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Cell Free Protein Expression Market By Product Type (E.Coli Cell-Free Protein Expression System, Rabbit Reticulocytes Cell-Free Protein Expression System, Wheat Germ Cell-Free Protein Expression System, Insect Cells Cell-Free Protein Expression System & Others), By Application Type (Enzyme Engineering, Protein Labeling, Protein-Protein Interaction & Others), By Expression Mode Type(Continuous Flow Expression, Batch Expression) – Growth, Share, Opportunities & Competitive Analysis, 2017-2025

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Published: | Report ID: 3175 | Report Format : PDF

Market Insights

For decades, the cell-free protein expression method has been used for the analysis of proteins. The most commonly used lysates include wheat germ or reticulocyte lysates. There is a tremendous improvement in E. coli and wheat germ-derived cell-free systems. The increased commercialization interest of biotechnology and biopharmaceutical companies (Qiagen, Roche, Novagen, and Invitrogen) in these tools has resulted in the growth of the cell-free protein expression market. A surge in research and development activities, increased interest in genomics and proteomics, and demand for biologics are some of the key factors propelling the growth of the cell-free protein expression market. However, one hindrance to using cell-free systems is the low yield of target proteins.

The report titled “Cell-Free Protein Expression Market: Growth, Future Prospects, and Competitive Analysis, 2017–2025” offers strategic insights into the overall cell-free protein expression market, along with the market size and estimates for the duration of 2015–2025. The said research study covers an in-depth analysis of multiple market segments based on the type of product, application, expression mode, and different geographies. The product types studied for analyzing the overall global cell-free protein expression market are majorly segmented into E. coli cell-free protein expression systems, rabbit reticulocytes cell-free protein expression systems, wheat germ cell-free protein expression systems, insect cells cell-free protein expression systems, mammalian cell-free protein expression systems, and consumables. The global cell-free protein expression market is segmented by application type into polyurethane, polyurethane/polycarbonate, and silicone. It is also segmented by expression mode into continuous flow expression and batch expression.

Geographically, the global cell-free protein expression market is studied for the following regional markets:

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • France
    • Italy
    • U.K.
    • Russia
    • Rest of Europe
  • Asia-Pacific
    • India
    • China
    • Japan
    • Rest of Asia-Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East and Africa
    • GCC Countries
    • South Africa
    • Rest of Middle East and Africa

The market size and forecast for these regional and country-level markets are presented in this study for the period 2015–2025. Market growth rates for the forecast period 2017–2025 are also included in this report, considering 2016 as the base year.

Along with quantitative information, qualitative information sets and assessment tools are provided in this study for a better analysis of the overall market scenario and future prospects. Information such as market inclination insights and drivers, challenges, and opportunities assists the readers in understanding the ongoing trends in the global cell-free protein expression market. Tools such as key player market positioning and appealing investment propositions provide readers with insights into the global cell-free protein expression market’s competitive scenario. This report concludes with a company profiles section that highlights major information about the key players engaged in the global cell-free protein expression market. In-depth competitive environment analysis and historical (2015) market size data are also provided in the report.

Based on the type of product, the global cell-free protein expression market is segmented as follows:

  • E. coli cell-free protein expression system
  • Cell-Free Protein Expression System for Rabbit Reticulocytes
  • Wheat Germ Cell-free Protein Expression System
  • Insect Cells Cell-free Protein Expression System
  • Mammalian cell-free protein expression system
  • Consumables
  • Labeling Tags
  • Vectors

coli lysate is the most simple and well-established cell-free protein expression system for the high-yield production of prokaryotic proteins. In eukaryotic systems, the most widely used is the rabbit reticulocyte lysate (RRL) cell-free protein expression system. It is more efficient and reduces the probability of error when compared with the E. coli system. White germ lysate is another eukaryotic expression system that is popularly used, yields higher output compared to other eukaryotic systems, and is used for large protein expression methods. Insect cell lysate is also used for large-size protein expression. Because they are the most preferred method for producing human proteins, mammalian cell-free protein expression methods are expected to be the fastest-growing segment of the cell protein expression market. The rising demand for biologics and proteomics research and its application in human drug discovery is the driving factor for the growth of the mammalian cell-free protein expression system market.

Based on the type of application, the global cell-free protein expression market is segmented as follows:

  • Enzyme Engineering
  • Protein Labeling
  • Protein-Protein interaction
  • Protein Purification

Currently, cell-free protein expression is one of the most lucrative markets, with a high adoption rate by the biopharmaceutical and biotechnological industries. It is being widely used in high-throughput functional proteomics and genomics. Protein-protein interaction segments occupy the largest share of the cell-free protein market. There is also significant growth observed in the research and development of protein production and the generation of protein libraries, which contribute to the fast growth of the protein-protein interaction segment.

