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N-Acetylcysteine Market by Product Type (Spray, Tablet, Tracheal Drip) by Application (Medicine, Nutritional Supplements, Others): Growth, Future Prospects, and Competitive Analysis, 2015 – 2027

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Market Insights:

N-Acetylcysteine is a supplement form of amino acid named cysteine. It facilitates the bonding of amino acids glycine and glutamine for the creation of an essential antioxidant glutathione inside the human body. N-Acetylcysteine has applications as medicines and nutritional supplements. The global market is going to reach at USD 2,200 million in 2027 from USD 1,032.6 million in 2020, expanding at a CAGR of 21.3% during the period 2021 to 2027.

Increasing Incidence Rate of Paracetamol Overdose

The increasing demand for N-Acetylcysteine for treating acetaminophen poisoning and the increasing usage of N-Acetylcysteine across the healthcare industry is projected to bolster the market. Demand for acetaminophen is growing at a rapid pace, and so as the cases of paracetamol overdosing. Countries like the U.K., Australia, and the U.S. are facing a higher growth rate of paracetamol overdosing as compared to the growth rate of paracetamol itself. For instance, the number of paracetamol poisoning cases has increased by over 40% during the past decade in U.K. and Australia. The major reason behind increasing paracetamol poisoning is the availability of paracetamol over the counter around the world. N-Acetylcysteine is crucial in maintaining or restoring the depleted glutathione in the liver to improve the non-toxic metabolism of paracetamol.

However, certain adverse effects are also associated with the intake of N-Acetylcysteine. First, when taken in IV formulations, N-Acetylcysteine causes rash, itchiness, and urticaria. In addition, nausea, vomiting, fever, etc., are some of the most commonly found side effects of N-Acetylcysteine when taken in the form of inhalation formulation. While, oral intake of N-Acetylcysteine shows side effects such as rash, nausea, vol=mitting, etc. Secondly, if taken immediately before or after alcohol consumption, N-Acetylcysteine causes serious liver damage.

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Impact of COVID 19

COVID 19 had a significant impact on the global N-Acetylcysteine industry. As the hospitals focused on treating COVID 19 patients, the treatments for other ailments were deferred. It affected the sales of N-Acetylcysteine initially. The COVID-19 restrictions affected the production of N-Acetylcysteine at the beginning on account of disruption in logistics. However, when the restrictions were lifted, production improved. N-Acetylcysteine was given to COVID 19 patients with severe pulmonary ailments. It helped in the recovery of the global N-Acetylcysteine market to a certain extent. The global N-Acetylcysteine market is anticipated to better the pre-COVID 19 levels in the coming years.

North America is the leading N-Acetylcysteine market globally.

North America reported the vast majority of N-Acetylcysteine consumption over the past few years and accounted for nearly 40% of total revenue generated in 2020. North America is reportedly having the largest share of the total number of paracetamol overdose incidences. Moreover, hypertoxicity caused owing to an overdose of paracetamol is also higher in North America and Europe as compared to the Asia Pacific. This, in turn, drives the demand for N-Acetylcysteine at a rapid pace in the region. The U.S. is witnessing consumption of an all-time high level of paracetamol consumption. More than sixty million United States citizens intake acetaminophen on a weekly basis, which ends up in ever-rising cases of overdosage. Paracetamol poisoning ultimately resulted in emergency visits in excess of 50 thousand, over 2,500 hospitalizations, and a mortality rate of over 500 per annum.

Europe is the second leading geography for the consumption of N-Acetylcysteine as of 2020. The mortality rate of paracetamol overdosing has remained above 200 per annum in the U.K. alone. The Asia Pacific is also witnessing a strong growth rate on account of strong demand from China, India, Australia, Japan, South Korea, etc. Therefore, the demand for N-Acetylcysteine in the Asia Pacific is expected to grow at a rapid pace over the forecast period. Lack of awareness among end-users regarding side effects of N-Acetylcysteine, easy availability over the counter, and low cost of paracetamol is one of the major reasons behind overdose.

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Pulmonary ailments lead the global N-Acetylcysteine Market.

