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Bone Grafts And Substitutes Market By Application (Spinal Fusion, Long Bone, Foot And Ankle, Craniomaxillofacial, Joint Reconstruction, Dental), By Material (Bone Grafts Substitutes, Allografts) - Growth, Future Prospects, And Competitive Analysis, 2017 - 2025

This report on global bone grafts and substitutes studies the market in terms of various materials and applications. The market is driven by key factors such as an increase in the number of traumatic injuries and a rising geriatric population suffering from osteoporosis, rheumatoid arthritis, and periodontal diseases. Additionally, the increasing number of minimally invasive surgeries performed for complications such as disc herniation, burst fractures, etc., will have a positive influence on the growth of bone grafts and substitute products. The limiting factors related to this market are the immune response generated during surgical procedures, post-operative pain, and stringent regulatory guidelines regarding the approval of bone grafts and substitutes.

For the purpose of this study, the various materials studied were bone graft substitutes and allografts. Bone graft substitutes are further categorized into bone morphogenic proteins, synthetic bone grafts, and others. Allografts are subdivided further as demineralized bone matrix and others. Applications studied for the purpose of this research include spinal fusion, long bone, foot and ankle, craniomaxillofacial, joint reconstruction, and dental. Market size estimates and forecasts for these segments are provided in US$ Mn, along with the respective CAGRs for the period 2017-2025, using 2016 as the base year.

The geographic segmentation of the global bone grafts and substitutes market is performed for the regions of North America, Europe, Asia Pacific, Latin America, the Middle East, and Africa. Segments are provided in US$ Mn, along with the respective CAGRs for the period 2017-2025, using 2016 as the base year.

This report also includes qualitative assessment factors such as market dynamics (drivers, restraints, and opportunities) to have a good understanding of the current and anticipated trends in the global bone grafts and substitutes market. Market attractiveness assessment, Porter's five forces model, and competitive landscape analysis by key players are also presented in the study. Furthermore, this report concludes with a profile of key market players currently enjoying prominent positions in the global bone grafts and substitutes market. The major players in the global bone grafts and substitutes market are AlloSource, Baxter Healthcare Corporation, DePuy Synthes, Medtronic plc, NuVasive, Inc., Orthofix Holdings, Inc., Orthovita, Inc., Stryker Corporation, Smith & Nephew, Inc., and Wright Medical Group N.V.

Based on material, the global bone grafts and substitutes market is categorized into:

Substitutes for Bone Grafts

  • Bone Morphogenic Proteins (BMP)
  • Synthetic bone grafts
  • Others

Allografts

  • demineralized bone matrix
  • Others

The bone grafts and substitutes market is driven by key factors such as the rising prevalence of lumbar spine trauma, joint trauma, and craniomaxillofacial surgeries required due to an increase in road accidents, sports injuries, workplace injuries, falls, and violence; an increasing geriatric population with joint disorders; and an increasing number of minimally invasive procedures. Manufacturers involved in the production of bone grafts and substitutes are intensively focusing on imparting aesthetic values to their products, such as distinctive and versatile handling features that help the surgeon's techniques. Presently, allografts hold the largest market share due to key drivers such as the rising prevalence of traumatic bone injuries such as those to the spine, hips, knees, etc.; cost-efficient procedures due to a shorter hospital stay; a quick surgical procedure; and an early wound recovery period.

Bone graft substitutes show a promising sales forecast and will be the fastest-growing segment, primarily due to factors such as accelerated bone formation due to inherent features of bone substitutes, such as negative surface charge, increased protein fusion, enhanced cell attachment, and favorable natural remodeling and graft resorption. The major players in the bone grafts and substitutes market are AlloSource, Baxter Healthcare Corporation, DePuy Synthes, Medtronic plc, NuVasive, Inc., Orthofix Holdings, Inc., Orthovita, Inc., Stryker Corporation, Smith & Nephew, Inc., and Wright Medical Group N.V.

