Epigenetics Market

Market Insights

Epigenetics is a term referring to the study of long-term changes in gene expression that may or may not be heritable and do not involve changes to the DNA sequence. It is estimated that the epigenetics market will grow at a double-digit CAGR over the forecast period from 2018 to 2026. Some major factors assisting the market’s growth are increasing awareness about epigenetics in different medical fields, growing to fund for research and development activities, and the increasing prevalence of complex diseases such as cancer. Conversely, the scarcity of skilled professionals and the existence of a strict regulatory framework governing the field of epigenetics and genetic research limit market growth.

The global epigenetics market is classified on the basis of products, technologies, and applications. This report study includes the market estimation and forecast analysis for each of these classes for the period from 2016 to 2026, as well as respective CAGRs for the forecast period from 2018 to 2026. On the basis of product types, the epigenetics market is categorized as kits (ChiP-Seq kits, whole-genome amplification kits, 5-HMC, and 5-MC analysis kits, and other epigenetics kits), reagents, enzymes (DNA-modifying enzymes, protein-modifying enzymes, and RNA-modifying enzymes), instruments, and bioinformatics tools. Based on applications, this market is segmented as cancer, metabolic diseases, immune diseases, cardiovascular diseases, and other applications. DNA methylation, histone modification, and other techniques are the technologies studied in this report.

The global epigenetics market report also studies the following regional markets:

• North America

• • U.S.
  • Canada
• Europe
  • U.K.
  • Germany
  • Rest of Europe
• Asia Pacific
  • Japan
  • China
  • Rest of Asia Pacific
• Latin America
  • Brazil
  • Mexico
  • rest of Latin America
• Middle East and Africa
  • GCC
  • the remainder of MEA

Alongside the numeric data (market size and forecast), subjective informational sets and assessment tools are also incorporated in this report to provide an in-depth analysis of general market circumstances and future projections. Information such as epigenetics market drivers, challenges, and opportunities covers insights related to current trends in the global epigenetics market. Attractive investment propositions, company profiles, and market positioning of key manufacturers provide insights into the global epigenetics market’s competitive situation. This report also presents a company profiles segment, which features key data related to the prominent players involved in the epigenetics market.

Based on the product types, the global epigenetics market is segmented as follows:

Kits

• ChiP-Seq Kits
• Whole-Genome Amplification Kits
• 5-HMC and 5-MC Analysis Kits
• other epigenetics kits

Reagents

• Enzymes
• DNA-Modifying Enzymes
• Protein-Modifying Enzymes
• RNA-Modifying Enzymes
• Instruments
• Bioinformatics Tools

Epigenetics refers to heritable changes in genetic modifications that do not involve changes to the primary DNA sequence; it is important in gene expression. Epigenetic changes are regular and naturally occurring; however, several factors, such as lifestyle, disease state, nutrition, age, environment, etc., may lead to epigenetic changes. The global epigenetics market is expected to witness rewarding development over the forecast period owing to the increasing importance of epigenetics to understanding mechanisms of human development, aging, and the origins of different forms of disease such as cancer, mental illness, heart disease, and several others. Currently, the demand for kits is the highest in the market and will also undergo the fastest market growth over the forecast period, primarily due to the following: continuous advancement in the nature and precision of kits; wide availability of robust, simple-to-use, and cost-efficient kits; and increasing adoption from research laboratories. Furthermore, enormous investments in R&D, an increase in the prevalence of several life-threatening diseases, and increased government funding for life science research are other factors propelling the growth of the epigenetics kits market globally.

The global epigenetics market is divided into the following applications:

• Cancer
• Metabolic Diseases
• Immune Diseases
• Cardiovascular Diseases
• Others

Since the last few decades, the demand for epigenetics studies in the characterization of various diseases has increased in the fields of drug discovery and life science research. The applicability of epigenetic studies for complex diseases such as cancer, behavior plasticity, autoimmune diseases, neurodegenerative and psychological disorders, addiction, etc., has considerably increased in the market. In 2017, cancer was the major revenue-generating segment in the global epigenetics market because of the reported evidence that epigenetic modifications have a considerable effect on cancer development and, therefore, management. The non-oncology segment of the epigenetics market comprises metabolic diseases, infectious diseases, cardiovascular diseases, and others. Metabolic diseases were the largest share-holding sub-segment in the year 2014 at over 32.0% due to the high impact of a high-fat diet on DNA modifications and epigenetic regulation of metabolism.

However, the cardiovascular disorders segment is expected to be the fastest-growing segment over the forecast period owing to the emergence of technologies such as microRNA modifications in the diagnosis and treatment of cardiovascular disorders. Other factors, such as rising cancer prevalence, a robust product pipeline, and a greater number of unmet needs, are fueling the growth of epigenetics in cancer.