The nasal spray is leading the market for N-Acetylcysteine on account of growing chronic obstructive pulmonary disease and asthma. WHO has reported that over 65 million people worldwide suffer from chronic obstructive pulmonary disease, while asthma-related patients are reported to be over 335 million. This, in turn, drives the demand for nasal spray form of N-Acetylcysteine. Additionally, N-Acetylcysteine is one of the major drugs used in COVDI 19 patients suffering from severe pulmonary ailments. Similarly, oral and intravenous formulations are also used to treat different medical conditions.

Medicine application to dominate the global demand for N-Acetylcysteine

The major applications of N-Acetylcysteine are medicine and nutritional supplements. However, treatment accounts for more than a 42.3% share of the overall revenue generated by the global N-Acetylcysteine industry. The presence of nearly 38 million HIV patients drives the demand for N-Acetylcysteine. Moreover, it is used for the treatment of fibrosis, pulmonary ailments, flu, psychiatric disorders, inflammations, acetaminophen poisoning, and other medical conditions.

1.Preface

1.1.Report Description
1.1.1.Purpose of the Report
1.1.2.Target Audience
1.1.3.USP and Key Offerings
1.2.Research Scope
1.3.Research Methodology
1.3.1.Phase I – Secondary Research
1.3.2.Phase II – Primary Research
1.3.3.Phase III – Expert Panel Review
1.3.4.Approach Adopted
1.3.4.1.Top-Down Approach
1.3.4.2.Bottom-Up Approach
1.3.5.Assumptions
1.4.Market Segmentation

2.Executive Summary

2.1.Market Snapshot: Global N-Acetylcysteine Market

3.Market Dynamics

3.1.Introduction
3.1.1. Global N-Acetylcysteine Market Value, 2015-2027, (US$ Bn)
3.2.Market Dynamics
3.2.1.Key Growth Trends
3.2.2.Major Industry Challenges
3.2.3.Key Growth Pockets
3.3.Attractive Investment Proposition, 2020
3.3.1.Product Type
3.3.2.Application
3.3.3.Geography

4.Market Positioning of Key Players, 2020

4.1.Company market share of key players, 2020
4.2.Top 6 Players
4.3.Top 3 Players
4.4.Major Strategies Adopted by Key Players

5.COVID 19 Impact Analysis

5.1.Global N-Acetylcysteine Market Pre Vs Post COVID 19, 2019 – 2027
5.2.Impact on Import & Export
5.3.Impact on Demand & Supply

6.North America

6.1.North America N-Acetylcysteine Market, by Country, 2015-2027 (US$ Bn)
6.1.1.U.S.
6.1.2.Canada
6.1.3.Mexico
6.2.North America N-Acetylcysteine Market, by Product Type, 2015-2027 (US$ Bn)
6.2.1.Overview
6.2.2.Spray
6.2.3.Tablets
6.2.4.Tracheal Drip
6.3.North America N-Acetylcysteine Market, By Application, 2015-2027 (US$ Bn)
6.3.1.Overview
6.3.2.Medicine
6.3.3.Nutritional Supplements
6.3.4.Others

7.Europe

7.1.Europe N-Acetylcysteine Market, by Country, 2015-2027 (US$ Bn)
7.1.1.UK
7.1.2.France
7.1.3.Germany
7.1.4.Italy
7.1.5.Russia
7.1.6.Spain
7.1.7.Belgium
7.1.8.Netherland
7.1.9.Austria
7.1.10.Sweden
7.1.11.Poland
7.1.12.Denmark
7.1.13.Switzerland
7.1.14.Rest of Europe
7.2.Europe N-Acetylcysteine Market, by Product Type, 2015-2027 (US$ Bn)
7.2.1.Overview
7.2.2.Spray
7.2.3.Tablets
7.2.4.Tracheal Drip
7.3.Europe N-Acetylcysteine Market, By Application, 2015-2027 (US$ Bn)
7.3.1.Overview
7.3.2.Medicine
7.3.3.Nutritional Supplements
7.3.4.Others