Based on the type of expression mode, the global cell-free protein expression market is segmented as follows:

  • Expression of continuous flow
  • Batch Expression

Conventionally, batch expression was used for the synthesis of target proteins, as it is an easy-to-handle, fast, and reliable source for protein synthesis. A novel technique, the continuous flow expression system, is used for the synthesis of both prokaryotic and eukaryotic proteins. Continuous-Exchange Cell-Free (CECF) protein synthesis systems yield better protein when compared with batch reactions. Thus, continuous flow expression systems account for a large share of the cell-free protein expression market, and they are expected to grow in the forecast period.

For the purpose of this study, the global cell-free protein expression market is geographically categorized into:

  • North America (U.S., Canada)
  • Europe (UK, Germany, and the rest of Europe)
  • Asia Pacific (China, Japan, and the Rest of Asia)
  • Latin America (LATAM)
  • Middle East and Africa (MEA)

Cell-free protein expression has emerged as a potent new technology that is constantly improving and expanding. Due to advances in CFPE, it is possible to scale protein synthesis from a small scale to a manufacturing scale, which has inspired applications in genomics and structural biology, personalized medicine, and proteomic industrial applications. At present, North America dominates the global cell-free protein expression market, followed by the European market. Huge investments in research and development and rising demand for protein synthesis are the main drivers for the growth of the cell protein fusion market. North America and Europe together occupy more than half of the global cell-free protein expression market. Asia-Pacific is anticipated to be the fastest-growing cell-free protein expression market. Rising R&D activities increased funding from the government and biopharmaceutical and biotechnology companies, and increased demand for protein synthesis are driving growth in emerging markets such as China and India.

Chapter 1 Preface
1.1 Report Description
1.1.1 Purpose of the Report
1.1.2 Target Audience
1.1.3 USP and Key Offerings
1.2 Research Scope
1.3 Research Methodology
1.3.1 Phase I – Secondary Research
1.3.2 Phase II – Primary Research
1.3.3 Phase III – Expert Panel Review
1.3.4 Assumptions

Chapter 2 Executive Summary
2.1 Global Cell-free Protein Expression Market Portraiture
2.2 Global Cell-free Protein Expression Market Share, by Product type, 2016 (US$)
2.3 Global Cell-free Protein Expression Market Share, by Application type, 2016  (US$)
2.4 Global Cell-free Protein Expression Market Share, by Expression mode type, 2016  (US$)
2.5 Global Cell-free Protein Expression Market, by Geography, 2016 (Value %)

Chapter 3 Global Cell-free Protein Expression Market Analysis
3.1 Global Cell-free Protein Expression Market Overview
3.2 Market Dynamics
3.2.1 Market Drivers
3.2.2 Challenges
3.2.3 Opportunities
3.3 Attractive Investment Proposition
3.4 Competitive Landscape of Key Players in Cell-free Protein Expression Market

Chapter 4 Global Cell-free Protein Expression Market Analysis, by Product Type, 2015-2025 (US$ Mn)
4.1 Introduction
4.2 E.coli Cell-free Protein Expression System
4.3 Rabbit Reticulocytes Cell-free Protein Expression System
4.4 Wheat Germ Cell-free Protein Expression System
4.5 Insect Cells Cell-free Protein Expression System
4.6 Mammalian Cell-free Protein Expression System
4.7 Consumables
4.8 Labelling Tags
4.9 Vectors

Chapter 5 Global Cell-free Protein Expression Market Analysis, by Application Type, 2015-2025 (US$ Mn)
5.1 Introduction
5.2 Enzyme Engineering
5.3 Protein Labeling
5.4 Protein-Protein interaction
5.5 Protein Purification

Chapter 6 Global Cell-free Protein Expression Market Analysis, by Expression mode Type, 2015-2025 (US$ Mn)
6.1 Introduction
6.2 Continuous flow Expression
6.3 Batch Expression

Chapter 7 Global Cell-free Protein Expression Market, By Geography, 2015-2025 (US$ Mn)
7.1 Preface
7.2 North America (U.S. & Canada)
7.3 Europe (U.K., Germany & Rest of Europe)
7.4 Asia Pacific (China, Japan, and Rest of APAC)
7.5 Latin America (Brazil, Mexico and Rest of LATAM)
7.6 Middle East and Africa (UAE, Saudi Arabia, South Africa)

Chapter 8 Company Profiles
8.1 Bioneer Corporation
8.2 Biotechrabbit GmbH,
8.3 CellFree Sciences Co.
8.4 Cube Biotech GmbH
8.5 GeneCopoeia, Inc.
8.6 Jena Bioscience GmbH
8.7 New England Biolabs
8.8 Promega Corporation
8.9 Takara Bio,Inc
8.10 Thermo Fisher Scientific

