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Lambert-Eaton Myasthenic Syndrome Market By Treatment (Potassium Channel Blockers (Amifampridine), Cholinesterase Inhibitor (Pyridostigmine), Immune Therapy, Intravenous Immunoglobulin, Plasmapheresis) – Growth, Future Prospects And Competitive Landscape, 2019 – 2027

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Published: | Report ID: 7941 | Report Format : PDF

Market Insights

The Lambert-Eaton myasthenic syndrome (LEMS) market is keen to represent linear growth at a compounded annual growth rate (CAGR) of 6.7% during the forecast period from 2019 to 2027. LEMS is a rare autoimmune disorder that is manifested by the clinical triad of reduced tendon reflexes, autonomic symptoms, and proximal muscle weakness. Because of the overlapping symptoms with small cell lung cancer (SCLC), the majority of LEMS patients go undiagnosed at a young age.

Market Synopsis

Recent FDA approval of amifampridine for the treatment of LEMS in children, as well as fast track and orphan drug designation, will encourage growth during the forecast period.

Currently, there is no permanent cure for the treatment of LEMS disease in children; the medicine prescribed by physicians worldwide is intended to attenuate the clinical manifestations related to LEMS disease. Depending on the identification of the symptoms occurring in the adult population, the drugs prescribed for their treatment are potassium channel blockers, cholinesterase inhibitors, immune therapy, intravenous immunoglobulin, plasmapheresis, etc.

The USFDA has recently approved amifampridine for the treatment of LEMS in children from 6 to 17 years of age. It has received orphan drug and fast-track designation status, which will proactively incentivize drug development for curing rare diseases.

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A significant rise in clinical research to cure orphan diseases and the domicile of major players together drive the market’s growth in the North American region.

North America is currently dominating the regional segment of the Lambert-Eaton myasthenic syndrome (LEMS) market, holding 39% of the market. The significant increase in clinical research activities to cure orphan diseases is one of the major factors responsible for its positive growth profile.

According to the Centers for Disease Control and Prevention (CDC), research findings indicate that approximately 3% of the patients suffering from small cell lung cancer (SCLC) suffer from Lambert-Eaton myasthenic syndrome (LEMS). The prevalence rate of SCLC in the United States is 5 cases per million people.

The dominance of major players such as Biomarin Pharmaceutical, Inc., Catalyst Pharmaceuticals, Inc., Merck & Co., Inc., etc., propels market growth in the North American region. Europe holds the second position, representing a market share of 34.5%, owing to the high incidence rate of LEMS in the European community. As per the research cited by the European LEMS Registry, the incidence rate is 0.48 to 0.75 per million people.

The low prevalence rate in comparison to the incidence rate is due to the poor survival of LEMS patients with paraneoplastic types of disease. Asia Pacific is currently holding 14% of the market, primarily due to the large patient population suffering from SCLC and proactive government initiatives in providing financial aid for the treatment of rare diseases.

Periods of History and Forecast

This research report presents the analysis of each segment from 2017 to 2027,considering 2018as the base year for the research. The compound annual growth rate (CAGR) for each of the respective segments is calculated for the forecast period from 2019 to 2027.

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Report Scope by Segments

The market is segmented by treatment and by geography.

Pharmaceutical manufacturers providing medications for the treatment of Lambert-Eaton myasthenic syndrome are Allergan, Plc., Biomarin Pharmaceutical, Inc., Catalyst Pharmaceuticals, Inc., F. Hoffman-La Roche Ltd., GlaxoSmithKline, Plc., Jacobus Pharmaceutical Company, Inc., Kawasumi Laboratories, Inc., Merck & Co., Inc., and Mitsubishi Pharma Corporation.

Key questions are answered in this report.

  • Which pharmaceutical companies are engaged in the treatment of LEMS?
  • What is the global prevalence rate of LEMS and its clinical manifestations that overlap with cancer?
  • A brief explanation of DROs associated with the LEMS market?
  • Which drug received the USFDA orphan drug designation and fast-track designation for the treatment of LEMS in children?
  • What is the incidence rate in developed countries such as Europe and North America?