8.Asia Pacific

8.1.Asia Pacific N-Acetylcysteine Market, by Country, 2015-2027 (US$ Bn)
8.1.1.China
8.1.2.Japan
8.1.3.South Korea
8.1.4.India
8.1.5.Australia
8.1.6.New Zealand
8.1.7.Taiwan
8.1.8.Southeast Asia
8.1.9.Central Asia
8.1.10.Rest of Asia Pacific
8.2.Asia Pacific N-Acetylcysteine Market, by Product Type, 2015-2027 (US$ Bn)
8.2.1.Overview
8.2.2.Spray
8.2.3.Tablets
8.2.4.Tracheal Drip
8.3.Asia Pacific N-Acetylcysteine Market, By Application, 2015-2027 (US$ Bn)
8.3.1.Overview
8.3.2.Medicine
8.3.3.Nutritional Supplements
8.3.4.Others

9.Latin America

9.1.Latin America N-Acetylcysteine Market, by Country, 2015-2027 (US$ Bn)
9.1.1.Brazil
9.1.2.Argentina
9.1.3.Peru
9.1.4.Chile
9.1.5.Colombia
9.1.6.Rest of Latin America
9.2.Latin America N-Acetylcysteine Market, by Product, 2015-2027 (US$ Bn)
9.2.1.Overview
9.2.2.Spray
9.2.3.Tablets
9.2.4.Tracheal Drip
9.3.Latin America N-Acetylcysteine Market, By Application, 2015-2027 (US$ Bn)
9.3.1.Overview
9.3.2.Medicine
9.3.3.Nutritional Supplements
9.3.4.Others

10.Middle East

10.1.Middle East N-Acetylcysteine Market, by Country, 2015-2027 (US$ Bn)
10.1.1.UAE
10.1.2.KSA
10.1.3.Israel
10.1.4.Turkey
10.1.5.Iran
10.1.6.Rest of Middle East
10.2.Middle East N-Acetylcysteine Market, by Product Type, 2015-2027 (US$ Bn)
10.2.1.Overview
10.2.2.Spray
10.2.3.Tablets
10.2.4.Tracheal Drip
10.3.Middle East N-Acetylcysteine Market, By Application, 2015-2027 (US$ Bn)
10.3.1.Overview
10.3.2.Medicine
10.3.3.Nutritional Supplements
10.3.4.Others

11.Africa

11.1.Africa N-Acetylcysteine Market, by Country, 2015-2027 (US$ Bn)
11.1.1.South Africa
11.1.2.Egypt
11.1.3.Nigeria
11.1.4.Rest of Africa
11.2.Africa N-Acetylcysteine Market, by Product Type, 2015-2027 (US$ Bn)
11.2.1.Overview
11.2.2.Spray
11.2.3.Tablets
11.2.4.Tracheal Drip
11.3.Africa N-Acetylcysteine Market, By Application, 2015-2027 (US$ Bn)
11.3.1.Overview
11.3.2.Medicine
11.3.3.Nutritional Supplements
11.3.4.Others

12.Global

12.1.Global N-Acetylcysteine Market, by Product Type, 2015-2027 (US$ Bn)
12.1.1.Overview
12.1.2.Spray
12.1.3.Tablets
12.1.4.Tracheal Drip
12.2.Global N-Acetylcysteine Market, By Application, 2015-2027 (US$ Bn)
12.2.1.Overview
12.2.2.Medicine
12.2.3.Nutritional Supplements
12.2.4.Others

13.Company Profiles

13.1.Cheng Yi Pharmaceutical Co Ltd
13.2.Donboo Amino Acid Co Ltd
13.3.Manus Aktteva
13.4.Biopharma LLP
13.5.Moehs Group
13.6.Ningbo Zhenhai Haide Amino Acid
13.7.Nippon Rika Co Ltd
13.8.PharmaZell
13.9.Xinyi Hanling Biological Engineering Co Ltd
13.10.Wuxi Enovo Chemical Co ltd
13.11. Zambon Pharma

