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N-Butylene Oxide 1,2-Market By Application-Based (Chemical Intermediates, Solvents); By End-User Industry (Chemicals, Pharmaceuticals); By Physical Form (Liquid, Gas); By Purity Level (Industrial Grade, Laboratory Grade); By Distribution Channel (Direct Sales, Online Retail) – Growth, Share, Opportunities & Competitive Analysis, 2024 – 2032

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Published: | Report ID: 111354 | Report Format : Excel, PDF
REPORT ATTRIBUTE DETAILS
Historical Period 2020-2023
Base Year 2024
Forecast Period 2025-2032
N-Butylene Oxide 1,2-Market Size 2024 USD 1,202 million
N-Butylene Oxide 1,2-Market, CAGR 8.6%
N-Butylene Oxide 1,2-Market Size 2032 USD 2,325.4 million

Market Overview:

The N-Butylene Oxide 1,2 market size was valued at USD 1,202 million in 2024 and is anticipated to reach USD 2,325.4 million by 2032, at a CAGR of 8.6% during the forecast period.

The N-Butylene Oxide 1,2 market is led by prominent players such as BASF SE, DuPont, Ningbo Inno Pharmchem, Santa Cruz Biotechnology, Haihang Industry, Hangzhou Dayangchem Co., Ltd, and Kinbester. These companies hold a competitive edge through advanced production technologies, diverse product offerings, and strong global distribution networks. Their strategic focus on expanding application areas and meeting regulatory standards strengthens market positioning. Asia Pacific emerges as the leading regional market, accounting for 34% of the global share in 2024, driven by high demand from the chemical and pharmaceutical industries in China and India, along with cost-efficient manufacturing capabilities.

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Market Insights

  • The N-Butylene Oxide 1,2 market was valued at USD 1,202 million in 2024 and is projected to reach USD 2,325.4 million by 2032, growing at a CAGR of 8.6% during the forecast period.
  • Market growth is primarily driven by increasing demand for chemical intermediates and pharmaceutical solvents, supported by expanding applications in surfactants, polymers, and drug synthesis.
  • Key trends include rising adoption of eco-friendly solvents and technological advancements in production processes to enhance yield and sustainability.
  • Leading players such as BASF SE, DuPont, and Haihang Industry dominate through innovation, but market growth is restrained by stringent environmental regulations and raw material price volatility.
  • Asia Pacific holds the largest regional share at 34%, followed by North America (28%) and Europe (24%), while the Chemical Intermediates segment leads application-based segments due to high demand in industrial formulations.

Market Segmentation Analysis:

By Application-Based

In the N-Butylene Oxide 1,2 market, the Chemical Intermediates segment dominates, accounting for the largest market share in 2024. This dominance is attributed to the compound’s extensive use in synthesizing surfactants, plasticizers, and various specialty chemicals. Growing demand from downstream chemical applications and increasing production of polyurethane and other polymers are key drivers propelling this segment. The Solvents sub-segment also shows promising growth, driven by N-Butylene Oxide’s favorable properties like high solvency and low volatility, which make it suitable for coatings, adhesives, and cleaning agents.

  • For instance, BASF’s Ludwigshafen site produces approximately 8,500,000 metric tons of various chemicals annually across 200 interconnected plants, underscoring its capacity to supply intermediates at scale.

By End-User Industry:

The Chemicals segment holds the dominant position in the N-Butylene Oxide 1,2 market, capturing a significant share due to its critical role in various industrial synthesis processes. The chemical industry’s demand for versatile intermediates fuels continuous consumption of N-Butylene Oxide in the production of esters and glycols. Additionally, the pharmaceuticals segment is witnessing steady growth, driven by the compound’s application in producing drug precursors and specialty pharmaceutical solvents. However, regulatory and safety considerations slightly limit the pharmaceutical segment’s adoption pace compared to the broader chemical industry.

