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Cell Culture Monitoring Biosensors Market By Electrode (Electrochemical, Thermometric, Optical, Piezoelectric), By Analyte (Atp, Adenosine, Hypoxanthine, Glutamate, Glucose, Lactate), By End User (Pharmaceutical Industry, Research Labs, Food & Beverages) - Growth, Future Prospects & Competitive Analysis, 2017 – 2025

Cell cultures are an important and fundamental tool essential for the development of target-based therapies such as biosimilars, biologics, and personalized medicine. The current trend for developing medication is making it more patient-centric, so personalized medicines are in greater demand for treating various chronic conditions and orphan indications. The development of target-based therapies for the above-mentioned conditions requires that they be carried out at a faster pace with no scope for errors during the development stages. Cell culture monitoring biosensors enable minimizing the risks associated with cell culture by providing information pertaining to changes in temperature, the release of toxic substances, the formation of a predetermined metabolite, and an increase in cell density. These changes, when monitored manually, could lead to increased risk of contamination, reading errors, difficulty in scaling up samples for molecule development, and loss of time, money, and cell samples. Thus, the increase in the development of target-based therapies fuels the need for cell culture monitoring biosensors.

The current study report on cell culture monitoring biosensors encompasses a complete understanding of the current market trends and dynamics across the duration of 2015–2025. The report elaborates on market strategies and conducts a thorough analysis of the current market scenario and future trends for the period 2017-2025.

The global cell culture monitoring biosensors market has been studied by bifurcating the market based on the various electrodes utilized in the biosensors, the varied analytes that could be detected using the biosensors, and their application across various industries.

The cell culture monitoring biosensors market segmentation is as follows:

Electrode

  • Electrochemical
  • Thermometric
  • Optical
  • Piezoelectric

Analyte

  • ATP
  • Adenosine
  • Hypoxanthine
  • Glutamate
  • Glucose
  • Lactate
  • Others (Ionosine, Acetylcholine, Choline, & D-Serine)

End User

  • Pharmaceutical Industry
  • Research labs
  • Food & Beverages

The current report also provides an outlook for cell culture monitoring biosensors across geographies, which are as follows:

  • North America
    • U.S.
    • Canada
  • Europe
    • U.K
    • Germany
    • Rest of Europe
  • Asia Pacific
    • Japan
    • China
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • rest of Latin America
  • Middle East and Africa (MEA)
    • GCC
    • the remainder of MEA

The current report incorporates market estimation and forecast evaluation for the aforementioned segments for the period 2015-2025, which are valued at US$ Mn.Furthermore, the respective annual growth rates for each of the segments have been provided for the period 2017–2025 by retaining 2016 as the base year.

The report also comprises various qualitative factors that would give an insight into the cell culture monitoring biosensors market and would assist the emerging players in making strategic decisions to enter the market. The factors included are market drivers, opportunities, and restraints. A competitive landscape depicting the market leaders, emerging market players, and promising players has also been incorporated in this report. A complete profile of the key players in this market has also been provided with information on financial performance, marketed products, and company activities. The industrial leaders profiled are Lifeonics, Lonza, Nova Biomedical, Sarissa Biomedical Ltd., Nanomedical Diagnostics, Sierra Sensors GmbH, Conductive Technologies Inc., C-CIT Sensors AG, and VacciXcell.

Based on electrode types, the global cell culture monitoring biosensors market is segmented as follows:

  • Electrochemical
  • Thermometric
  • Optical
  • Piezoelectric

Electrodes form the main component of biosensors that help in the detection of any changes in the cell cultures. The sensors enable the detection of microscopic changes, hydrogen peroxide presence, glucose, glutamate, lactate, a change in temperature, and cell density. The cell culture monitoring biosensors market has been categorized based on the various types of electrodes utilized in the biosensors available in the market, viz., electrochemical, thermometric, optical, and piezoelectric. Of the aforementioned types of electrodes, electrochemical electrodes dominate the market as they are the most widely utilized sensors and have lower pricing, which in turn catapults demand the same. These sensors are capable of both in-situ and online measurements. However, these devices face certain drawbacks, such as the thermal stability of the immobilized enzyme during the sterilization process and electrode degradation due to continuous contact with the sample solution, which may increase the risk of contamination and interfere with the bioprocess. Optical sensors are gaining demand in the current market and are expected to have steady growth in the forecast period, 2017–2025. Optical sensors need minimal invasion in the cell sample, thus having less interference with the bioprocess and providing faster optimization of the sample.