List of Figures

FIG. 1 Global N-Acetylcysteine Market: Research Methodology
FIG. 2 Market Size Estimation – Top Down & Bottom up Approach
FIG. 3 Global N-Acetylcysteine Market Segmentation
FIG. 4 Global N-Acetylcysteine Market, by Product, 2019 (US$ Bn)
FIG. 5 Global N-Acetylcysteine Market, by Application, 2019 (US$ Bn)
FIG. 6 Global N-Acetylcysteine Market, by Geography, 2019 (US$ Bn)
FIG. 7 Attractive Investment Proposition, by Geography, 2019
FIG. 8 Global Market Positioning of Key N-Acetylcysteine Market Manufacturers, 2019
FIG. 9 Global N-Acetylcysteine Market Value Contribution, By Product, 2019 & 2027 (Value %)
FIG. 10 Global N-Acetylcysteine Market, by Product 1, Value, 2015-2027 (US$ Bn)
FIG. 11 Global N-Acetylcysteine Market, by Product 2, Value, 2015-2027 (US$ Bn)
FIG. 12 Global N-Acetylcysteine Market, by Product 3, Value, 2015-2027 (US$ Bn)
FIG. 13 Global N-Acetylcysteine Market, by Others, Value, 2015-2027 (US$ Bn)
FIG. 14 Global N-Acetylcysteine Market Value Contribution, By Application, 2019 & 2027 (Value %)
FIG. 15 Global N-Acetylcysteine Market, by Application 1, Value, 2015-2027 (US$ Bn)
FIG. 16 Global N-Acetylcysteine Market, by Application 2, Value, 2015-2027 (US$ Bn)
FIG. 17 Global N-Acetylcysteine Market, by Application 3, Value, 2015-2027 (US$ Bn)
FIG. 18 Global N-Acetylcysteine Market, by Others, Value, 2015-2027 (US$ Bn)
FIG. 19 U.S. N-Acetylcysteine Market, 2015-2027 (US$ Bn)
FIG. 20 Rest of North America N-Acetylcysteine Market, 2015-2027 (US$ Bn)
FIG. 21 U.K. N-Acetylcysteine Market, 2015-2027 (US$ Bn)
FIG. 22 Germany N-Acetylcysteine Market, 2015-2027 (US$ Bn)
FIG. 23 France N-Acetylcysteine Market, 2015-2027 (US$ Bn)
FIG. 24 Rest of Europe N-Acetylcysteine Market, 2015-2027 (US$ Bn)
FIG. 25 Japan N-Acetylcysteine Market, 2015-2027 (US$ Bn)
FIG. 26 China N-Acetylcysteine Market, 2015-2027 (US$ Bn)
FIG. 27 India N-Acetylcysteine Market, 2015-2027 (US$ Bn)
FIG. 28 Rest of Asia Pacific N-Acetylcysteine Market, 2015-2027 (US$ Bn)
FIG. 29 Middle East & Africa N-Acetylcysteine Market, 2015-2027 (US$ Bn)
FIG. 30 Latin America N-Acetylcysteine Market, 2015-2027 (US$ Bn)