Based on the technology types, the global epigenetics market is segmented as follows:

• DNA Methylation
• Histone Modification
• Other Techniques

Epigenetics is the study of modifications in gene expression that do not involve changes to the genetic code. The epigenetics market will grow significantly over the forecast period owing to its robustness. Furthermore, the growing use of epigenetics in targeted therapy and personalized medicine will have an impact on market growth over the forecast period.DNA methylation, non-coding RNA-associated gene silencing, and histone modification play an essential role in initiating and sustaining epigenetic changes. Some of the factors contributing to its largest share include the introduction of technological advancements such as methylation-sensitive PCR (MSP) and the rapid adoption of these products to improve diagnostic efficiency. It is observed that the demand for DNA methylation techniques is the highest in the market as it is a rapid and accurate technique for whole genome analysis. The DNA methylation technique is used to prepare DNA for methylation analysis; it includes methylated DNA selection, enzymatic compartmentalization by methylation-sensitive enzymes, and biochemical treatment of the DNA. The DNA methylation technique has enormous potential for understanding the functional mechanisms of complex diseases and developing personalized drugs. Moreover, methylation plays a fundamental role in cell divisions, differentiation, apoptosis, growth factor response, detoxification, metastasis, etc., which have promoted huge advances in the early detection of cancer.

Chapter 1. Preface
1.1. Report Description
1.1.1. Purpose of the Report
1.1.2. Target Audience
1.1.3. USP and Key Offerings
1.2. Research Scope
1.3. Research Methodology
1.3.1. Phase I-Secondary Research
1.3.2. Phase II-Primary Research
1.3.3. Phase III-Expert Panel Review
1.3.4. Assumptions

Chapter 2. Executive Summary
2.1. Global Epigenetics Market Portraiture
2.2. Global Epigenetics Market, by Product, 2017 (US$ Mn)
2.3. Global Epigenetics Market, by Technology, 2017 (US$ Mn)
2.4. Global Epigenetics Market, by Application, 2017 (US$ Mn)
2.5. Global Epigenetics Market, by Geography, 2017 (US$ Mn)

Chapter 3. Epigenetics: Market Dynamics and Outlook
3.1. Market Definition and Overview
3.2. Market Dynamics
3.2.1. Drivers
3.2.2. Challenges
3.2.3. Opportunities
3.3. Attractive Investment Proposition: Epigenetics Market, by Geography, 2017
3.4. Competitive Analysis of Key Players in Epigenetics Market, 2017

Chapter 4. Global Epigenetics Market, by Product, 2016 – 2026 (US$ Mn)
4.1. Overview
4.2. Kits
4.2.1. ChiP-Seq Kits
4.2.2. Whole-Genome Amplification Kits
4.2.3. 5-HMC and 5-MC Analysis Kits
4.2.4. Other Epigenetics Kits
4.3. Reagents
4.4. Enzymes
4.4.1. DNA-Modifying Enzymes
4.4.2. Protein-Modifying Enzymes
4.4.3. RNA-Modifying Enzymes
4.5. Instruments
4.6. Bioinformatics Tools

Chapter 5. Global Epigenetics Market, by Technology, 2016 – 2026 (US$ Mn)
5.1. Overview
5.2. DNA Methylation
5.3. Histone Modification
5.4. Other Techniques

Chapter 6. Global Epigenetics Market, by Application, 2016 – 2026 (US$ Mn)
6.1. Overview
6.2. Cancer
6.3. Metabolic Diseases
6.4. Immune Diseases
6.5. Cardiovascular Diseases
6.6. Others