Based on the type of analytes, the global cell culture monitoring biosensors market is segmented as follows:

  • ATP
  • Adenosine
  • Hypoxanthine
  • Glutamate
  • Glucose
  • Lactate
  • Others (Ionosine, Acetylcholine, Choline, & D-Serine)

Cell culture required continuous monitoring to ensure predetermined cell densities and desired metabolic reactions take place accurately. Manual monitoring of the changes in cell culture media, temperature changes, and cell density is time-consuming and increases the risk of contamination as periodic samples need to be taken for testing. To ease this process, various biosensors are available pertaining to the detection and measurement of specific analytes. The cell culture monitoring biosensors market is thus segmented based on the various analytes it could detect and measure, viz., ATP, adenosine, hypoxanthine, glutamate, glucose, lactate, and others. Of the mentioned analytes, glucose is predominantly monitored on a larger scale in every cell culture, followed by glutamate and lactate levels. Glucose is essential in any cell culture as it is the only source of carbon and is essential for cell growth. The glucose consumption levels could also determine the approximate cell density levels. Glucose testing biosensors thus encapsulate the cell culture monitoring biosensors market in the current and forecast periods, 2017–2025. An accurate concentration of glutamate is essential as it is required for the growth of cell culture, but it requires constant monitoring as it is unstable in physiological pH and may lead to the production of ammonium, which is toxic to the cell culture.

Based on the type of end-user, the global cell culture monitoring biosensors market is segmented as follows:

  • Pharmaceutical Industry
  • Research labs
  • Food & Beverages

The pharmaceutical industry, among the rest, holds a dominant position in the cell culture monitoring biosensors market. There is a current rise in the development of biosimilars, biologics, and personalized medicine for the treatment of chronic conditions and orphan indications. For example, the development of the drug kalydeco, which is approved for the treatment of cystic fibrosis in patients with a specific gene mutation, The newer therapies in cancer treatment are based on the personalized medicine concept, which requires a patient’s stem cells to develop the molecule for treatment. The fundamental need for the development of such drugs is cell culture, which requires close monitoring. Thus, with the rise of target-based therapies, the demand for cell culture monitoring biosensors also increases to attain accurate and efficient cell samples. Stem cell research is also on the rise, with various studies being carried out based on stem cell therapy. Thus, research labs also acquire a decent share of the cell culture monitoring biosensors market.

For the purpose of this study, the global cell culture monitoring biosensors market is categorized into three segments:

  • North America
  • Europe
  • Asia Pacific
  • Latin America (LATAM)
  • Middle East and Africa (MEA)

Cell culture studies are carried out across geographies in industries and research institutes. It is an essential part of the drug development process for biologics, biosimilars, and personalized medicines. Thus, cell culture monitoring biosensors have a global existence. Among the geographies researched, North America comprises extensive R&D activities in biologics, biosimilars, and personalized medicines, which propel the growth of cell culture monitoring biosensors. The constant development of healthcare infrastructure in terms of laboratory facilities increased healthcare expenditure, and the presence of key players in North America has also functioned as market catalysts, creating demand for cell culture monitoring biosensors in this region. Europe also holds a key position in the cell culture monitoring biosensors market owing to the presence of key market players in this region, namely Sarissa Biomedical Ltd. and C-CIT Sensors AG, that provide easy access to cell culture monitoring biosensors. Asia Pacific observes a steady increase in the development of biosimilars. As per the Biosimilars APAC Summit, Asia Pacific alone develops a higher number of biosimilar products than any other nation globally. Regulatory bodies are taking initiatives and promoting the growth of more biosimilar products in Asia and the Pacific. The aforementioned development has had a positive impact on the growth of cell culture monitoring biosensors. However, cell culture monitoring biosensors are expensive, which could have a negative impact on their growth in developing economies.

Frequently Asked Qustions:

The market for Cell Culture Monitoring Biosensors is expected to reach US$ 606.3 Mn in 2025.

The Cell Culture Monitoring Biosensors market is expected to see significant CAGR growth over the coming years,at 9.6 %.

The report is forecasted from 2017-2025.

The base year of this report is 2016.

C-CIT Sensors AG.,Conductive Technologies Inc.,Lifeonics,Lonza,Nanomedical Diagnostics are some of the major players in the global market.

 

 

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Trusted By
Godaddy
Published Date:  Nov 2017
Category:  Biotechnology
Report ID:   58859
Report Format:   PDF
Pages:   120
Rating:    4.8 (80)
Delivery Time: 24 Hours to 48 Hours   
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