  • For instance, Dow Chemical, BASF and Sinopec hold around 90 percent of global nameplate capacity for N‑Butylene Oxide, enabling large‑scale chemical applications

By Physical Form:

Among the physical forms, Liquid N-Butylene Oxide leads the market with the highest share, driven by its easier handling, storage, and suitability for bulk chemical processing. Liquid form is preferred in large-scale industrial operations for its stability and cost-effectiveness in transport and blending. On the other hand, the Gas form, while niche, is gaining traction in applications requiring precise dosage and controlled reactions, especially in research and high-purity environments. However, limited infrastructure for safe gas handling has restricted its widespread adoption compared to the liquid form.

Market Oervie

Expanding Demand for Chemical Intermediates

The increasing use of N-Butylene Oxide 1,2 as a chemical intermediate in the production of surfactants, plasticizers, and specialty polymers is a major driver of market growth. Industries such as automotive, construction, and consumer goods are witnessing growing demand for these downstream products, thereby fueling the need for efficient intermediates. The versatility of N-Butylene Oxide in chemical synthesis, coupled with its favorable reactivity profile, positions it as a preferred choice for manufacturers seeking cost-effective and scalable production solutions.

  • For instance, BASF’s Ludwigshafen Verbund produces oxo‑C4 surface‑active intermediates with an annual capacity of approximately 1,625,000 metric tons, reflecting its ability to supply large-scale chemical synthesis requirements.

Rising Adoption in Pharmaceutical Manufacturing

N-Butylene Oxide 1,2 is gaining traction in the pharmaceutical industry due to its application in producing drug precursors, solvents, and active pharmaceutical ingredient (API) synthesis. The global expansion of the pharmaceutical sector, driven by increased healthcare expenditure and innovation in drug development, directly supports the demand for high-quality intermediates like N-Butylene Oxide. Its compatibility with regulated environments and utility in formulation processes make it a valuable asset for pharmaceutical manufacturers seeking to enhance efficiency and product purity.

  • For instance, Sinopec’s Yanshan Petrochemical commissioned a CHP‑method plant with an annual output of 4,000 metric tons of N‑Butylene Oxide—demonstrating capability to supply pharmaceutical‑grade intermediates

Technological Advancements in Production Processes

Advancements in catalytic and continuous flow production technologies have enhanced the efficiency and environmental sustainability of N-Butylene Oxide manufacturing. These innovations reduce by-product generation and improve yield, making the compound more commercially viable for large-scale operations. Additionally, investment in process optimization allows for better control over purity levels and customization for specific industrial applications. As industries prioritize greener processes and tighter production tolerances, such technological improvements are accelerating market expansion across regions.

Key Trends & Opportunities

Shift Toward Sustainable and Eco-Friendly Solvents

As industries move toward sustainability, there is a growing opportunity for N-Butylene Oxide 1,2 to be used as a low-toxicity, eco-friendly solvent. Its biodegradability and low environmental persistence make it a suitable alternative in formulations that traditionally rely on more hazardous chemicals. This trend is particularly evident in coatings, adhesives, and cleaning applications. Regulatory pressures for safer chemicals and increasing corporate responsibility initiatives are driving the substitution of conventional solvents with N-Butylene Oxide in green chemistry initiatives.

  • For instance, BASF’s Ludwigshafen site handles high‑volume production of eco‑efficient compounds yielding 8.5 million metric tons per year and promotes low‑VOC innovations.

Emerging Markets Driving Regional Expansion

Rapid industrialization and expanding chemical production capabilities in emerging markets such as India, China, and Southeast Asia present significant growth opportunities. These regions are investing heavily in chemical and pharmaceutical manufacturing infrastructure, creating substantial demand for intermediates like N-Butylene Oxide. Additionally, favorable government policies, improving logistics, and access to raw materials in these regions support market penetration. As companies seek cost advantages and market expansion, these geographies are expected to contribute strongly to global revenue.

  • For instance, BASF’s Nanjing Verbund complex spanning 38 plants and nearly 3 million metric tons capacity exemplifies industrial expansion and positioning in cost‑efficient Asia Pacific.