Chapter 7. Global Epigenetics Market, by Geography, 2016 – 2026 (US$ Mn)
7.1. Overview
7.2. North America Epigenetics Market, 2016 – 2026 (US$ Mn)
7.2.1. North America Epigenetics Market, by Product, 2016 – 2026 (US$ Mn)
7.2.2. North America Epigenetics Market, by Technology, 2016 – 2026 (US$ Mn)
7.2.3. North America Epigenetics Market, by Application, 2016 – 2026 (US$ Mn)
7.2.4. North America Epigenetics Market, by Country, 2016 – 2026 (US$ Mn)
7.2.4.1. U.S.
7.2.4.2. Canada
7.3. Europe Epigenetics Market, 2016 – 2026 (US$ Mn)
7.3.1. Europe Epigenetics Market, by Product, 2016 – 2026 (US$ Mn)
7.3.2. Europe Epigenetics Market, by Technology, 2016 – 2026 (US$ Mn)
7.3.3. Europe Epigenetics Market, by Application, 2016 – 2026 (US$ Mn)
7.3.4. Europe Epigenetics Market, by Country, 2016 – 2026 (US$ Mn)
7.3.4.1. U.K.
7.3.4.2. Germany
7.3.4.3. Rest of Europe
7.4. Asia Pacific Epigenetics Market, 2016 – 2026 (US$ Mn)
7.4.1. Asia Pacific Epigenetics Market, by Product, 2016 – 2026 (US$ Mn)
7.4.2. Asia Pacific Epigenetics Market, by Technology, 2016 – 2026 (US$ Mn)
7.4.3. Asia Pacific Epigenetics Market, by Application, 2016 – 2026 (US$ Mn)
7.4.4. Asia Pacific Epigenetics Market, by Country, 2016 – 2026 (US$ Mn)
7.4.4.1. China
7.4.4.2. Japan
7.4.4.3. Rest of APAC
7.5. Latin America Epigenetics Market, 2016 – 2026 (US$ Mn)
7.5.1. Latin America Epigenetics Market, by Product, 2016 – 2026 (US$ Mn)
7.5.2. Latin America Epigenetics Market, by Technology, 2016 – 2026 (US$ Mn)
7.5.3. Latin America Epigenetics Market, by Application, 2016 – 2026 (US$ Mn)
7.5.4. Latin America Epigenetics Market, by Country, 2016 – 2026 (US$ Mn)
7.5.4.1. Brazil
7.5.4.2. Mexico
7.5.4.3. Rest of Latin America
7.6. Middle East & Africa (MEA) Epigenetics Market, 2016 – 2026 (US$ Mn)
7.6.1. Middle East and Africa Epigenetics Market, by Product, 2016 – 2026 (US$ Mn)
7.6.2. Middle East and Africa Epigenetics Market, by Technology, 2016 – 2026 (US$ Mn)
7.6.3. Middle East and Africa Epigenetics Market, by Application, 2016 – 2026 (US$ Mn)
7.6.4. Middle East and Africa Epigenetics Market, by Region, 2016 – 2026 (US$ Mn)
7.6.4.1. GCC
7.6.4.2. Rest of MEA

Chapter 8. Company Profiles
8.1. Abcam, Plc.
8.1.1. Business Description
8.1.2. Financial Information (Subject to data availability)
8.1.3. Product Type Portfolio
8.1.4. Key Developments
8.2. Active Motif, Inc.
8.3. Agilent Technologies, Inc.
8.4. Bio-Rad Laboratories, Inc.
8.5. Diagenode, Inc.
8.6. Illumina, Inc.
8.7. Merck & Co., Inc.
8.8. New England Biolabs, Inc.
8.9. Perkinelmer, Inc.
8.10. Qiagen N.V.
8.11. Thermo Fisher Scientific, Inc.
8.12. Zymo Research Corp.

List of Figures

FIG. 1 Epigenetics: Market Segmentation
FIG. 2 Global Epigenetics Market, by Product, 2017 (US$ Mn)
FIG. 3 Global Epigenetics Market, by Technology, 2017 (US$ Mn)
FIG. 4 Global Epigenetics Market, by Application, 2017 (US$ Mn)
FIG. 5 Global Epigenetics Market, by Geography, 2017 (US$ Mn)
FIG. 6 Attractive Investment Proposition, by Geography
FIG. 7 Market Competition Landscape, by Key Players, 2017
FIG. 8 Global ChiP-Seq Kits Market, 2016 – 2026 (US$ Mn)
FIG. 9 Global Whole-Genome Amplification Kits Market, 2016 – 2026 (US$ Mn)
FIG. 10 Global 5–HMC and 5-MC Analysis Kits Market, 2016 – 2026 (US$ Mn)
FIG. 11 Global Other Epigenetics Kits Market, 2016 – 2026 (US$ Mn)
FIG. 12 Global Reagents Market in Epigenetics, 2016 – 2026 (US$ Mn)
FIG. 13 Global DNA Modifying Enzymes Market in Epigenetics, 2016 – 2026 (US$ Mn)
FIG. 14 Global Protein Modifying Enzymes Market in Epigenetics, 2016 – 2026 (US$ Mn)
FIG. 15 Global RNA Modifying Enzymes Market in Epigenetics, 2016 – 2026 (US$ Mn)
FIG. 16 Global Instruments Market in Epigenetics, 2016 – 2026 (US$ Mn)
FIG. 17 Global Bioinformatics Tools Market in Epigenetics, 2016 – 2026 (US$ Mn)
FIG. 18 Global DNA Methylation Market in Epigenetics, 2016 – 2026 (US$ Mn)
FIG. 19 Global Histone Modification Market in Epigenetics, 2016 – 2026 (US$ Mn)
FIG. 20 Global Other Techniques Market for Epigenetics in Epigenetics, 2016 – 2026 (US$ Mn)
FIG. 21 Global Epigenetics Market for Cancer, 2016 – 2026 (US$ Mn)
FIG. 22 Global Epigenetics Market for Metabolic Diseases, 2016 – 2026 (US$ Mn)
FIG. 23 Global Epigenetics Market for Immune Diseases, 2016 – 2026 (US$ Mn)
FIG. 24 Global Epigenetics Market for Cardiovascular Diseases, 2016 – 2026 (US$ Mn)
FIG. 25 Global Epigenetics Market for Other Applications, 2016 – 2026 (US$ Mn)
FIG. 26 U.S. Epigenetics Market, 2016 – 2026 (US$ Mn)
FIG. 27 Canada Epigenetics Market, 2016 – 2026 (US$ Mn)
FIG. 28 U.K. Epigenetics Market, 2016 – 2026 (US$ Mn)
FIG. 29 Germany Epigenetics Market, 2016 – 2026 (US$ Mn)
FIG. 30 Rest of Europe Epigenetics Market, 2016 – 2026 (US$ Mn)
FIG. 31 Japan Epigenetics Market, 2016 – 2026 (US$ Mn)
FIG. 32 China Epigenetics Market, 2016 – 2026 (US$ Mn)
FIG. 33 Rest of Asia Pacific Epigenetics Market, 2016 – 2026 (US$ Mn)
FIG. 34 Brazil Epigenetics Market, 2016 – 2026 (US$ Mn)
FIG. 35 Mexico Epigenetics Market, 2016 – 2026 (US$ Mn)
FIG. 36 Rest of Latin America Epigenetics Market, 2016 – 2026 (US$ Mn)
FIG. 37 GCC Epigenetics Market, 2016 – 2026 (US$ Mn)
FIG. 38 Rest of Middle East and Africa Epigenetics Market, 2016 – 2026 (US$ Mn)

