Cell Free Protein Expression Market By Product Type (E.Coli Cell-Free Protein Expression System, Rabbit Reticulocytes Cell-Free Protein Expression System, Wheat Germ Cell-Free Protein Expression System, Insect Cells Cell-Free Protein Expression System & Others), By Application Type (Enzyme Engineering, Protein Labeling, Protein-Protein Interaction & Others), By Expression Mode Type(Continuous Flow Expression, Batch Expression) - Growth, Share, Opportunities & Competitive Analysis, 2017-2025

For decades, the cell-free protein expression method has been used for the analysis of proteins. The most commonly used lysates include wheat germ or reticulocyte lysates. There is a tremendous improvement in E. coli and wheat germ-derived cell-free systems. The increased commercialization interest of biotechnology and biopharmaceutical companies (Qiagen, Roche, Novagen, and Invitrogen) in these tools has resulted in the growth of the cell-free protein expression market. A surge in research and development activities, increased interest in genomics and proteomics, and demand for biologics are some of the key factors propelling the growth of the cell-free protein expression market. However, one hindrance to using cell-free systems is the low yield of target proteins.

The report titled "Cell-Free Protein Expression Market: Growth, Future Prospects, and Competitive Analysis, 2017–2025" offers strategic insights into the overall cell-free protein expression market, along with the market size and estimates for the duration of 2015–2025. The said research study covers an in-depth analysis of multiple market segments based on the type of product, application, expression mode, and different geographies. The product types studied for analyzing the overall global cell-free protein expression market are majorly segmented into E. coli cell-free protein expression systems, rabbit reticulocytes cell-free protein expression systems, wheat germ cell-free protein expression systems, insect cells cell-free protein expression systems, mammalian cell-free protein expression systems, and consumables. The global cell-free protein expression market is segmented by application type into polyurethane, polyurethane/polycarbonate, and silicone. It is also segmented by expression mode into continuous flow expression and batch expression.

Geographically, the global cell-free protein expression market is studied for the following regional markets:

  • North America
  • U.S.
  • Canada
  • Europe
  • U.K.
  • Germany
  • Rest of Europe
  • Asia-Pacific
  • China
  • Japan
  • Rest of Asia Pacific
  • Latin America
  • Mexico
  • Brazil
  • Rest of LATAM
  • Middle East and Africa
  • UAE
  • Saudi Arabia
  • South Africa
  • Rest of the Middle East and Africa

The market size and forecast for these regional and country-level markets are presented in this study for the period 2015–2025. Market growth rates for the forecast period 2017–2025 are also included in this report, considering 2016 as the base year.

Along with quantitative information, qualitative information sets and assessment tools are provided in this study for a better analysis of the overall market scenario and future prospects. Information such as market inclination insights and drivers, challenges, and opportunities assists the readers in understanding the ongoing trends in the global cell-free protein expression market. Tools such as key player market positioning and appealing investment propositions provide readers with insights into the global cell-free protein expression market's competitive scenario. This report concludes with a company profiles section that highlights major information about the key players engaged in the global cell-free protein expression market. In-depth competitive environment analysis and historical (2015) market size data are also provided in the report.

Based on the type of product, the global cell-free protein expression market is segmented as follows:

  • E. coli cell-free protein expression system
  • Cell-Free Protein Expression System for Rabbit Reticulocytes
  • Wheat Germ Cell-free Protein Expression System
  • Insect Cells Cell-free Protein Expression System
  • Mammalian cell-free protein expression system
  • Consumables
  • Labeling Tags
  • Vectors

coli lysate is the most simple and well-established cell-free protein expression system for the high-yield production of prokaryotic proteins. In eukaryotic systems, the most widely used is the rabbit reticulocyte lysate (RRL) cell-free protein expression system. It is more efficient and reduces the probability of error when compared with the E. coli system. White germ lysate is another eukaryotic expression system that is popularly used, yields higher output compared to other eukaryotic systems, and is used for large protein expression methods. Insect cell lysate is also used for large-size protein expression. Because they are the most preferred method for producing human proteins, mammalian cell-free protein expression methods are expected to be the fastest-growing segment of the cell protein expression market. The rising demand for biologics and proteomics research and its application in human drug discovery is the driving factor for the growth of the mammalian cell-free protein expression system market.

Based on the type of application, the global cell-free protein expression market is segmented as follows:

  • Enzyme Engineering
  • Protein Labeling
  • Protein-Protein interaction
  • Protein Purification

Currently, cell-free protein expression is one of the most lucrative markets, with a high adoption rate by the biopharmaceutical and biotechnological industries. It is being widely used in high-throughput functional proteomics and genomics. Protein-protein interaction segments occupy the largest share of the cell-free protein market. There is also significant growth observed in the research and development of protein production and the generation of protein libraries, which contribute to the fast growth of the protein-protein interaction segment.

Based on the type of expression mode, the global cell-free protein expression market is segmented as follows:

  • Expression of continuous flow
  • Batch Expression

Conventionally, batch expression was used for the synthesis of target proteins, as it is an easy-to-handle, fast, and reliable source for protein synthesis. A novel technique, the continuous flow expression system, is used for the synthesis of both prokaryotic and eukaryotic proteins. Continuous-Exchange Cell-Free (CECF) protein synthesis systems yield better protein when compared with batch reactions. Thus, continuous flow expression systems account for a large share of the cell-free protein expression market, and they are expected to grow in the forecast period.

For the purpose of this study, the global cell-free protein expression market is geographically categorized into:

  • North America (U.S., Canada)
  • Europe (UK, Germany, and the rest of Europe)
  • Asia Pacific (China, Japan, and the Rest of Asia)
  • Latin America (LATAM)
  • Middle East and Africa (MEA)

Cell-free protein expression has emerged as a potent new technology that is constantly improving and expanding. Due to advances in CFPE, it is possible to scale protein synthesis from a small scale to a manufacturing scale, which has inspired applications in genomics and structural biology, personalized medicine, and proteomic industrial applications. At present, North America dominates the global cell-free protein expression market, followed by the European market. Huge investments in research and development and rising demand for protein synthesis are the main drivers for the growth of the cell protein fusion market. North America and Europe together occupy more than half of the global cell-free protein expression market. Asia-Pacific is anticipated to be the fastest-growing cell-free protein expression market. Rising R&D activities increased funding from the government and biopharmaceutical and biotechnology companies, and increased demand for protein synthesis are driving growth in emerging markets such as China and India.

Frequently Asked Questions:

The market for Cell Free Protein Expression Market is expected to reach US$ 282.3 Mn By 2025.

The Cell Free Protein Expression Market is expected to see significant CAGR growth over the coming years, at 5.9%.

The report is forecasted from 2017-2025.

The base year of this report is 2016.

Bioneer Corporation, Biotechrabbit GmbH, CellFree Sciences Co., Jena Bioscience GmbH are some of the major players in the global market.

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Published Date:  Jul 2017
Category:  Biotechnology
Report ID:   58536
Report Format:   PDF
Pages:   120
Rating:    4.7 (70)
Delivery Time: 24 Hours to 48 Hours   
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