Home / Pharmaceuticals / Alpha Mannosidosis Market By Indication Type (Type I, Type II, Type III), By Treatment (Bone Marrow Treatment, Enzyme Replacement Treatment) - Growth, Future Prospects, And Competitive Analysis, 2017 -2025

Alpha Mannosidosis Market By Indication Type (Type I, Type II, Type III), By Treatment (Bone Marrow Treatment, Enzyme Replacement Treatment) - Growth, Future Prospects, And Competitive Analysis, 2017 -2025

Published: Oct 2018 | Report Code: 58561-10-18

Aplha mannosidosis is a rare genetic disorder belonging to a group of diseases known as lysosomal storage disorders. Aplha mannosidosis occurs in 1 in every 500,000 people in the general population and is characterized by a deficiency of the enzyme alpha-D-mannosidase. The symptoms, progression and severity of alpha-mannosidosis vary widely from one person to another, including between siblings who share the same mutation.

The report titled “Global Alpha Mannosidosis Market- Growth, Future Prospects and Competitive Analysis, 2017–2025” offers strategic insights into the alpha mannosidosis market along with the market size and estimates for the duration 2017 to 2025. The research study covers in-depth analysis of market segments based on Indication type, treatment and different geographical region.

In order to help strategic decision makers, the report also includes competitive profiling of the leading players in global alpha mannosidosis market, attractive investment proposition and market positioning of key manufacturers sections.

Geographically, the global alpha mannosidosis market is studied for the following regional markets:

  • North America
    • U.S.
    • Canada
  • Europe
    • U.K.
    • Germany
    • Rest of Europe
  • Asia-Pacific
    • China
    • Japan
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East and Africa
    • GCC
    • Rest of MEA

Market size and forecast for these regional and country level markets are presented in this study for the period 2015-2025. Market growth rates for the forecast period 2017-2025 are also included in this report, considering 2016 as the base year.

Along with quantitative information, qualitative information sets and assessment tools are provided in this study for better analysis of the overall market scenario and future prospects. Information such as market inclination insights and drivers, challenges and opportunities assists the readers for understanding the ongoing trends in the global alpha mannosidosis market. Tools such as market positioning of key players and attractive investment proposition provide the readers with insights on the competitive scenario of the global alpha mannosidosis market. This report concludes with company profiles section that highlights major information about the key players engaged in global alpha mannosidosis market. In-depth competitive environment analysis and historical years (2015) market size data are also provided in the report. 

Thus, the research study provides a holistic view of the global alpha mannosidosis market, offering market size and estimates for the period from 2017 to 2025, keeping in mind the above-mentioned factors.

Alpha Mannosidosis Market

Chapter 1 Preface
1.1 Report Description
1.1.1 Purpose of the Report
1.1.2 Target Audience
1.1.3 USP and Key Offerings
1.2 Research Scope
1.3 Research Methodology
1.3.1 Phase I – Secondary Research
1.3.2 Phase II – Primary Research
1.3.3 Phase III – Expert Panel Review
1.3.4 Assumptions

Chapter 2 Executive Summary
2.1 Alpha Mannosidosis Market Portraiture
2.2 Alpha Mannosidosis Market, by Indication Type, 2016 (US$ Mn)
2.3 Alpha Mannosidosis Market, by Treatment, 2016 (US$ Mn)
2.4 Alpha Mannosidosis Market, by Geography, 2016 (Value %)

Chapter 3 Global Alpha Mannosidosis Market Analysis
3.1 Global Alpha Mannosidosis Market Overview
3.2 Market Dynamics
3.2.1 Market Drivers
3.2.2 Challenges
3.2.3 Opportunities
3.3 Epidemiology of Alpha Mannosidosis
3.4 Attractive Investment Proposition, by Geography, 2017 
3.5 Competitive Analysis: Global Alpha Mannosidosis Market, 2016 (Value %)

Chapter 4 Global Alpha Mannosidosis Market Analysis, By Indication Type
4.1 Overview
4.1.1 Market Attractive Proposition of Alpha Mannosidosis Market, by
Indication, 2016
4.2 Type I
4.3 Type II
4.4 Type III

Chapter 5 Global Alpha Mannosidosis Market Analysis, By Treatment
5.1 Overview
5.1.1 Market Attractive Proposition of Alpha Mannosidosis Market, by
Treatment, 2016
5.2 Bone Marrow Treatment
5.3 Enzyme Replacement Treatment

Chapter 6 Global Alpha Mannosidosis Market, By Geography
6.1 Preface
6.2 North America (U.S. & Canada)
6.3 Europe (U.K., Germany & Rest of Europe)
6.4 Asia-Pacific (China, Japan & Rest of Asia-Pacific)
6.5 Latin America (Brazil, Mexico and Rest of LATAM)
6.6 Middle East and Africa (GCC and Rest of MEA)

Chapter 7 Company Profiles
7.1 Zymenex (Chiesi Farmaceutici S.p.A)

List Of Table: 