Key Challenges

Stringent Regulatory Compliance

The production and handling of N-Butylene Oxide 1,2 are subject to stringent environmental and safety regulations due to its potential toxicity and flammability. Complying with guidelines from agencies such as the EPA and REACH adds operational complexity and cost to manufacturers. This regulatory burden may deter smaller companies from entering the market and can lead to delays in product approvals or facility upgrades, thereby restricting growth potential in highly regulated markets.

Fluctuating Raw Material Prices

The market is vulnerable to volatility in the prices of key raw materials such as butanol and ethylene oxide, which are influenced by global petrochemical trends. Sudden price hikes or supply chain disruptions can significantly impact production costs, affecting profit margins and pricing strategies. This cost unpredictability poses a challenge, especially for manufacturers with limited vertical integration or those operating in price-sensitive end-user markets.

Limited Awareness in Niche Applications

Despite its versatile properties, N-Butylene Oxide 1,2 remains underutilized in certain niche applications due to limited awareness among small and mid-sized manufacturers. The lack of technical understanding and application-specific knowledge often results in reliance on conventional chemicals. Expanding educational outreach and demonstrating cost-benefit advantages will be crucial to unlocking the compound’s full market potential in sectors such as electronics, agrochemicals, and specialty formulations.

Regional Analysis

North America

North America holds a substantial share in the global N-Butylene Oxide 1,2 market, accounting for approximately 28% of the total market in 2024. The region’s dominance is supported by strong demand from the chemical and pharmaceutical industries, coupled with well-established manufacturing infrastructure and robust regulatory compliance. The United States leads the region due to significant investments in chemical intermediates and solvent applications. Ongoing research and development activities, along with a focus on sustainable chemical production, further support growth. However, high operational costs and stringent environmental regulations may temper expansion over the forecast period.

Europe

Europe captures nearly 24% of the global N-Butylene Oxide 1,2 market, driven by rising adoption in pharmaceutical formulations and specialty chemicals. Countries like Germany, France, and the UK lead due to their advanced industrial ecosystems and strict environmental standards promoting cleaner intermediates. The region’s strong regulatory framework and sustainability focus contribute to increasing demand for eco-friendly solvents and intermediates like N-Butylene Oxide. Innovation in green chemistry and cross-border collaborations with research institutions further enhance growth prospects. Nonetheless, economic fluctuations and compliance costs continue to challenge regional producers, particularly small and mid-sized enterprises.

Asia Pacific

Asia Pacific dominates the global N-Butylene Oxide 1,2 market with an estimated 34% share in 2024, led by rapid industrialization and expanding pharmaceutical and chemical sectors in China, India, Japan, and South Korea. The region benefits from cost-effective raw materials, favorable government policies, and a growing export-oriented manufacturing base. China alone contributes a significant portion due to its large-scale chemical output and rising investment in intermediates. Increasing demand for personal care products, agrochemicals, and surfactants also fuels growth. However, regulatory inconsistencies and environmental concerns in some areas may pose challenges to sustainable market expansion.

Latin America

Latin America holds a modest 7% share of the global N-Butylene Oxide 1,2 market, supported primarily by developments in Brazil, Mexico, and Argentina. The region is witnessing steady growth due to rising investment in chemical and pharmaceutical sectors, along with increasing demand for solvents and intermediates. Local production remains limited, making the region dependent on imports, but expanding manufacturing capacities and regional trade agreements are enhancing supply chain efficiency. Infrastructure gaps and regulatory variations across countries, however, can hinder uniform market development and restrict full-scale growth potential.

Middle East & Africa

The Middle East & Africa region accounts for approximately 7% of the global market, with growth fueled by increasing investments in downstream petrochemical industries and the rising demand for industrial solvents. Countries such as Saudi Arabia, the UAE, and South Africa are emerging as key players in regional consumption. Government initiatives to diversify economies and establish chemical processing hubs contribute to market advancement. However, the region still faces challenges such as limited technical expertise, regulatory constraints, and fluctuating raw material availability, which may slow down market penetration and impact long-term sustainability.

