Gamma Knife Market By Range (Less than 14 cm, More than 14 cm); By Indication (Brain Tumors, Arteriovenous Malformations, Trigeminal Neuralgia, Other Neurological Disorders); By End-use (Hospitals, Specialty Clinics, Research Institutions); By Region – Growth, Share, Opportunities & Competitive Analysis, 2024 – 2032
The gamma knife market size was valued at USD 458.22 million in 2024 and is anticipated to reach USD 686.38 million by 2032, at a CAGR of 5.2 % during the forecast period (2024-2032).
REPORT ATTRIBUTE
DETAILS
Historical Period
2020-2023
Base Year
2024
Forecast Period
2025-2032
Gamma Knife Market Size 2024
USD 458.22 Million
Gamma Knife Market, CAGR
5.2%
Gamma Knife Market Size 2032
USD 686.38 Million
Key drivers include growing prevalence of neurological conditions, rising geriatric population, and increasing preference for minimally invasive procedures. Gamma knife technology offers high precision, reduced recovery times, and fewer complications compared to conventional surgery, making it a preferred choice among patients and healthcare providers. Continuous technological innovations, such as integration with imaging and planning systems, further enhance accuracy and boost clinical outcomes.
Regionally, North America dominates the gamma knife market due to advanced healthcare infrastructure, strong presence of key manufacturers, and favorable reimbursement policies. Europe follows closely, supported by government funding for cancer and neurology treatment centers. Asia-Pacific is expected to witness the fastest growth, fueled by rising healthcare investments, expanding patient awareness, and increasing adoption of advanced medical devices in countries like China, Japan, and India. Emerging markets in Latin America and the Middle East & Africa also offer growth opportunities.
Market Insights:
The gamma knife market was valued at USD 458.22 million in 2024 and is projected to reach USD 686.38 million by 2032 at a CAGR of 5.2%.
Rising prevalence of brain tumors, arteriovenous malformations, and neurological disorders is driving steady demand for advanced radiosurgery.
Minimally invasive treatment preference strengthens adoption, with gamma knife technology offering precision, fewer side effects, and faster recovery.
Technological advancements in imaging and software integration enhance treatment accuracy, reduce session times, and boost clinician confidence.
High equipment costs and limited skilled professionals restrict adoption in developing regions, creating access disparities.
North America led with 42% share in 2024, supported by advanced infrastructure, reimbursement policies, and leading manufacturers.
Asia-Pacific, with 22% share, is the fastest-growing region due to healthcare investments, medical tourism, and expanding awareness.
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Rising Prevalence of Neurological Disorders and Tumors:
The growing burden of brain tumors, arteriovenous malformations, and functional neurological disorders has created consistent demand for advanced treatment methods. The gamma knife market benefits from its precision in targeting affected brain tissues without harming surrounding areas. Rising life expectancy and aging populations contribute to higher incidence rates, strengthening the need for such solutions. It offers an effective alternative for patients unsuitable for open surgery.
For instance, Elekta’s Leksell Gamma Knife Esprit system, cleared by the FDA in October 2022, enhances treatment precision by enabling targeting of even the smallest and most challenging intracranial tumors while sparing healthy tissue, with over 50 years of clinical evidence supporting its use.
Healthcare systems and patients increasingly prefer minimally invasive therapies that reduce risks and recovery times. The gamma knife market responds to this demand by offering accurate, non-invasive radiosurgery. It delivers focused radiation with fewer side effects compared to conventional procedures. Hospitals and specialty centers adopt the technology to enhance patient outcomes and lower overall treatment costs.
For instance, Elekta’s Leksell Gamma Knife® Icon achieves targeting precision of 0.25 millimeter, ensuring highly accurate dose delivery while sparing surrounding healthy tissue.
Continuous Technological Advancements in Radiosurgery Systems:
Ongoing innovation in imaging, software, and planning tools has improved the efficiency of gamma knife systems. The gamma knife market benefits from enhanced accuracy, shorter treatment sessions, and integration with advanced imaging modalities. These improvements raise clinician confidence and encourage broader adoption across neurological care facilities. It provides precise treatment options that align with evolving standards in medical technology.
Growing Healthcare Investments and Expanding Access to Advanced Care:
Governments and private providers continue to increase funding for advanced neurological care. The gamma knife market gains from rising hospital infrastructure projects and favorable reimbursement frameworks. Developing economies invest in high-end medical devices to meet patient needs and attract medical tourism. It strengthens its role as a critical solution for addressing complex neurological conditions worldwide.