The bone graft and substitutes market is classified by application.

  • Spinal Fusion
  • Long Bone
  • Foot and ankle
  • Craniomaxillofacial
  • Joint Reconstruction
  • Dental

The ideal bone graft substitute should consist of the following essential features: an osteoconductive matrix, osteoinductive properties, and osteogenic cells. Autogenous cancellous bone grafting has been considered the gold standard in bone transplantation, but the limitations imposed were enhanced operative blood loss, donor site morbidity, and limited availability for harvest. Spinal fusion provides a lucrative market and dominates the market share due to factors such as the rising prevalence of low back disc herniation, burst fractures, osteoporosis, etc., and the increasing number of patients suffering from equine cauda syndrome who prefer spinal fusion surgeries to release pressure on many spinal nerves, which causes paralysis in the lower extremities.

Dental surgeries are anticipated to be the fastest growing market, primarily due to factors such as the rising prevalence of periodontal disease, vehicular accidents resulting in dental trauma resulting in loss of teeth and gums, causing deformation in outward cosmetic appearance, and dental bone grafting, which is also employed to maintain bone structure after tooth extraction. Dental implants also impart other benefits such as improved speech, convenience during eating, and improved oral health.

For the purpose of this study, the global market for bone grafts and substitutes is categorized into the following regional and country-specific markets:

North America

  • U.S.
  • Canada

Europe

  • U.K.
  • Germany
  • Rest of Europe

Asia Pacific

  • China
  • Japan
  • India
  • Rest of Asia Pacific

Latin America

  • Brazil
  • Mexico
  • rest of Latin America

Middle East and Africa

  • GCC
  • Rest of the Middle East and Africa

In 2016, North America was found to have the largest bone grafts and substitutes market. According to the Centers for Disease Control and Prevention 2013-14 survey, the prevalence of osteoporosis in the U.S. was 5.1% for men over 65 years of age and 24.5 % for women. The dominance of North America has mainly been attributed to the presence of key drivers such as the rising prevalence of traumatic accidents and osteoporosis, the existence of developed healthcare infrastructure with orthopedic facilities, and the domicile of key players pioneering the manufacture of bone grafts and substitutes.

The market growth in Europe is mainly attributed to an increase in the number of geriatric patients suffering from osteoporosis and periodontal diseases and the presence of manufacturers focusing on the research and development activities required to produce the next generation of bone grafts and substitutes. Asia Pacific is observed to be the fastest- growing regional segment throughout the forecast period of 2017–20255. The rising number of traumatic injuries caused by car accidents, violence, and sports injuries necessitating surgical procedures is expected to drive market growth in Asia Pacific; rising disposable incomes make healthcare services more affordable; a thriving e-commerce industry to promote sales and a supportive regulatory environment for bone grafts and substitutes. Moreover, factors such as developing healthcare infrastructure, health awareness campaigns to promote sales, and the establishment of subsidiaries by major players ie, untapped markets are going to fuel the rapid growth of the bone grafts and substitutes market in Latin America,the MiddleEast,t and Africa in the near future 

Frequently Asked Question:

The market for Bone Grafts And Substitutes Market is expected to reach USD$ 3,872.1 Mn in 2025.

The Bone Grafts And Substitutes Market is expected to see significant CAGR growth over the coming years, at 5.72 %.

The report is forecasted from 2017 -2025.

The base year of this report is 2016.

Baxter Healthcare Corporation, DePuy Synthes, Medtronic plc, NuVasive, Inc., Orthofix Holdings, Inc., Orthovita, Inc., Stryker Corporation, Smith & Nephew, Inc. are some of the major players in the global market.

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Godaddy
Published Date:  Nov 2017
Category:  Medical Devices
Report ID:   58802
Report Format:   PDF
Pages:   120
Rating:    4.6 (80)
Delivery Time: 24 Hours to 48 Hours   
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