Market Segmentations:

By Application-Based:

  • Chemical Intermediates
  • Solvents

By End-User Industry:

  • Chemicals
  • Pharmaceuticals

By Physical Form:

  • Liquid
  • Gas

By Purity Level:

  • Industrial Grade
  • Laboratory Grade

By Distribution Channel:

  • Direct Sales
  • Online Retail

By Geography

  • North America
    • U.S.
    • Canada
    • Mexico
  • Europe
    • Germany
    • France
    • U.K.
    • Italy
    • Spain
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • South-east Asia
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Argentina
    • Rest of Latin America
  • Middle East & Africa
    • GCC Countries
    • South Africa
    • Rest of the Middle East and Africa

Competitive Landscape

The competitive landscape of the N-Butylene Oxide 1,2 market is characterized by the presence of both global and regional players actively engaged in product innovation, capacity expansion, and strategic partnerships. Key industry participants such as BASF SE, DuPont, Ningbo Inno Pharmchem, Santa Cruz Biotechnology, and Haihang Industry hold a significant share of the market owing to their strong manufacturing capabilities and diverse product portfolios. These companies focus on enhancing production efficiency and complying with evolving environmental regulations to maintain a competitive edge. Additionally, several firms are investing in research and development to improve purity levels and expand application scope, particularly in the pharmaceutical and specialty chemicals sectors. Mergers, acquisitions, and collaborations are common strategies adopted to strengthen global distribution networks and tap into emerging markets. Competitive dynamics are also influenced by the ability to manage raw material volatility and meet customized requirements, positioning innovation and supply chain resilience as key differentiators in the market.

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Key Player Analysis

  • DuPont
  • Ningbo Inno Pharmchem
  • Santa Cruz Biotechnology
  • Haihang Industry
  • Kinbester
  • BASF SE
  • Hangzhou Dayangchem Co Ltd

Recent Developments

  • In June 2025, DuPont is reported to be strategically shifting its investments towards high-value specialty materials, although this focus doesn’t specifically include N-Butylene Oxide 1-2. The broader chemical industry is also experiencing a push towards more sustainable and circular economies, with a focus on bio-based chemicals and biorefineries.
  • In May 2025, DuPont was recognized as a major global producer of N-Butylene Oxide 1-2. While no specific process innovations were announced for this chemical, DuPont remains a key supplier responding to the increasing demand for specialty chemicals used in intermediates, stabilizers, and surfactants. Market reports from 2025 highlight DuPont’s influence on the N-Butylene Oxide 1-2 market and its competitive landscape.
  • In March 2025, BASF’s Asia Pacific division implemented price increases for polyurethane formulations, directly driven by rising raw material costs. This action was part of broader efforts to enhance profitability and competitiveness and to engage in US anti-dumping actions related to MDI derivatives. These broader initiatives, however, are not directly related to N-Butylene Oxide 1-2.

Market Concentration & Characteristics

The N-Butylene Oxide 1,2 market exhibits a moderately concentrated structure, with a few dominant players controlling a significant share of global production and supply. Leading manufacturers such as BASF SE, DuPont, and Haihang Industry operate with strong distribution networks, advanced production capabilities, and established relationships across end-user sectors. It maintains high entry barriers due to stringent regulatory compliance, complex manufacturing processes, and capital-intensive infrastructure. The market reflects characteristics of specialized chemical demand, where consistency in purity levels and supply reliability are critical. Buyers typically include large-scale chemical and pharmaceutical companies that prioritize long-term supplier relationships and quality certifications. It is characterized by continuous product optimization and innovation, particularly in eco-friendly formulations and purity enhancements. Regional competitiveness depends on raw material access, labor costs, and technological advancement, with Asia Pacific emerging as the dominant production hub. The market responds strongly to shifts in regulatory policies, environmental standards, and application-specific performance expectations.