Market Trends:
Integration of Imaging and Artificial Intelligence in Radiosurgery:
Technological progress is shaping the gamma knife market with the integration of advanced imaging and artificial intelligence. Modern systems now combine MRI, CT, and PET scans to improve targeting accuracy during procedures. AI-driven planning tools support clinicians in mapping treatment zones with higher precision and speed. It reduces human error and enhances patient safety, while also improving workflow efficiency in hospitals. The growing focus on precision medicine aligns with these innovations, creating stronger demand for smarter radiosurgery systems. Leading manufacturers invest heavily in R&D to bring integrated platforms to market. This trend strengthens the clinical value proposition of gamma knife technology across global healthcare facilities.
For instance, Brainlab’s Elements SmartBrush Spine module generated clinical target volumes for 21 spine SBRT cases with a mean Dice similarity coefficient of 0.86, matching expert contours with only 1.9 mm average center-of-mass deviation.
Expansion of Accessibility Through Healthcare Infrastructure and Medical Tourism:
Growing investment in hospital infrastructure is expanding access to advanced radiosurgery systems. The gamma knife market is witnessing broader adoption across emerging economies where governments and private institutions prioritize cancer and neurological treatment centers. Medical tourism has further accelerated demand, with patients traveling to regions offering cost-effective yet advanced care. It provides healthcare providers with an opportunity to strengthen their service portfolio and attract international patients. Strategic partnerships between hospitals and technology providers are driving system installations in key growth markets. Rising awareness campaigns are also helping patients understand the benefits of non-invasive treatments. This expansion trend underscores the shift toward global accessibility of precision radiosurgery.
For Instance, American Shared Hospital Services (ASHS) entered a joint venture with Hospital San Javier in Guadalajara, Mexico, to upgrade its existing Gamma Knife system to the Elekta Esprit model, expanding advanced radiosurgery access for patients in Mexico, which has a population of over 130 million.
Market Challenges Analysis:
High Cost of Equipment and Limited Availability in Developing Regions:
One of the major challenges for the gamma knife market is the high cost of acquisition and installation. Hospitals and clinics face significant financial barriers when investing in advanced radiosurgery systems. It restricts adoption in developing regions where healthcare budgets remain constrained. Limited availability of skilled professionals also adds to the challenge, as specialized training is required to operate these systems effectively. The high initial investment often discourages smaller hospitals from adopting the technology. This creates unequal access, leaving advanced treatment concentrated in urban centers and specialized institutions.
Reimbursement Complexities and Competition from Alternative Treatments:
Complex reimbursement policies often hinder the broader adoption of gamma knife procedures. The gamma knife market faces challenges in securing consistent coverage across healthcare systems, making affordability a concern for patients. It also faces competition from other radiosurgery and surgical options that may be more accessible or cost-effective. Some healthcare providers prioritize linear accelerators and proton therapy due to their broader application scope. Patient hesitation and limited awareness of the technology further slow growth. These challenges highlight the need for policy reforms and stronger awareness campaigns to ensure wider acceptance.
Market Opportunities:
Rising Demand for Non-Invasive Neurological Treatments Globally:
Growing awareness of non-invasive treatments presents strong opportunities for the gamma knife market. Patients increasingly seek alternatives that offer reduced hospital stays, minimal side effects, and quicker recovery. It positions gamma knife radiosurgery as a preferred option for treating brain tumors and vascular disorders. Expanding geriatric populations worldwide also create a larger patient base for advanced neurological care. Healthcare providers are likely to invest in these systems to strengthen their service portfolios. Favorable clinical outcomes further drive adoption, supporting stronger demand across developed and emerging markets.
Expansion into Emerging Economies and Medical Tourism Growth:
Emerging economies represent significant opportunities with rising healthcare spending and infrastructure development. The gamma knife market can grow through system installations in Asia-Pacific, Latin America, and the Middle East, where patient volumes are increasing. It aligns with governments’ focus on modernizing healthcare and addressing cancer care gaps. Medical tourism adds momentum as patients travel for cost-effective yet advanced treatment. Partnerships between manufacturers and regional healthcare providers are expected to accelerate market penetration. Strategic collaborations and funding initiatives will enhance accessibility, creating long-term opportunities for growth.
