joint Reconstruction
5.7. Dental

Chapter 6. Global Bone Grafts and Substitutes Market, by Geography, 2015 – 2025 (US$ Mn)
6.1. Overview
6.2. North America Bone Grafts and Substitutes Market Analysis, 2015 – 2025
6.2.1. North America Bone Grafts and Substitutes Market, by Material, 2015 – 2025 (US$ Mn)
6.2.2. North America Bone Grafts and Substitutes Market, by Application, 2015 – 2025 (US$ Mn)
6.2.3. North America Bone Grafts and Substitutes Market, by Country, 2015 – 2025 (US$ Mn)
6.2.3.1. U.S.
6.2.3.2. Canada
6.3. Europe Bone Grafts and Substitutes Market Analysis, 2015 – 2025
6.3.1. Europe Bone Grafts and Substitutes Market, by Material, 2015 – 2025 (US$ Mn)
6.3.2. Europe Bone Grafts and Substitutes Market, by Application, 2015 – 2025 (US$ Mn)
6.3.3. Europe Bone Grafts and Substitutes Market, by Country, 2015 – 2025 (US$ Mn)
6.3.3.1. U.K.
6.3.3.2. Germany
6.3.3.3. Rest of Europe
6.4. Asia Pacific Bone Grafts and Substitutes Market Analysis, 2015 – 2025
6.4.1. Asia Pacific Bone Grafts and Substitutes Market, by Material, 2015 – 2025 (US$ Mn)
6.4.2. Asia Pacific Bone Grafts and Substitutes Market, by Application, 2015 – 2025 (US$ Mn)
6.4.3. Asia Pacific Bone Grafts and Substitutes Market, by Country, 2015 – 2025 (US$ Mn)
6.4.3.1. Japan
6.4.3.2. China
6.4.3.3. India
6.4.3.4. Rest of APAC
6.5. Latin America Bone Grafts and Substitutes Market Analysis, 2015 – 2025
6.5.1. Latin America Bone Grafts and Substitutes Market, by Material, 2015 – 2025 (US$ Mn)
6.5.2. Latin America Bone Grafts and Substitutes Market, by Application, 2015 – 2025 (US$ Mn)
6.5.3. Latin America Bone Grafts and Substitutes Market, by Country, 2015 – 2025 (US$ Mn)
6.5.3.1. Brazil
6.5.3.2. Mexico
6.5.3.3. Rest of Latin America
6.6. Middle East & Africa (MEA) Bone Grafts and Substitutes Market Analysis, 2015 – 2025
6.6.1. MEA Bone Grafts and Substitutes Market, by Material, 2015 – 2025 (US$ Mn)
6.6.2. MEA Bone Grafts and Substitutes Market, by Application, 2015 – 2025 (US$ Mn)
6.6.3. MEA Bone Grafts and Substitutes Market, by Region, 2015 – 2025 (US$ Mn)
6.6.3.1. GCC
6.6.3.2. Rest of MEA

Chapter 7. Company Profiles
7.1. AlloSource
7.1.1. Business Description
7.1.2. Financial Information (Subject to data availability)
7.1.3. Product Portfolio
7.1.4. Key Developments
7.2. Baxter Healthcare Corporation
7.3. DePuy Synthes
7.4. Medtronic plc
7.5. NuVasive, Inc.
7.6. Orthofix Holdings, Inc.
7.7. Orthovita, Inc.
7.8. Stryker Corporation
7.9. Smith & Nephew, Inc.
7.10. Wright Medical Group N.V.