Report Coverage

The research report offers an in-depth analysis based on Application-Based, End-User Industry, Physical Form, Purity Level, Distribution Channel and Geography. It details leading market players, providing an overview of their business, product offerings, investments, revenue streams, and key applications. Additionally, the report includes insights into the competitive environment, SWOT analysis, current market trends, as well as the primary drivers and constraints. Furthermore, it discusses various factors that have driven market expansion in recent years. The report also explores market dynamics, regulatory scenarios, and technological advancements that are shaping the industry. It assesses the impact of external factors and global economic changes on market growth. Lastly, it provides strategic recommendations for new entrants and established companies to navigate the complexities of the market.

Future Outlook

  1. The market will continue to grow steadily driven by rising demand for chemical intermediates in industrial manufacturing.
  2. Pharmaceutical applications will expand due to increased use of N-Butylene Oxide 1,2 in drug synthesis and solvent systems.
  3. Asia Pacific will remain the leading region, supported by low-cost production and growing domestic demand.
  4. Manufacturers will invest in production efficiency and process optimization to meet rising purity and quality standards.
  5. Regulatory compliance will become more critical, pushing companies to adopt environmentally safe manufacturing practices.
  6. The shift toward green and bio-based solvents will open new application opportunities for N-Butylene Oxide 1,2.
  7. Strategic partnerships and acquisitions will shape competitive dynamics and enhance global market reach.
  8. Technological advancements will enable the development of tailored formulations for specific end-user requirements.
  9. Supply chain resilience will gain focus to manage raw material volatility and ensure consistent output.
  10. Emerging economies will play a key role in market expansion through infrastructure growth and industrial development.

1. Introduction  

1.1. Report Description

1.2. Purpose of the Report

1.3. USP & Key Offerings

1.4. Key Benefits for Stakeholders

1.5. Target Audience

1.6. Report Scope

1.7. Regional Scope

 

2. Scope and Methodology  

2.1. Objectives of the Study

2.2. Stakeholders

2.3. Data Sources

2.3.1. Primary Sources

2.3.2. Secondary Sources

2.4. Market Estimation

2.4.1. Bottom-Up Approach

2.4.2. Top-Down Approach

2.5. Forecasting Methodology

 

3. Executive Summary  

 

4. Introduction  

4.1. Overview

4.2. Key Industry Trends

 

5. Global N-Butylene Oxide 1-2-Market  

5.1. Market Overview

5.2. Market Performance

5.3. Impact of COVID-19

5.4. Market Forecast

 

6. Market Breakup By Application-Based  

6.1. Chemical Intermediates

6.1.1. Market Trends

6.1.2. Market Forecast

6.1.3. Revenue Share

6.1.4. Revenue Growth Opportunity

6.2. Solvents

6.2.1. Market Trends

6.2.2. Market Forecast

6.2.3. Revenue Share

6.2.4. Revenue Growth Opportunity

 

7. Market Breakup By End-User Industry  

7.1. Chemicals

7.1.1. Market Trends

7.1.2. Market Forecast

7.1.3. Revenue Share

7.1.4. Revenue Growth Opportunity

7.2. Pharmaceuticals

7.2.1. Market Trends

7.2.2. Market Forecast

7.2.3. Revenue Share

7.2.4. Revenue Growth Opportunity

 

8. Market Breakup By Physical Form  

8.1. Liquid

8.1.1. Market Trends

8.1.2. Market Forecast

8.1.3. Revenue Share

8.1.4. Revenue Growth Opportunity

8.2. Gas

8.2.1. Market Trends

8.2.2. Market Forecast

8.2.3. Revenue Share

8.2.4. Revenue Growth Opportunity

 

9. Market Breakup By Purity Level  

9.1. Industrial Grade

9.1.1. Market Trends

9.1.2. Market Forecast

9.1.3. Revenue Share

9.1.4. Revenue Growth Opportunity

9.2. Laboratory Grade

9.2.1. Market Trends

9.2.2. Market Forecast

9.2.3. Revenue Share

9.2.4. Revenue Growth Opportunity

 

10. Market Breakup By Distribution Channel  

10.1. Direct Sales

10.1.1. Market Trends

10.1.2. Market Forecast

10.1.3. Revenue Share

10.1.4. Revenue Growth Opportunity

10.2. Online Retail

10.2.1. Market Trends

10.2.2. Market Forecast

10.2.3. Revenue Share

10.2.4. Revenue Growth Opportunity

 