Market Segmentation Analysis:
By Range:
The gamma knife market is segmented by range into less than 14 cm and more than 14 cm treatment capacities. Systems with more than 14 cm range hold strong demand due to their ability to address larger and more complex brain tumors. It offers flexibility for diverse patient needs and expands clinical applications. Smaller range systems remain relevant for precision-focused treatments in cases requiring high accuracy with minimal invasiveness. Hospitals often prioritize higher range models to broaden treatment capabilities.
For instance, the Leksell Gamma Knife Icon version delivers sub-millimeter accuracy with mask-based immobilization and highly precise 4 mm and 8 mm collimator sizes designed for treating small brain lesions with a total geometric accuracy of less than ±0.5 mm.
By Indication:
The gamma knife market addresses a variety of indications including brain tumors, arteriovenous malformations, trigeminal neuralgia, and other neurological disorders. Brain tumors account for the largest segment due to rising incidence and preference for non-invasive treatment. It is also highly effective in functional disorders where traditional surgery poses higher risks. Expanding applications across neurological conditions continue to boost adoption. Growing awareness of gamma knife benefits supports sustained demand in this segment.
For Instance, Mayo Clinic has performed Gamma Knife radiosurgery on over 10,000 patients with brain tumors, achieving tumor control rates often exceeding 90%.
By End-use:
End-use segmentation highlights adoption across hospitals, specialty clinics, and research institutions. Hospitals dominate the gamma knife market owing to strong infrastructure, availability of advanced imaging tools, and skilled professionals. Specialty clinics show steady growth with increasing demand for focused outpatient care. It reflects the trend toward decentralizing advanced neurosurgical procedures beyond large hospitals. Research institutions also contribute by testing innovations and expanding treatment applications. This diverse adoption strengthens the long-term growth of the market.
Segmentations:
By Range
Less than 14 cm
More than 14 cm
By Indication
Brain Tumors
Arteriovenous Malformations
Trigeminal Neuralgia
Other Neurological Disorders
By End-use
Hospitals
Specialty Clinics
Research Institutions
By Region
North America
U.S.
Canada
Mexico
Europe
UK
France
Germany
Italy
Spain
Russia
Belgium
Netherlands
Austria
Sweden
Poland
Denmark
Switzerland
Rest of Europe
Asia Pacific
China
Japan
South Korea
India
Australia
Thailand
Indonesia
Vietnam
Malaysia
Philippines
Taiwan
Rest of Asia Pacific
Latin America
Brazil
Argentina
Peru
Chile
Colombia
Rest of Latin America
Middle East
UAE
KSA
Israel
Turkey
Iran
Rest of Middle East
Africa
Egypt
Nigeria
Algeria
Morocco
Rest of Africa
Regional Analysis:
North America:
North America accounted for 42% market share in 2024, maintaining its lead in the gamma knife market. The region benefits from advanced healthcare infrastructure, high treatment adoption rates, and favorable reimbursement policies. It also supports growth with significant investments in neurology and oncology centers. The presence of leading manufacturers and research collaborations further drive innovation and adoption. High awareness among patients and clinicians supports steady demand. The U.S. dominates within the region due to widespread installations and early adoption of advanced radiosurgery systems.
Europe:
Europe captured 28% market share in 2024, ranking as the second-largest regional market. Strong government support for cancer care and neurological treatments fuels growth across major countries. It benefits from established hospital networks and widespread clinical research in radiosurgery. Favorable healthcare policies encourage investments in advanced treatment systems. Germany, France, and the U.K. lead installations, supported by public funding and patient demand. Rising incidence of brain disorders drives continuous system adoption across specialized centers. Europe maintains a strong foundation for sustained growth in the coming years.
Asia-Pacific :
Asia-Pacific held 22% market share in 2024, marking it as the fastest-growing regional segment. Rising healthcare investments and expanding infrastructure in China, Japan, and India fuel demand in the gamma knife market. It gains traction with growing patient awareness and government initiatives to modernize cancer care. Medical tourism contributes to regional growth, offering cost-effective treatment options with advanced systems. Strategic partnerships between global manufacturers and regional hospitals strengthen accessibility. Expanding patient bases and supportive funding mechanisms create a robust growth outlook. Asia-Pacific continues to position itself as a key driver of global market expansion.
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MASEP Medical Science & Technology Development Co. (China)
CQ Medical (U.S.)
Panacea Medical Technologies Pvt. Ltd. (India)
Akesis, Inc. (U.S.)
Fortis Healthcare (India)
ONO SOKKI CO., LTD (India)
Corewell Health (U.S.)
