ADME is the abbreviation for absorption, distribution, metabolism and elimination, a pharmacology and pharmacokinetics term that describes the disposition of a drug or compound inside the human body. ADME comprises set of four processes that develop the performance of a drug on human tissue and ADME toxicology testing is applied for the development of a new drug. With advancement of technology and reliability of ADME testing, due to its accurate and predictable result, its usage in drug development and initial screening for novel product has increased
The report titled “Global In-Vitro ADME Services Market - Growth, Share, Opportunities and Competitive Analysis, 2016–2023” offers strategic insights into the overall In-Vitro ADME Services market along with the market size and estimates for the duration 2016 to 2023. The said research study covers in-depth analysis of multiple market segments based on type of service and different geographical region. The service type segment studied for analyzing the overall In-Vitro ADME Services market is majorly segmented into Solution Properties, Drug Absorption and Transport, Drug metabolism and Drug-Drug interaction.
In order to help strategic decision makers, the report also includes competitive profiling of the leading players in In-Vitro ADME Services market, attractive investment proposition market positioning of key manufacturers sections. Other in-depth analysis provided in the report includes:
Geographically, the global In-Vitro ADME Services market is studied for the following regional markets:
Market size and forecast for these regional and country level markets are presented in this study for the period 2013-2023. Market growth rates for the forecast period 2016-2023 are also included in this report, considering 2015 as the base year.
Along with quantitative information, qualitative information sets and assessment tools are provided in this study for better analysis of the overall market scenario and future prospects. Information such as market inclination insights and drivers, challenges and opportunities assists the readers for understanding the ongoing trends in the global In-Vitro ADME Services market. Tools such as market positioning of key players and attractive investment proposition provide the readers with insights on the competitive scenario of the global In-Vitro ADME Services market. This report concludes with company profiles section that highlights major information about the key players engaged in global In-Vitro ADME Services market. In-depth competitive environment analysis and historical years (2013 & 2014) market size data are also provided in the report.
Thus, the research study provides a holistic view of the global In-Vitro ADME Services market, offering market size and estimates for the period from 2016 to 2023, keeping in mind the above-mentioned factors.
Chapter 1 Preface
1.1 Report Description
1.1.1 Purpose of the Report
1.1.2 Target Audience
1.1.3 USP and Key Offerings
1.2 Research Scope
1.3 Research Methodology
1.3.1 Phase I – Secondary Research
1.3.2 Phase II – Primary Research
1.3.3 Phase III – Expert Panel Review
1.3.4 Assumptions
Chapter 2 Executive Summary
2.1 Global In-Vitro ADME Services Market Portraiture
2.2 Global In-Vitro ADME Services Market, by Type, 2015 (US$ Mn)
2.3 Global In-Vitro ADME Services Market, by Geography, 2015 (Value %)
Chapter 3 Market Dynamics: In Vitro ADME Services Market
3.1 In Vitro ADME Services Market Analysis
3.2 Future Market Trend: In Vitro ADME Services
3.3 Regulatory Market Scenario
3.4 Mergers and Acquisition
3.5 Market Dynamics
3.5.1 Market Divers
3.5.1.1 Raising ethical concern regarding animal testing
3.5.1.2 Advancement in R&D for early detection of toxicity
3.5.1.3 Lack of comprehensive databases of in-vitro test methods
3.5.2 Challenges
3.5.2.1 Due to predictive paradise, decline in use of in vitro testing
3.5.2.2 In Vitro Models inability to Detect Autoimmunity &Immunostimulation
3.5.3 Opportunities
3.5.3.1 Surge in demand of in vitro ( pre-clinical ADME Tox) method for drug development and screening and various toxicology programs