11. Market Breakup by Region  

11.1. North America

11.1.1. United States

11.1.1.1. Market Trends

11.1.1.2. Market Forecast

11.1.2. Canada

11.1.2.1. Market Trends

11.1.2.2. Market Forecast

11.2. Asia-Pacific

11.2.1. China

11.2.2. Japan

11.2.3. India

11.2.4. South Korea

11.2.5. Australia

11.2.6. Indonesia

11.2.7. Others

11.3. Europe

11.3.1. Germany

11.3.2. France

11.3.3. United Kingdom

11.3.4. Italy

11.3.5. Spain

11.3.6. Russia

11.3.7. Others

11.4. Latin America

11.4.1. Brazil

11.4.2. Mexico

11.4.3. Others

11.5. Middle East and Africa

11.5.1. Market Trends

11.5.2. Market Breakup by Country

11.5.3. Market Forecast

 

12. SWOT Analysis  

12.1. Overview

12.2. Strengths

12.3. Weaknesses

12.4. Opportunities

12.5. Threats

 

13. Value Chain Analysis  

 

14. Porters Five Forces Analysis  

14.1. Overview

14.2. Bargaining Power of Buyers

14.3. Bargaining Power of Suppliers

14.4. Degree of Competition

14.5. Threat of New Entrants

14.6. Threat of Substitutes

 

15. Price Analysis  

 

16. Competitive Landscape  

16.1. Market Structure

16.2. Key Players

16.3. Profiles of Key Players

16.3.1. DuPont

16.3.1.1. Company Overview

16.3.1.2. Product Portfolio

16.3.1.3. Financials

16.3.1.4. SWOT Analysis

16.3.2. Ningbo Inno Pharmchem

16.3.2.1. Company Overview

16.3.2.2. Product Portfolio

16.3.2.3. Financials

16.3.2.4. SWOT Analysis

16.3.3. Santa Cruz Biotechnology

16.3.3.1. Company Overview

16.3.3.2. Product Portfolio

16.3.3.3. Financials

16.3.3.4. SWOT Analysis

16.3.4. Haihang Industry

16.3.4.1. Company Overview

16.3.4.2. Product Portfolio

16.3.4.3. Financials

16.3.4.4. SWOT Analysis

16.3.5. Kinbester

16.3.5.1. Company Overview

16.3.5.2. Product Portfolio

16.3.5.3. Financials

16.3.5.4. SWOT Analysis

16.3.6. BASF SE

16.3.6.1. Company Overview

16.3.6.2. Product Portfolio

16.3.6.3. Financials

16.3.6.4. SWOT Analysis

16.3.7. Hangzhou Dayangchem Co Ltd

16.3.7.1. Company Overview

16.3.7.2. Product Portfolio

16.3.7.3. Financials

16.3.7.4. SWOT Analysis

 

17. Research Methodology  

 

Frequently Asked Questions

What is the current size of the N-Butylene Oxide 1-2 Market?

The market size was valued at USD 1,202 million in 2024.

What factors are driving the growth of the N-Butylene Oxide 1-2 Market?

Rising demand for chemical intermediates and pharmaceutical solvents is driving market expansion.

What are some challenges faced by the N-Butylene Oxide 1-2 Market?

Key challenges include stringent regulations, raw material price fluctuations, and limited awareness in niche sectors.

Who are the major players in the N-Butylene Oxide 1-2 Market?

Major players include BASF SE, DuPont, Haihang Industry, Santa Cruz Biotechnology, and Ningbo Inno Pharmchem.

About Author

Shweta Bisht

Shweta Bisht

Healthcare & Biotech Analyst

Shweta is a healthcare and biotech researcher with strong analytical skills in chemical and agri domains.

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Gunakesh Parmar

Reviewed By
Gunakesh Parmar

Research Consultant

With over 15 years of dedicated experience in market research since 2009, specializes in delivering actionable insights from data.

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