TABLE 1 Global Alpha Mannosidosis Market, By Indication Type (US$ Mn), 2015– 2025 (Value)
TABLE 2 Global Alpha Mannosidosis Market, By Treatment (US$ Mn), 2015– 2025 (Value)
TABLE 3 Global Alpha Mannosidosis Market, by Geography, 2015 – 2025 (US$ Mn)
TABLE 4 North America Alpha Mannosidosis Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 5 Europe Alpha Mannosidosis Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 6 Asia - Pacific Alpha Mannosidosis Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 7 Latin America Alpha Mannosidosis Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 8 Middle East and Africa Alpha Mannosidosis Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 9 Zymenex (Chiesi Farmaceutici S.p.A): Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)

List Of Figures :

FIG. 1 Alpha Mannosidosis Market: Research Methodology
FIG. 2 Alpha Mannosidosis Market, by Indication Type, 2016 (US$ Mn)
FIG. 3 Alpha Mannosidosis Market, by Treatment, 2016 (US$ Mn)
FIG. 4 Alpha Mannosidosis Market, by Geography, 2016 (Value %)
FIG. 5 Attractive Investment Proposition
FIG. 6 Competitive Analysis: Global Alpha Mannosidosis Market, 2016 (Value %)
FIG. 7 Global Type I Alpha Mannosidosis Market(US$ Mn), 2015-2025
FIG. 8 Global Type II Alpha Mannosidosis Market(US$ Mn), 2015-2025
FIG. 9 Global Type III Alpha Mannosidosis Market (US$ Mn), 2015-2025
FIG. 10 Global Bone Marrow Treatment Market (US$ Mn), 2015-2025
FIG. 11 Global Enzyme Replacement Treatment Market (US$ Mn), 2015-2025

Based on the type of Indication the global alpha mannosidosis market is segmented as follows:

  • Type I
  • Type II
  • Type III

Aplha mannosidosis is a rare genetic disorder belonging to a group of diseases known as lysosomal storage disorders. Aplha mannosidosis occurs in 1 in every 500,000 people in the general population and is characterized by a deficiency of the enzyme alpha-D-mannosidase. The symptoms, progression and severity of alpha-mannosidosis vary widely from one person to another, including between siblings who share the same mutation. The commonly seen signs of dysfunctions in the people with alpha mannosidosis include intellectual disability, skeletal abnormalities and distinctive facial features. The global alpha mannosidosis market is segmented into three separate subtypes such as mild (type I), moderate (type II) and severe (type III). The type II indication held the largest share in the global alpha mannosidosis market due to high prevalence of type II alpha mannosidosis. The Type II indication is expected to grow during the forecast period due to rising prevalence of alpha mannosidase. Moreover, ongoing clinical trials for the treatment of alpha mannosidosis would further drive the market during the forecast period.

Alpha Mannosidosis Market

Based on the type of treatment, the alpha mannosidosis market is segmented into:

  • Bone Marrow Transplant (BMT)
  • Enzyme Replacement Therapy (ERT)

Alpha Mannosidosis belongs to a group of diseases known as the lysosomal storage disorders. The prevalence of alpha-mannosidosis is estimated to be 1 in every 500,000 people in the general population. Alpha-mannosidosis affects men and women in equal numbers and can potentially affect individuals of any ethnic group worldwide. The treatment option for alpha mannosidosis is symptomatic and supportive. The alpha mannosidosis market on the basis of treatment has been segmented into bone marrow treatment and enzyme replacement therapy. Bone marrow treatment is under clinical trial for the treatment of alpha mannosidosis. However, BMT procedure is expensive and carries the risk of serious complications including graft-versus-host disease and other long-term effects. Enzyme replacement therapy involves replacing a missing enzyme in individuals who are deficient or lack the particular enzyme in question. Lamazym, an enzyme replacement therapy, is under the late stage of clinical trials as a potential treatment for individuals with alpha-mannosidosis. Moreover, Gene therapy is also being studied as another possible approach to therapy for some lysosomal storage disorders.

Alpha Mannosidosis Market

For the purpose of this study, the global alpha mannosidosis market is categorized as follows:

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa

Alpha Mannosidosis Market

For the purpose of this study, the global alpha mannosidosis market is segmented into regional markets such as North America, Europe, Asia Pacific, Latin America, Middle East and Africa. North America held the largest share in the alpha mannosidosis market due increased clinical trials in the regions. After the Orphan Drugs Act passed in the U.S., the development and approval of drugs for orphan diseases has escalated. As a result, it has emerged as the biggest benefit for the pharmaceutical companies to launch orphan drugs in a fast track basis. The ERT drug for alpha mannosidosis named Lamazym has also been given the orphan drug status across Europe and the U.S. Asia Pacific is projected to grow at a fastest growth rate during the forecast period. The growth will be attributed to the rising awareness about the disease in the developing countries. Government of Australia has implemented a national plan for helping patients with rare diseases to reduce the mortality rate due to these diseases. The plan aims to raise awareness about the burden of rare diseases among patients, its impact on social life, and healthcare professionals.

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