3.6 Attractive Investment Proposition
3.7 Market Share Analysis: Key In- Vitro ADME Service Providers, 2015 (%)
Chapter 4 Global In-Vitro ADME Services Market Analysis, by Type
4.1 Introduction
4.2 Solution Properties
4.3 Drug Absorption & Transport
4.4 Drug Metabolism
4.5 Drug – Drug Interactions
Chapter 5 Global In-Vitro ADME Services Market, by Geography
5.1 Preface
5.2 North America (U.S. & Canada)
5.3 Europe (U.K., Germany & Rest of Europe)
5.4 Asia Pacific (China, Japan, Singapore, South Korea and Rest of APAC)
5.5 Latin America (Mexico, Brazil and Rest of LATAM)
5.6 Middle East and Africa
Chapter 6 Company Profiles
6.1 Absorption Systems LP
6.2 Albany Molecular Research, Inc. (AMRI)
6.3 Aptagen, LLC
6.4 BIOalternatives SAS
6.6 Sigma-Aldrich Co. LLC/ MilliporeSigma
6.8 BioTeSys GmbH
6.9 Calvert Labs
6.10 XenoTech, LLC
6.11 Cyprotex PLC
6.12 Qualyst Transporter Solution, LLC
6.13 Solvo Biotechnology
6.14 TNO
6.15 WuXiAppTec
6.17 Centrillion Technology Holdings Ltd.
6.18 In Vitro ADMET Laboratories, LLC
6.19 Covance, Inc.
6.20 Quintiles IMS Holdings, Inc.
6.21 Optivia Biotechnology Inc.
6.23 PharmaronBeijing Company Ltd.
6.25 Quest Pharmaceutical Services Holdings LLC
6.26 Thermo Fisher Scientific Inc.
6.28 Charles River Laboratories International, Inc.
6.30 EurofinsCerep SA
6.31 Admescope
6.33 Agilux
6.35 Alliance Pharma
6.36 BD Biosciences
6.37 Frontage Laboratories
6.39 MICROCONSTANTS, INC.
Note:
List of Tables :
TABLE 1 Global In-Vitro ADME Services Market, by Type, 2013-2023 (US$ Mn)
TABLE 2 Global In-Vitro ADME Services Market, by Geography, 2013 – 2023 (US$ Mn)
TABLE 3 North America In-Vitro ADME Services Market, by Type, 2013 – 2023 (US$ Mn)
TABLE 4 North America In-Vitro ADME Services Market, by Geography, 2013 – 2023 (US$ Mn)
TABLE 5 Europe In-Vitro ADME Services Market, by Type, 2013 – 2023 (US$ Mn)
TABLE 6 Europe In-Vitro ADME Services Market, by Geography, 2013 – 2023 (US$ Mn)
TABLE 7 Asia Pacific In-Vitro ADME Services Market, by Type, 2013 – 2023 (US$ Mn)
TABLE 8 Asia-Pacific In-Vitro ADME Services Market, by Geography, 2013 – 2023 (US$ Mn)
TABLE 9 Latin America In-Vitro ADME Services Market, by Type, 2013 – 2023 (US$ Mn)
TABLE 10 Latin America In-Vitro ADME Services Market, by Geography, 2013 – 2023 (US$ Mn)
TABLE 11 Middle-East and Africa In-Vitro ADME Services Market, by Type, 2013 – 2023 (US$ Mn)
TABLE 12 Absorption Systems LP: Company Snapshot (Business Description; Financial Health and Budget Allocation; Product Position/Portfolio; News Coverage)
TABLE 13 Albany Molecular Research, Inc. (AMRI): Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 14 Aptagen, LLC: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 15 BIOalternatives SAS: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 16 Sigma-Aldrich Co, LLC/MilliporeSigma: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 17 BioTeSys GmbH: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 18 Calvert Labs: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 19 XenoTech, LLC: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 20 Cyprotex PLC: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 21 Qualyst Transporter Solutions, LLC: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 22 Solvo Biotechnology: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 23 TNO: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 24 WuXiAppTec: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 25 Centrillion Technology Holdings Ltd.: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 26 In Vitro ADMET Laboratories, LLC: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 27 Covance, Inc.: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 28 Quintiles IMS Holdings, Inc.: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 29 Optivia Biotechnology Inc.: Company Snapshot (Business Description; Financial Health and Budget Allocation; Product Position/Portfolio; News Coverage)