Chapter 1. Preface
1.1. Report Scope and Description
1.1.1. Purpose of the Report
1.1.2. Target Audience
1.1.3. USP and Key Treatment
1.2. Research Scope
1.3. Research Methodology
1.3.1. Phase I-Secondary Research
1.3.2. Phase II-Primary Research
1.3.3. Approach Adopted
1.3.4. Top-down Approach
1.3.5. Bottom-up Approach
1.3.6. Phase III-Expert Panel Review
1.3.7. Assumptions
1.4. Market Segmentation

Chapter 2. Executive Summary
2.1. Global LEMS Market Portraiture
2.2. Global LEMS Market, by Treatment, 2018 (US$ Mn)
2.3. Global LEMS Market, by Geography, 2018 (US$ Mn)

Chapter 3. Lambert-Eaton Myasthenic Syndrome (LEMS) Market: Dynamics and Future Outlook
3.1. Market Overview
3.2. Drivers
3.3. Challenges
3.4. Opportunities
3.5. Attractive Investment Proposition, by Geography, 2018
3.6. Competitive Analysis: Global LEMS Market, by Key Players, 2018

Chapter 4. Global Lambert-Eaton Myasthenic Syndrome (LEMS) Market, by Treatment
4.1. Overview
4.2. Potassium Channel Blockers (Amifampridine)
4.3. Cholinesterase Inhibitor (Pyridostigmine)
4.4. Immune Therapy
4.5. Intravenous Immunoglobulin
4.6. Plasmapheresis

Chapter 5. Global Lambert-Eaton Myasthenic Syndrome (LEMS) Market, by Geography
5.1. Overview
5.2. North America LEMS Market Analysis, 2017 – 2027
5.2.1. North America LEMS Market, by Treatment, 2017 – 2027 (US$ Mn)
5.2.2. North America LEMS Market, by Country, 2017 – 2027 (US$ Mn)
5.2.2.1. U.S.
5.2.2.2. Canada
5.3. Europe LEMS Market Analysis, 2017– 2027
5.3.1. Europe LEMS Market, by Treatment, 2017 – 2027 (US$ Mn)
5.3.2. Europe LEMS Market, by Country/Region, 2017 – 2027 (US$ Mn)
5.3.2.1. U.K.
5.3.2.2. Germany
5.3.2.3. Rest of Europe
5.4. Asia Pacific LEMS Market Analysis, 2017 – 2027
5.4.1. Asia Pacific LEMS Market, by Treatment, 2017 – 2027 (US$ Mn)
5.4.2. Asia Pacific LEMS Market, by Country/Region, 2017 – 2027 (US$ Mn)
5.4.2.1. China
5.4.2.2. Japan
5.4.2.3. Rest of Asia Pacific
5.5. Latin America LEMS Market Analysis, 2017 – 2027
5.5.1. Latin America LEMS Market, by Treatment, 2017 – 2027 (US$ Mn)
5.5.2. Latin America LEMS Market, by Country/Region, 2017 – 2027 (US$ Mn)
5.5.2.1. Brazil
5.5.2.2. Mexico
5.5.2.3. Rest of Latin America
5.6. Middle East & Africa LEMS Market Analysis, 2017 – 2027
5.6.1. MEA LEMS Market, by Treatment, 2017 – 2027 (US$ Mn)
5.6.2. MEA LEMS Market, by Region, 2017– 2027 (US$ Mn)
5.6.2.1. GCC
5.6.2.2. Rest of MEA

Chapter 6. Company Profiles
6.1. Allergan, Plc.
6.1.1. Business Description
6.1.2. Financial Information (Subject to data availability)
6.1.3. Product Portfolio
6.1.4. News Coverage
6.2. Biomarin Pharmaceutical, Inc.
6.3. Catalyst Pharmaceuticals, Inc.
6.4. F. Hoffman-La Roche Ltd.
6.5. GlaxoSmithkline, Plc.
6.6. Jacobus Pharmaceutical Company, Inc.
6.7. Kawasumi Laboratories, Inc.
6.8. Merck & Co., Inc.
6.9. Mitsubishi Pharma Corporation
6.10. Novartis AG