List of Figures

FIG. 1 Global Cell-free Protein Expression Market: Research Methodology
FIG. 2 Global Cell-free Protein Expression Market Share, by Product type, 2016 (US$)
FIG. 3 Global Cell-free Protein Expression Market Share, by Application type, 2016 (US$)
FIG. 4 Global Cell-free Protein Expression Market Share, by Expression mode type, 2016 (US$)
FIG. 5 Global Cell-free Protein Expression Market, by Geography, 2016 (Value %)
FIG. 6 Attractive Investment Proposition: Global Cell-free Protein Expression Market, by Geography
FIG. 7 Competitive Analysis: Key Players in Global Cell-free Protein Expression Market
FIG. 8 Global E.coli Cell-free Protein Expression System Market, 2015 – 2025 (US$ Mn)
FIG. 9 Global Rabbit Reticulocytes Cell-free Protein Expression System Market, 2015 – 2025 (US$ Mn)
FIG. 10 Global Wheat Germ Cell-free Protein Expression System Market, 2015 – 2025 (US$ Mn)
FIG. 11 Global Insect Cells Cell-free Protein Expression System Market, 2015 – 2025 (US$ Mn)
FIG. 12 Global Mammalian Cell-free Protein Expression System Market, 2015 – 2025 (US$ Mn)
FIG. 13 Global Consumables Market, 2015 – 2025 (US$ Mn)
FIG. 14 Global Labelling Tags Market, 2015 – 2025 (US$ Mn)
FIG. 15 Global Vectors Market, 2015 – 2025 (US$ Mn)
FIG. 16 Global Enzyme Engineering Market, 2015 – 2025 (US$ Mn)
FIG. 17 Global Protein Labeling Market, 2015 – 2025 (US$ Mn)
FIG. 18 Global Protein-Protein interaction Market, 2015 – 2025 (US$ Mn)
FIG. 19 Global Protein Purification Market, 2015 – 2025 (US$ Mn)
FIG. 20 Global Continuous flow Expression Market, 2015 – 2025 (US$ Mn)
FIG. 21 Global Batch Expression Market, 2015 – 2025 (US$ Mn)
FIG. 22 Latin America Cell-free Protein Expression Market, 2015 – 2025 (US$ Mn)
FIG. 23 Middle East & Africa Cell-free Protein Expression Market, 2015 – 2025 (US$ Mn)

List of Tables

TABLE 1 Global Cell-free Protein Expression Market, By Product Type 2015-2025 (US$ Mn)
TABLE 2 Global Cell-free Protein Expression Market, By Application Type 2015-2025 (US$ Mn)
TABLE 3 Global Cell-free Protein Expression Market, By Expression mode Type 2015-2025 (US$ Mn)
TABLE 4 Global Cell-free Protein Expression Market, by Geography, 2015 – 2025 (US$ Mn)
TABLE 5 North America Cell-free Protein Expression Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 6 Europe Cell-free Protein Expression Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 7 Asia-Pacific Cell-free Protein Expression Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 8 Bioneer Corporation: Company Snapshot (Business Description; Financial Performance; Product Portfolio; News Coverage)
TABLE 9 Biotechrabbit GmbH,: Company Snapshot (Business Description; Financial Performance; Product Portfolio; News Coverage)
TABLE 10 CellFree Sciences Co.: Company Snapshot (Business Description; Financial Performance; Product Portfolio; News Coverage)
TABLE 11 Cube Biotech GmbH: Company Snapshot (Business Description; Financial Performance; Product Portfolio; News Coverage)
TABLE 12 GeneCopoeia, Inc.: Company Snapshot (Business Description; Financial Performance; Product Position Portfolio; News Coverage)
TABLE 13 Jena Bioscience GmbH: Company Snapshot (Business Description; Financial Performance; Product Portfolio; News Coverage)
TABLE 14 New England Biolabs: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 15 Promega Corporation: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 16 Takara Bio,Inc: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 17 Thermo Fisher Scientific: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)

Frequently Asked Questions

What is the size of Cell Free Protein Expression Market?

The market for Cell Free Protein Expression Market is expected to reach US$ 282.3 Mn By 2025.

What is the Cell Free Protein Expression Market CAGR?

The Cell Free Protein Expression Market is expected to see significant CAGR growth over the coming years, at 5.9%.

What is the Forecast period considered for Cell Free Protein Expression Market?

The report is forecasted from 2017-2025.

What is the base year considered for Cell Free Protein Expression Market?

The base year of this report is 2016.

Who are the major players in this market?

Bioneer Corporation, Biotechrabbit GmbH, CellFree Sciences Co., Jena Bioscience GmbH are some of the major players in the global market.

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