TABLE 30 PharmaronBeijing Company Ltd.: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 31 Quest Pharmaceuticals Services Holdings LLC: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 32 Thermo Fisher Scientific Inc.: Company Snapshot (Business Description; Financial Health and Budget Allocation; Product Position/Portfolio; News Coverage)
TABLE 33 Charles River Laboratories International, Inc.: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 34 EurofinsCerep SA: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 35 Admescope: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 36 Agilux: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 37 Alliance Pharma: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 38 BD Biosciences: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 39 Frontage Laboratories: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
TABLE 40 MICROCONSTANTS, INC.: Company Snapshot (Business Description; Financial Performance; Product Position/Portfolio; News Coverage)
List of Figures :
FIG. 1 In-Vitro ADME Services Market: Research Methodology
FIG. 2 Global In-Vitro ADME Services Market, by Type, 2015 (US$ Mn)
FIG. 3 Global In-Vitro ADME Services Market, by Geography, 2015 (Value %)
FIG. 4 Provisional Timeline of Toxicokinetics
FIG. 5 Attractive Investment Proposition, by Geography, 2015
FIG. 6 Market Share Analysis Key In-Vitro ADME Service Providers, 2015 (%)
FIG. 7 Solution Properties Services Market, 2013 – 2023 (US$ Mn)
FIG. 8 Drug Absorption & Transport Services Market, 2013 – 2023 (US$ Mn)
FIG. 9 Drug Metabolism Services Market, 2013 – 2023 (US$ Mn)
FIG. 10 Drug – Drug Interactions Services Market, 2013 – 2023 (US$ Mn)
FIG. 11 Middle East & Africa In-Vitro ADME Market , 2013 – 2023 (US$ Mn)
Based on the type of product, the Global In-Vitro ADME Services Market is segmented as follows:
In 2015, drug absorption and transport was observed as the largest segment followed by drug metabolism due to factors such as cost-efficiency, rising demand for novel technologies and increasing research and development activities in the field of pharmaceutical and biopharmaceutical industries. Drug absorption and transport mainly involves processes such as parallel artificial membrane permeability assay (PAMPA) permeability screening, Caco-2 permeability screening, MDCK permeability, and transporter assay platform. Drug absorption and transport is followed by drug metabolism mainly due to presence of high market demand, increasing surveillance of regulatory bodies and rising research and development activities in field of medicine. Service providers operating in drug metabolism services help to identify the metabolic pathways, potential interactions and routes of elimination of compound at an early stage. The pharmaceutical industry has been evolving in recent years, along with several CROs and biotech companies conducting drug discovery and development programs and services in Asia-Pacific. It was also observed that broad and vital technology platform bridges efficacy and safety, the drug metabolism and pharmacokinetics has become a mature discovery function to optimize ADME properties in drug design and screening, and dramatically mitigate attrition rates during the last decades.
For the purpose of this study, the Global In-Vitro ADME Services Market is categorized into:
The global In- Vitro ADME market is bifurcated into four regions: North America, Europe, Asia-Pacific, Latin America and Middle East. The global In-Vitro ADME services market is dominated by the Europe region occupying the major market. The growth in Europe is attributed to increasing due to research and development taking place w.r.t drug discovery and drug metabolism at the academic level. Moreover, most of the research activities are carried out in the region and not outsourced to the other regions. Asia-Pacific In-Vitro ADME services market is the fastest growing market in the world. The market is likely to grow with the increase in drug discovery efforts in the pharmaceutical industry. It is expected that the In-Vitro ADME services market in Latin America and Middle East and Africa will witness rapid growth in the given period of forecast.