Competitive Analysis:
The gamma knife market is highly competitive with strong participation from global and regional players. Key companies include Elekta (Sweden), Accuray Incorporated (U.S.), Vision RT Ltd. (U.K.), Varian (U.S.), Nordion Inc. (Canada), Brainlab AG (Germany), MASEP Medical Science & Technology Development Co. (China), CQ Medical (U.S.), Panacea Medical Technologies Pvt. Ltd. (India), and Akesis, Inc. (U.S.). These companies compete through innovation, technological integration, and strategic collaborations with healthcare providers. It is driven by continuous research and development to improve accuracy, reduce treatment times, and enhance patient outcomes. Leading players also focus on expanding their presence in emerging markets through partnerships and system installations. Competitive intensity is strengthened by investments in software advancements, artificial intelligence, and advanced imaging integration. This dynamic landscape fosters innovation while pushing companies to differentiate through product performance, service quality, and cost efficiency.
Recent Developments:
In July 2024, Vision RT announced a long-term strategic partnership with DoseOptics LLC to develop DoseRT™ powered by BeamSite®, integrating Cherenkov imaging with surface guided radiation therapy for better treatment visualization.
In February 2025, Nordion entered into a partnership with Sterigenics International to establish a reliable, long-term supply of medical isotopes. Additionally, Ontario Power Generation’s Darlington Nuclear Unit 1 resumed production of Cobalt-60 critical for Nordion’s supply chain.
Report Coverage:
The research report offers an in-depth analysis based on Range, Indication, End-use and Region. It details leading Market players, providing an overview of their business, product offerings, investments, revenue streams, and key applications. Additionally, the report includes insights into the competitive environment, SWOT analysis, current Market trends, as well as the primary drivers and constraints. Furthermore, it discusses various factors that have driven Market expansion in recent years. The report also explores Market dynamics, regulatory scenarios, and technological advancements that are shaping the industry. It assesses the impact of external factors and global economic changes on Market growth. Lastly, it provides strategic recommendations for new entrants and established companies to navigate the complexities of the Market.
Future Outlook:
The gamma knife market will expand with rising demand for non-invasive treatment of neurological disorders.
Technological integration with artificial intelligence and imaging systems will enhance treatment accuracy and efficiency.
Hospitals and specialty centers will increase adoption to meet patient demand for advanced radiosurgery.
Growing healthcare investments in developing economies will create new opportunities for system installations.
The aging global population will continue to drive a higher incidence of brain-related conditions requiring treatment.
Medical tourism will strengthen the role of cost-effective advanced treatments in emerging regions.
Manufacturers will focus on R&D to improve device portability, precision, and ease of use.
Reimbursement reforms and supportive healthcare policies will encourage wider adoption of advanced procedures.
Awareness campaigns will educate patients on the benefits of non-invasive neurosurgical solutions.
Collaborations between technology providers and hospitals will drive accessibility and strengthen long-term market growth.
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Frequently Asked Questions
What is the current market size for the gamma knife market, and what is its projected size in 2032?
The gamma knife market was valued at USD 458.22 million in 2024 and is projected to reach USD 686.38 million by 2032. This growth reflects increasing adoption of advanced radiosurgery systems across global healthcare facilities.
At what Compound Annual Growth Rate is the gamma knife market projected to grow between 2024 and 2032?
The gamma knife market is projected to grow at a CAGR of 5.2% during the forecast period of 2024–2032. It reflects steady demand driven by rising neurological cases and adoption of non-invasive treatments.
Which gamma knife market segment held the largest share in 2024?
By indication, the brain tumor segment held the largest share in 2024. Hospitals also accounted for the leading share in the end-use category.
What are the primary factors fueling the growth of the gamma knife market?
Key drivers include rising prevalence of neurological disorders, growing geriatric population, and increasing demand for minimally invasive procedures. Technological advancements in imaging and treatment planning also fuel growth.
Who are the leading companies in the gamma knife market?
Leading players include Elekta, Accuray Incorporated, Vision RT Ltd., Varian, Nordion Inc., Brainlab AG, MASEP Medical, CQ Medical, Panacea Medical Technologies, and Akesis, Inc. These companies focus on innovation and global expansion.
Which region commanded the largest share of the gamma knife market in 2024?
North America commanded the largest share with 42% in 2024. Strong healthcare infrastructure, favorable reimbursement policies, and advanced technology adoption drive its leadership.
About Author
Shweta Bisht
Healthcare & Biotech Analyst
Shweta is a healthcare and biotech researcher with strong analytical skills in chemical and agri domains.
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