List of Figures

FIG. 1 Lambert-Eaton Myasthenic Syndrome (LEMS) Market: Research Methodology
FIG. 2 LEMS: Market Segmentation
FIG. 3 Global LEMS Market, by Treatment, 2018 (US$ Mn)
FIG. 4 Global LEMS Market, by Geography, 2018 (US$ Mn)
FIG. 5 Attractive Investment Proposition: by Geography, 2018
FIG. 6 Competitive Analysis: Global LEMS Market, by Key Players, 2018
FIG. 7 Global Potassium Channel Blockers Market for LEMS, 2017 – 2027 (US$ Mn)
FIG. 8 Global Cholinesterase Inhibitor Market for LEMS, 2017 – 2027 (US$ Mn)
FIG. 9 Global Immune Therapy Market for LEMS, 2017 – 2027 (US$ Mn)
FIG. 10 Global Intravenous Immunoglobulin Market for LEMS, 2017– 2027 (US$ Mn)
FIG. 11 Global Plasmapheresis Market for LEMS, 2017 – 2027 (US$ Mn)
FIG. 12 U.S. LEMS Market, 2017 – 2027 (US$ Mn)
FIG. 13 Canada LEMS Market, 2017 – 2027 (US$ Mn)
FIG. 14 U.K. LEMS Market, 2017 – 2027 (US$ Mn)
FIG. 15 Germany LEMS Market, 2017 – 2027 (US$ Mn)
FIG. 16 Rest of Europe LEMS Market, 2017 – 2027 (US$ Mn)
FIG. 17 China LEMS Market, 2017– 2027 (US$ Mn)
FIG. 18 Japan LEMS Market, 2017 – 2027 (US$ Mn)
FIG. 19 Rest of Asia Pacific LEMS Market, 2017 – 2027 (US$ Mn)
FIG. 20 Brazil LEMS Market, 2017 – 2027 (US$ Mn)
FIG. 21 Mexico LEMS Market, 2017 – 2027 (US$ Mn)
FIG. 22 Rest of Latin America LEMS Market, 2017 – 2027 (US$ Mn)
FIG. 23 GCC LEMS Market, 2017 – 2027 (US$ Mn)
FIG. 24 Rest of Middle East and Africa LEMS Market, 2017 – 2027 (US$ Mn)

List of Tables

TABLE 1 Global Lambert-Eaton Myasthenic Syndrome (LEMS) Market Portraiture
TABLE 2 Global LEMS Market, by Treatment, 2017 – 2027 (US$ Mn)
TABLE 3 Global LEMS Market, by Geography, 2017 – 2027 (US$ Mn)
TABLE 4 North America LEMS Market, by Treatment, 2017 – 2027 (US$ Mn)
TABLE 5 North America LEMS Market, by Country, 2017 – 2027 (US$ Mn)
TABLE 6 Europe LEMS Market, by Treatment, 2017 – 2027 (US$ Mn)
TABLE 7 Europe LEMS Market, by Country/Region, 2017– 2027 (US$ Mn)
TABLE 8 Asia Pacific LEMS Market, by Treatment, 2017 – 2027 (US$ Mn)
TABLE 9 Asia Pacific LEMS Market, by Country/Region, 2017 – 2027 (US$ Mn)
TABLE 10 Latin America LEMS Market, by Treatment, 2017 – 2027 (US$ Mn)
TABLE 11 Latin America LEMS Market, by Country/Region, 2017 – 2027 (US$ Mn)
TABLE 12 Middle East and Africa LEMS Market, by Treatment, 2017– 2027 (US$ Mn)
TABLE 13 Middle East and Africa LEMS Market, by Region, 2017 – 2027 (US$ Mn)
TABLE 14 Allergan, Plc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 15 Biomarin Pharmaceutical, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 16 Catalyst Pharmaceuticals, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 17 F. Hoffman-La Roche Ltd.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 18 GlaxoSmithkline, Plc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 19 Jacobus Pharmaceutical Company, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 20 Kawasumi Laboratories, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 21 Merck & Co., Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 22 Mitsubishi Pharma Corporation: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 23 Novartis AG: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)

Frequently Asked Question:

What is the size of Lambert-Eaton Myasthenic Syndrome Market?

The market for Lambert-Eaton Myasthenic Syndrome Market is expected to reach USD$ XX in 2027.

What is the Lambert-Eaton Myasthenic Syndrome Market CAGR?

The Lambert-Eaton Myasthenic Syndrome Market is expected to see significant CAGR growth over the coming years, at 6.7%.

What is the Forecast period considered for Lambert-Eaton Myasthenic Syndrome Market?

The report is forecasted from 2019 -2027.

What is the base year considered for Lambert-Eaton Myasthenic Syndrome Market?

The base year of this report is 2018.

Who are the major players in this market?

Biomarin Pharmaceutical, Inc., Catalyst Pharmaceuticals, Inc., Merck & Co., Inc. are some of the major players in the global market.

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