List of Tables :

TABLE 1 Global Bone Grafts and Substitutes Market Portraiture
TABLE 2 Global Bone Grafts and Substitutes Market, by Material, 2015 – 2025 (US$ Mn)
TABLE 3 Global Bone Graft Substitutes Material Market, by Type 2015 – 2025 (US$ Mn)
TABLE 4 Global Allografts Market for Bone Grafts and Substitutes, by Type, 2015 – 2025 (US$ Mn)
TABLE 5 Global Bone Grafts and Substitutes Market, by Application, 2015 – 2025 (US$ Mn)
TABLE 6 Global Bone Grafts and Substitutes Market, by Geography, 2015 – 2025 (US$ Mn)
TABLE 7 North America Bone Grafts and Substitutes Market, by Material, 2015 – 2025 (US$ Mn)
TABLE 8 North America Bone Grafts and Substitutes Market, by Application, 2015 – 2025 (US$ Mn)
TABLE 9 North America Bone Grafts and Substitutes Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 10 Europe Bone Grafts and Substitutes Market, by Material, 2015 – 2025 (US$ Mn)
TABLE 11 Europe Bone Grafts and Substitutes Market, by Application, 2015 – 2025 (US$ Mn)
TABLE 12 Europe Bone Grafts and Substitutes Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 13 Asia Pacific Bone Grafts and Substitutes Market, by Material, 2015 – 2025 (US$ Mn)
TABLE 14 Asia Pacific Bone Grafts and Substitutes Market, by Application, 2015 – 2025 (US$ Mn)
TABLE 15 Asia Pacific Bone Grafts and Substitutes Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 16 Latin America Bone Grafts and Substitutes Market, by Material, 2015 – 2025 (US$ Mn)
TABLE 17 Latin America Bone Grafts and Substitutes Market, by Application, 2015 – 2025 (US$ Mn)
TABLE 18 Latin America Bone Grafts and Substitutes Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 19 Middle East and Africa Bone Grafts and Substitutes Market, by Material, 2015 – 2025 (US$ Mn)
TABLE 20 Middle East and Africa Bone Grafts and Substitutes Market, by Application, 2015 – 2025 (US$ Mn)
TABLE 21 Middle East and Africa Bone Grafts and Substitutes Market, by Region, 2015 – 2025 (US$ Mn)
TABLE 22 AlloSource: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 23 Baxter Healthcare Corporation: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 24 DePuy Synthes: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 25 Medtronic plc: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 26 NuVasive, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 27 Orthofix Holdings, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 28 Orthovita, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 29 Stryker Corporation: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 30 Smith & Nephew, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 31 Wright Medical Group N.V.: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)

List of Figures :

FIG. 1 Bone Grafts and Substitutes: Market Segmentation
FIG. 2 Global Bone Grafts and Substitutes Market Share, by Material, 2016 (Value %)
FIG. 3 Global Bone Grafts and Substitutes Market, by Application, 2016 (Value %)
FIG. 4 Global Bone Grafts and Substitutes Market Share, by Geography, 2016 (Value %)
FIG. 5 Attractive Investment Proposition, by Geography
FIG. 6 Market Competition Landscape, by Key Players, 2016
FIG. 7 Global Bone Morphogenic Proteins Market, 2015 – 2025 (US$ Mn)
FIG. 8 Global Synthetic Bone Grafts Market, 2015 – 2025 (US$ Mn)
FIG. 9 Global Other Bone Graft Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 10 Global Demineralized Bone Matrix Market, 2015 – 2025 (US$ Mn)
FIG. 11 Global Other Allografts Market, 2015 – 2025 (US$ Mn)
FIG. 12 Global Spinal Fusion Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 13 Global Long Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 14 Global Foot and Ankle Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 15 Global Craniomaxillofacial Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 16 Global Joint Reconstruction Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 17 Global Dental Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 18 U.S. Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 19 Canada Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 20 U.K. Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 21 Germany Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 22 Rest of Europe Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 23 Japan Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 24 China Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 25 India Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 26 Rest of Asia Pacific Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 27 Brazil Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 28 Mexico Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 29 Rest of Latin America Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 30 GCC Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)
FIG. 31 Rest of Middle East and Africa Bone Grafts and Substitutes Market, 2015 – 2025 (US$ Mn)

Based on application, the bone graft and substitutes market is categorized into

  • Spinal Fusion
  • Long Bone
  • Foot and Ankle
  • Craniomaxilofacial
  • Joint Reconstruction
  • Dental

