Degenerative Disc Disease: Overview
Degenerative disc disease (DDD) is a condition in which the core strength of the rear discs deteriorates. This condition develops over time due to wear and tear or an injury.
It’s considered an illness condition in which your discs “degenerate,” and eventually, they lose the ability to cushion the spine. In addition, because discs have a restricted blood supply, they can’t quickly heal themselves once they’ve been harmed.
Cases of degenerative disc disease are relatively widespread across the globe, with almost 30% of adults who fall in the age group of 30 to 50 years primarily suffering from the disease. Although surgical complications are conceivable, the advantages of surgery usually outweigh the dangers.
However, damage to adjacent nerves and blood vessels, infection, and issues specific to the operation you need, such as problems with an artificial disc, are all possible risks.
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Recommended Medications/Treatments for Degenerative Disc Disease:
Physical therapy
A physical therapist can help you know how to stretch and avoid muscle spasms and rebuild strength and improve posture. To relieve symptoms, heat and ice can be applied to the area of pain. In addition, swimming may be suggested as a kind of exercise for reducing spine pressure.
Decompression surgery
Various options for removing a portion of the disc’s joint can reduce nerve strain. Other treatment may be required if the patient develops further complications such as a herniated disc, osteoarthritis, or spinal stenosis.
Stabilization surgery
This can be done anywhere along the spine, although the lower back and neck are the most common areas. This is because these sections of the spine move the most. This can relieve excruciating pain in individuals whose spines can no longer support their weight, but it can also hasten disc degeneration near fused vertebrae.
Recent Developments Related to Degenerative Disc Disease
BioRestorative Therapeutics, Inc., a clinical-stage firm specializing in stem cell-based therapies, has announced site recruitment for its Phase 2 clinical study for persistent lumbar disc degeneration (cLDD). The Phase 2 trial by BioRestorative is a randomized experiment to assess the excellent safety and preliminary efficacy associated with a single intradiscal injection of BRTX-100, the company’s autologous investigational stem cell-based therapy.
Spine BioPharma, Inc. is a leading biopharmaceutical company explicitly working on the development of non-surgical therapeutics for the effective treatment of low back pain that is the result of degenerative disc degeneration. The company has recently announced its successful completion of $13 million Series B equity financing.
Major Players Working on Degenerative Disc Disease
Several dominant companies invest heavily in research and development to develop practical solutions to cure degenerative disc disease. Some leading companies are Biopharm gmbh, AnGes Inc., Bone Therapeutics SA, Ankasa Regenerative Therapeutics Inc., Cerapedics Inc., co., and BioRestorative Therapies Inc.
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- A trend analysis includes a comparison of previous and current trends and estimates for future trends that are expected to impact the global landscape.
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- The report discusses current treatment methods, performance analyses for each available therapy, and a geographical forecast for the condition under consideration.