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Degenerative Disc Disease - Pipeline Insights, Recent Developments, Major Players and Review

Degenerative Disc Disease: Overview

Degenerative disc disease (DDD) is a condition in which the core strength of the rear discs deteriorates. This condition develops over time due to wear and tear or an injury.

It's considered an illness condition in which your discs "degenerate," and eventually, they lose the ability to cushion the spine. In addition, because discs have a restricted blood supply, they can't quickly heal themselves once they've been harmed.

Cases of degenerative disc disease are relatively widespread across the globe, with almost 30% of adults who fall in the age group of 30 to 50 years primarily suffering from the disease. Although surgical complications are conceivable, the advantages of surgery usually outweigh the dangers.

However, damage to adjacent nerves and blood vessels, infection, and issues specific to the operation you need, such as problems with an artificial disc, are all possible risks.

Report Key Takeaways

Recommended Medications/Treatments for Degenerative Disc Disease:

Physical therapy

A physical therapist can help you know how to stretch and avoid muscle spasms and rebuild strength and improve posture. To relieve symptoms, heat and ice can be applied to the area of pain. In addition, swimming may be suggested as a kind of exercise for reducing spine pressure.

Decompression surgery

Various options for removing a portion of the disc's joint can reduce nerve strain. Other treatment may be required if the patient develops further complications such as a herniated disc, osteoarthritis, or spinal stenosis.

Stabilization surgery

This can be done anywhere along the spine, although the lower back and neck are the most common areas. This is because these sections of the spine move the most. This can relieve excruciating pain in individuals whose spines can no longer support their weight, but it can also hasten disc degeneration near fused vertebrae.

Recent Developments Related to Degenerative Disc Disease

BioRestorative Therapeutics, Inc., a clinical-stage firm specializing in stem cell-based therapies, has announced site recruitment for its Phase 2 clinical study for persistent lumbar disc degeneration (cLDD). The Phase 2 trial by BioRestorative is a randomized experiment to assess the excellent safety and preliminary efficacy associated with a single intradiscal injection of BRTX-100, the company's autologous investigational stem cell-based therapy.


Spine BioPharma, Inc. is a leading biopharmaceutical company explicitly working on the development of non-surgical therapeutics for the effective treatment of low back pain that is the result of degenerative disc degeneration. The company has recently announced its successful completion of $13 million Series B equity financing.


Major Players Working on Degenerative Disc Disease

Several dominant companies invest heavily in research and development to develop practical solutions to cure degenerative disc disease. Some leading companies are Biopharm gmbh, AnGes Inc., Bone Therapeutics SA, Ankasa Regenerative Therapeutics Inc., Cerapedics Inc., co., and BioRestorative Therapies Inc.

Key Reasons to Purchase This Report

  • A trend analysis includes a comparison of previous and current trends and estimates for future trends that are expected to impact the global landscape.
  • Accurate data and actual statistics on the history and current patient pool for the target condition and situation in all major nations worldwide.
  • The report discusses current treatment methods, performance analyses for each available therapy, and a geographical forecast for the condition under consideration.

Disc degeneration can manifest itself in a variety of ways, from no symptoms to excruciating pain that prevents an individual from carrying on with their everyday activities. The disorder begins with damage to the spine, but symptoms spread to other regions of the body over time.

Symptoms, when and where the pain occurs, if there is tingling or numbness, and which situations cause the most discomfort will all be discussed with the doctor. Muscle strength and nerve function are tested as part of a physical examination.

It's natural for us to start experiencing disc degeneration as we get older, but whether or not this results in back pain differs from person to person. Another reason you might have degenerative disc disease is if you've had previous or current injuries that have led to the degeneration.

Degenerative disc disease is hard to prevent in the early stage. However, you can take action to reduce your risk of issues by maintaining excellent posture, staying active, and quitting smoking.

Degenerative disc disease is more common in older adults since their spinal discs have been in use for a longer time. The discs in between each vertebra have had more time to wear down, similar to how joint cartilage wears out in osteoarthritis.

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Trusted By
Godaddy
Published Date:  Jul 2022
Category:  Healthcare
Report ID:   60589
Report Format:   PDF
Pages:   90
Rating:    4.8 (16)
Delivery Time: 24 Hours to 48 Hours   
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