List of Tables

TABLE 1 Market Snapshot: Global N-Acetylcysteine Market
TABLE 2 Global N-Acetylcysteine Market, by Product Type, 2015-2027 (US$ Bn)
TABLE 3 Global N-Acetylcysteine Market, by Application, 2015-2027 (US$ Bn)
TABLE 4 Global N-Acetylcysteine Market, by Geography, 2015-2027 (US$ Bn)
TABLE 5 North America N-Acetylcysteine Market, by Product Type, 2015-2027 (US$ Bn)
TABLE 6 North America N-Acetylcysteine Market, by Application, 2015-2027 (US$ Bn)
TABLE 7 North America N-Acetylcysteine Market, by Country, 2015-2027 (US$ Bn)
TABLE 8 Europe N-Acetylcysteine Market, by Product Type, 2015-2027 (US$ Bn)
TABLE 9 Europe N-Acetylcysteine Market, by Application, 2015-2027 (US$ Bn)
TABLE 10 Europe N-Acetylcysteine Market, by Country/Region, 2015-2027 (US$ Bn)
TABLE 11 Asia Pacific N-Acetylcysteine Market, by Product Type, 2015-2027 (US$ Bn)
TABLE 12 Asia Pacific N-Acetylcysteine Market, by Application, 2015-2027 (US$ Bn)
TABLE 13 Asia Pacific N-Acetylcysteine Market, by Country/Region, 2015-2027 (US$ Bn)
TABLE 14 Latin America N-Acetylcysteine Market, by Product Type, 2015-2027 (US$ Bn)
TABLE 15 Latin America N-Acetylcysteine Market, by Application, 2015-2027 (US$ Bn)
TABLE 16 Latin America N-Acetylcysteine Market, by Country/Region, 2015-2027 (US$ Bn)
TABLE 17 Middle East N-Acetylcysteine Market, by Product Type, 2015-2027 (US$ Bn)
TABLE 18 Middle East N-Acetylcysteine Market, by Application, 2015-2027 (US$ Bn)
TABLE 19 Middle East N-Acetylcysteine Market, by Country/Region, 2015-2027 (US$ Bn)
TABLE 20 Africa N-Acetylcysteine Market, by Product Type, 2015-2027 (US$ Bn)
TABLE 21 Africa N-Acetylcysteine Market, by Application, 2015-2027 (US$ Bn)
TABLE 22 Africa N-Acetylcysteine Market, by Country/Region, 2015-2027 (US$ Bn)
TABLE 23 Company 01: Company Snapshot (Company Overview; Product Portfolio; Financial Information; Key Developments)
TABLE 24 Company 2: Company Snapshot (Company Overview; Product Portfolio; Financial Information; Key Developments)
TABLE 25 Company 3: Company Snapshot (Company Overview; Product Portfolio; Financial Information; Key Developments)
TABLE 26 Company 4.: Company Snapshot (Company Overview; Product Portfolio; Financial Information; Key Developments)
TABLE 27 Company 5: Company Snapshot (Company Overview; Product Portfolio; Financial Information; Key Developments)
TABLE 28 Company 6: Company Snapshot (Company Overview; Product Portfolio; Financial Information; Key Developments
TABLE 29 Company 7: Company Snapshot (Company Overview; Product Portfolio; Financial Information; Key Developments
TABLE 30 Company 8: Company Snapshot (Company Overview; Product Portfolio; Financial Information; Key Developments
TABLE 31 Company 9: Company Snapshot (Company Overview; Product Portfolio; Financial Information; Key Developments
TABLE 32 Company 10: Company Snapshot (Company Overview; Product Portfolio; Financial Information; Key Developments
TABLE 33 Company 11: Company Snapshot (Company Overview; Product Portfolio; Financial Information; Key Developments
TABLE 34 Company 12: Company Snapshot (Company Overview; Product Portfolio; Financial Information; Key Developments
TABLE 35 Company 13: Company Snapshot (Company Overview; Product Portfolio; Financial Information; Key Developments

Frequently asked questions 

What are the consequences of COVID 19 on global N-Acetylcysteine industry?

There was impact of COVID 19 on demand of N-Acetylcysteine, however, production was hampered which in turn resulted into supply shortage. Overall industry reported decline in market size by around 5 to 10%.

Who are the top five players in the global N-Acetylcysteine industry?

Cheng Yi Pharmaceutical Co Ltd, Donboo Amino Acid Co Ltd, Manus Aktteva Biopharma LLP, Moehs Group, etc. are some of the most prominent players in the world. Although North America dominate consumption, Asia Pacific is major production region for N-Acetylcysteine.

Does the report cover paracetamol poisoning incidence rate?

The report covers in detail information of paracetamol poisoning incidence rate, paracetamol consumption and mortality rate thereof.

Which is the fastest growing application market for global N-Acetylcysteine industry?

Medicinal use is dominating the consumption of N-Acetylcysteine around the world. It accounted in excess to 40% share of the total revenue generated by the N-Acetylcysteine industry in 2020.

Which is the leading regional market for global N-Acetylcysteine industry?

Driven by higher paracetamol poisoning rate, the North America is most dominating region for N-Acetylcysteine industry and its is closely followed by Europe.

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