Celiac Disease: Overview
Celiac disease (CD) is a digestive illness that usually affects the small intestine of the human body. It’s a complicated immunological-mediated disorder in which the immune system damages the small bowel when persons with the condition eat gluten. Blood tests reveal specific indicators that aid in diagnosis confirmation. Gluten attacks the immune system and further damages the small intestine in people with celiac disease. When this happens, your body cannot absorb or obtain the essential nutrients.
Women are diagnosed with CD at a higher rate than men, with a female-to-male ratio ranging from 2:1 to 3:1. Except for places with a low frequency of CD-predisposing genes and low gluten consumption, the CD is one of the most common autoimmune illnesses, with a reported prevalence of 0.5–1% of the general population. In addition, pregnant women afflicted by the condition who suffer from vitamin deficiencies are more likely to give birth to babies with congenital disabilities.
Report Key Takeaways
Recommended Medications/Treatments for Celiac Disease
- Many of the symptoms of the disease can be avoided or treated by consuming a gluten-free diet. People having celiac disease require to see healthcare experts regularly. They also need to stick to the given diet for the rest of their life. Even a tiny amount of gluten can cause damage to your intestine and cause the condition to resurface.
- The patient can still eat a well-balanced diet if they have celiac disease. Gluten-free bread and items are available from several food firms and supermarket stores. Patients with celiac disease can also eat gluten-free fresh food products that are natural and made without any artificial process.
Recent Developments Related to Celiac Disease
- The FDA has released new guidance for medication developers targeting the development of more recent supplements as a part of the gluten-free diet for adults with celiac disease. This new guidance is primarily meant to clarify current standards clearly and needs to be treated as recommendations, according to the agency.
- According to experts, a major observational cohort study conducted in Copenhagen proved that malabsorption is linked to celiac disease. This latest research study has discovered many biochemical abnormalities related to celiac disease antibody positivity in a primary care environment.
- A new study led by the University of Bristol which was funded National Institute for Health indicated that targeted testing of people with various indications and symptoms could improve celiac disease diagnosis. This study aimed to determine which signs suggest a higher risk of celiac disease and, as a result, which should be tested further.
Major Players Working on Celiac Disease
Prominent companies working on the research and development for the drug/treatment development for celiac disease include Anokion, Amyra biotech, Allero Therapeutics, Millennium Pharmaceuticals, ActoBio Therapeutics, 9 Metres Biopharma, and ImmusanT.
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