List of Tables

TABLE 1 Global Epigenetics Market, by Product, 2016 – 2026 (US$ Mn)
TABLE 2 Global Epigenetics Market, by Technology, 2016 – 2026 (US$ Mn)
TABLE 3 Global Epigenetics Market, by Application, 2016 – 2026 (US$ Mn)
TABLE 4 North America Epigenetics Market, by Product, 2016 – 2026 (US$ Mn)
TABLE 5 North America Epigenetics Market, by Technology, 2016 – 2026 (US$ Mn)
TABLE 6 North America Epigenetics Market, by Application, 2016 – 2026 (US$ Mn)
TABLE 7 North America Epigenetics Market, by Country, 2016 – 2026 (US$ Mn)
TABLE 8 Europe Epigenetics Market, by Product, 2016 – 2026 (US$ Mn)
TABLE 9 Europe Epigenetics Market, by Technology, 2016 – 2026 (US$ Mn)
TABLE 10 Europe Epigenetics Market, by Application, 2016 – 2026 (US$ Mn)
TABLE 11 Europe Epigenetics Market, by Country, 2016 – 2026 (US$ Mn)
TABLE 12 Asia Pacific Epigenetics Market, by Product, 2016 – 2026 (US$ Mn)
TABLE 13 Asia Pacific Epigenetics Market, by Technology, 2016 – 2026 (US$ Mn)
TABLE 14 Asia Pacific Epigenetics Market, by Application, 2016 – 2026 (US$ Mn)
TABLE 15 Asia Pacific Epigenetics Market, by Country, 2016 – 2026 (US$ Mn)
TABLE 16 Latin America Epigenetics Market, by Product, 2016 – 2026 (US$ Mn)
TABLE 17 Latin America Epigenetics Market, by Technology, 2016 – 2026 (US$ Mn)
TABLE 18 Latin America Epigenetics Market, by Application, 2016 – 2026 (US$ Mn)
TABLE 19 Latin America Epigenetics Market, by Country, 2016 – 2026 (US$ Mn)
TABLE 20 Middle East and Africa Epigenetics Market, by Product, 2016 – 2026 (US$ Mn)
TABLE 21 Middle East and Africa Epigenetics Market, by Technology, 2016 – 2026 (US$ Mn)
TABLE 22 Middle East and Africa Epigenetics Market, by Application, 2016 – 2026 (US$ Mn)
TABLE 23 Middle East and Africa Epigenetics Market, by Country, 2016 – 2026 (US$ Mn)
TABLE 24 Abcam, Plc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Development)
TABLE 25 Active Motif, Inc. : Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Development)
TABLE 26 Agilent Technologies, Inc. : Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Development)
TABLE 27 Bio-Rad Laboratories, Inc. : Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Development)
TABLE 28 Diagenode, Inc. : Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Development)
TABLE 29 Illumina, Inc. : Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Development)
TABLE 30 Merck & Co., Inc. : Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Development)
TABLE 31 New England Biolabs, Inc. : Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Development)
TABLE 32 Perkinelmer, Inc. : Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Development)
TABLE 33 Qiagen N.V. : Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Development)
TABLE 34 Thermo Fisher Scientific, Inc. : Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Development)
TABLE 35 Zymo Research Corp. : Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Development)