Bone Grafts And Substitutes Market

The ideal bone graft substitutes should consists of the following essential features such as osteoconductive matrix, osteoinductive properties and osteogenic cells. Autogenous cancellous bone grafting has been considered as the gold standard in bone transplantation, but the limitations imposed were enhanced operative blood loss, donor site morbidity and limited availability for harvest. Spinal fusion provides a lucrative market and dominates the market share due to factors such as rising prevalence of low spine disc herniation, burst fractures, osteoporosis etc. and increasing number of patients suffering with cauda equine syndrome are preferring spinal fusion surgeries to release pressure on many spinal nerves, which causes paralysis in lower extremities. Dental surgeries are anticipated to be the fastest growing market majorly due to factors such as rising prevalence of periodontal disease, vehicular accidents resulting dental trauma resulting in loss of teeth and gum causing deformation in outward cosmetic appearance and dental bone grafting is also employed to maintain bone structure after tooth extraction. Dental implants also impart other benefits such as improved speech, convenience during eating and improved oral health.

For the purpose of this study, the global bone grafts and substitutes market is categorized into the following regional and country specific markets:

  • North America
    • U.S.
    • Canada
  • Europe
    • U.K.
    • Germany
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East and Africa
    • GCC
    • Rest of Middle East and Africa

Bone Grafts And Substitutes Market

North America was observed to be the largest bone grafts and substitutes market in the base year 2016. According to the Centers for Disease Control and Prevention 2013-14 survey, the prevalence of osteoporosis in U.S. were 5.1% for men over 65 years of age and 24.5 % for women. The dominance of North America is mainly attributed to the presence of key drivers such as rising prevalence of traumatic accidents, osteoporosis, existence of developed healthcare infrastructure with orthopedic facility and domicile of key players pioneering in manufacture of bone grafts and substitutes. The market growth in Europe is mainly attributed to increase in the number of geriatric patients suffering with osteoporosis and periodontal diseases and presence of manufacturers focusing on the research and development activities required to produce next generation of bone grafts and substitutes. Asia Pacific is observed to be the fastest growing regional segment throughout the forecast period 2017-2025. Factors that are anticipated to propel the market growth in Asia Pacific are the increasing number of traumatic injuries inflicted due to car accidents, violence and sports injuries requiring surgical procedures, increasing disposable incomes makes it feasible to avail for healthcare services, flourishing e-commerce industry to promote sales and supportive regulatory environment for bone grafts and substitutes. Moreover, factors such as developing healthcare infrastructure, health awareness campaigns to promote sales and establishment of subsidiaries by major players in the untapped markets are going to fuel the rapid growth of bone grafts and substitutes market in Latin America, and Middle East and Africa in the near future.   

Based on material, the global bone grafts and substitutes market is categorized into:

  • Bone Grafts Substitutes
    • Bone Morphogenic Proteins (BMP)
    • Synthetic Bone Grafts
    • Others
  • Allografts
    • Demineralized Bone Matrix
    • Others

Bone Grafts And Substitutes Market

The bone grafts and substitutes market is driven by key factors such as rising prevalence of lumbar spine trauma, joint trauma and craniomaxillofacial surgeries required due to increase in road accidents, sports injuries, workplace injuries, falls and violence, increasing geriatric population with joint disorders and increasing number of minimally invasive procedures. Manufacturers involved in the production of bone grafts and substitutes are intensively focusing on imparting aesthetic values to their products such as distinctive and versatile handling features that helps the surgeon techniques. Presently, allografts hold the largest market share due to key drivers such as rising prevalence of traumatic bone injuries such as spine, hips, knees etc., cost efficient procedures due to smaller hospital stay, quick surgical procedure and early wound recovery period. Bone graft substitutes show a promising sales forecast and will be the fastest growing segment majorly due to factors such as accelerated bone formation due to inherent features of bone substitutes such as negative surface charge, increased protein fusion, enhanced cell attachment and favorable natural remodeling and graft resorption. The major players in bone grafts and substitutes market are AlloSource, Baxter Healthcare Corporation, DePuy Synthes, Medtronic plc, NuVasive, Inc., Orthofix Holdings, Inc., Orthovita, Inc., Stryker Corporation, Smith & Nephew, Inc. and Wright Medical Group N.V.

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