Heart Failure- Pipeline Insights, Recent Developments, Major Players and Review

Heart Failure: Overview

Heart failure occurs when the heart is unable to pump blood at a rate that is sufficient to fulfil the needs of the metabolizing tissues. The heart's pumping motion is primarily responsible for promptly delivering oxygen and nutrient-rich blood to all the cells of the body. The human body can perform its normal functions when all the cells in the body get proper nourishment. The weaker heart can't give enough blood to the cells in heart failure.

Heart failure affects almost 64.3 million individuals across the globe. The prevalence of recognized heart failure is believed to be between 1% and 2% of the overall adult population in affluent countries. Heart failure is considered a critical medical condition that generally doesn’t have a complete cure. When heart failure is treated with drugs and healthy lifestyle adjustments, many people with the illness can live a joyful life.

Report Key Takeaways

Recommended Medications for Heart Failure

Healthcare experts usually recommend a combination of medications for patients to ensure the proper treatment of heart failure. As per the symptoms observed in the patient, following one or more medications can be recommended.

  • Beta blockers: These medications lower blood pressure and lower heart rate. It is quite effective and it also allows you healthy life by largely reducing the symptoms and signs of heart failure and boosting the overall heart function.
  • Positive inotropes: People in the hospital with certain types of severe heart failure may get these drugs by IV. Positive inotropes can aid in the efficient pumping of blood and the maintenance of blood pressure.
  • Diuretics: Diuretics, often known as water tablets, cause you to urinate more regularly and prevent fluid from building up in your body. Diuretics, such as furosemide, help in reducing the fluid level in the lungs, thereby making it easier for a human to breathe comfortably.
  • Vericiguat: These are the newly developed medications that are proving effective for treating heart failure. An oral soluble stimulator called guanylate cyclase is such sort of medicine and it’s taken by mouth once a day. People with high-risk heart failure who took vericiguat had fewer heart failure hospital stays, according to research.

Recent Developments Related to Heart Failure

  • According to a new study, an Apple Watch app could help diagnose left-ventricular malfunction. A left-ventricular dysfunction is a type of disorder that usually occurs when the heart fails to pump effectively. The app performed comparably to a typical 12-lead EKG in the trial. According to experts, this could allow individuals to detect and monitor heart failure without having to contact their doctor.
  • As per the latest findings of a Phase 3 clinical trial, sacubitril-valsartan, a combination oral treatment, can effectively reduce pulmonary blood pressure. This licensed treatment can be helpful for people with pulmonary hypertension (PH) associated with heart failure.
  • The findings of the EMPRISE real-world study, which studied Jardiance's first five years of use in the United States, add to previous findings from the landmark EMPA-REG OUTCOME® trial. I have shown Jardiance reduced hospitalization for heart failure by 35% compared to placebo in adults with type 2 diabetes and established cardiovascular disease.

Major Players Working on Heart Failure

AstraZeneca, Heartseed Inc., Abbott Laboratories, Bristol Myers Squibb, Cardiora, Sardocor Corp., Bayer HealthCare, and Palatin Technologies are among the leading companies working on developing effective solutions for the heart failure.

Key Reasons to Purchase This Report

  • The pipeline insights features heart failure medications with comprehensive coverage of latest developments with regards to strategic collaborations, advance technology, and licensing.
  • A detailed coverage of recent clinical studies, R&D activities, new drug approvals, and investments, other product related developments.
  • Insights on companies working closely to develop newer solutions to overcome the limitations of existing medications.

The individual will feel shortness of breath while doing activity as there will not be an enough oxygen for heart to function normally. Fluid build-up can leads to swollen feet, ankles, stomach, and lower back areas.

A heart attack, heart valve disease, high blood pressure, and cardiomyopathy are some of the medical conditions that causes heart failure.

At the time of initial examination, the concerned doctor will inquire all detail about the previous medical history, list down the current symptoms, and then perform a complete physical examination. After the initial examination, you will sent for the one or couple of tests such as: echocardiogram, blood test, electrocardiogram, and chest X-ray.

Although there is no cure for heart failure, the medications available can help people manage their symptoms, allowing them to live full and active lives. Some of the treatments are: pacemaker, medication, or coronary bypass surgery.

Heart failure is commonly observed in people above 65 years of age and women population.

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Published Date:  Jun 2022
Category:  Medical Devices
Report ID:   60557
Report Format:   PDF
Pages:   90
Rating:    4.7 (15)
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