Topical Excipients Market

Market Insights

According to the World Health Organization’s 2015 report, noncommunicable diseases account for 70% of chronic disease deaths, with communicable diseases accounting for the remaining 30%. Pharmaceutical industries are investing a huge amount of revenue in the formulation and development studies needed to deliver drugs effectively to the human body. Excipients are subjected to intense scrutiny and modification in order to achieve desired physical and chemical characterization of drug formulations.

In the product segment for topical excipients, inorganic chemicals, and organic chemicals are studied. The inorganic chemicals consist of calcium phosphate, calcium carbonate, calcium sulfate, magnesium stearate, metallic oxides, and others. Organic chemicals are segmented as starch, cellulose, petrochemicals, oleochemicals, and other organic chemicals. Starch is further sub-segmented as modified starch, dried starch, and converted starch. Cellulose includes cellulose ethers, microcrystalline cellulose, cellulose esters, CMC, and croscarmellose sodium. Petrochemicals considered topical excipients are glycols, povidones, mineral hydrocarbons, acrylic polymers, and other petrochemical excipients. Glycols consist of polyethylene glycol and propylene glycol.

Mineral hydrocarbons majorly comprise petrolatum, mineral waxes, and mineral oils. Oleochemicals are further categorized as fatty acids, mineral stearate, glycerin, and other oleochemical excipients. The excipients find different functions in drug formulation, such as buffers, adsorbents, permeation enhancers, surfactants, stabilizers, emulsifiers, preservatives, chelating agents, polymers, humectants, and others. Market estimation and data mining are performed for the product and function segments, respectively.

Cross-country sectional analysis is performed to understand the market trend of topical excipients at the regional level.

There is tremendous diversity in the topical excipients that are used in drug formulation, and hence it is very important to understand the competition existing in the topical excipients market. A market assessment gives a brief idea regarding the latest trend in the preference of excipients for drug formulation. Company profiles will furnish the entire product range of the excipients and financial information about the companies. Manufacturers influencing the topical excipients market are Ashland, Inc., AkzoNobel, Roquette Group, BASF SE, J. M. Huber Corporation, The Dow Chemical Company, The Lubrizol Corporation, FMC Corporation, Evonik Industries AG, Merck Millipore, Associated British Foods Plc, Croda International Plc, Archer Daniels Midland Company, and others.

Based on product, the global topical excipients market is categorized into:

Inorganic Chemicals

• • Calcium Phosphate
  • Calcium Carbonate
  • Calcium Sulfate
  • Magnesium Stearate
  • Metallic Oxides
  • Others

Organic Chemicals

Starch

• Modified Starch
• Dried Starch
• Converted Starch

Cellulose

• Cellulose Ethers
• Microcrystalline Cellulose
• Cellulose Esters
• CMC and croscarmellose sodium
• Petrochemicals

Glycols

• Polyethylene Glycols
• Propylene Glycols
• Povidones

Mineral Hydrocarbons

• Petrolatum
• Mineral Waxes
• Mineral Oils
• Acrylic Polymers
• Other petrochemical excipients

Oleochemicals

• Fatty Acids
• Mineral Stearate
• Glycerin
• Other Oleochemical Excipients
• Other Organic Chemicals (Aloe Vera, Vitamin E Oil, and Others)

Excipients are very important during the formulation of active pharmaceutical ingredients. It has an important role in delivering the drug into the human body. It has no medicinal properties but streamlines the production of drug molecules and promotes the physical absorption of drugs. They are useful in enhancing the physical properties of drug formulation, such as disintegration time, lubricant, flowability, taste masking, etc. Organic chemicals are the most frequently used excipients in drug formulation owing to their enhanced compatibility with active pharmaceutical ingredients. Organic chemicals have undergone technical modification during the novel drug delivery studies, thereby improving the flowability, drug absorption capacity, and disintegration time of the drug formulation. Inorganic chemicals, due to their inert nature, are mostly used as fillers and taste masking agents in drug formulation.

Manufacturers influencing the topical excipients market are Ashland, Inc., AkzoNobel, Roquette Group, BASF SE, J. M. Huber Corporation, The Dow Chemical Company, The Lubrizol Corporation, FMC Corporation, Evonik Industries AG, Merck Millipore, Associated British Foods Plc, Croda International Plc, Archer Daniels Midland Company, and others.

Based on function, the topical excipients market is categorized into:

• Buffers
• Adsorbents
• Permeation Enhancers
• Surfactants
• Stabilizers
• Emulsifiers
• Preservatives
• Chelating Agents
• Polymers
• Humectants
• Others (co-solvents, preservatives, thickening agents, and smoothing agents)

On the basis of the functional properties of excipients, they are utilized for making solid, semisolid, and liquid drug formulations. Stabilizers and emulsifiers are mostly used in semisolid and liquid dosage forms. Stabilizers such as benzophenone and butylated hydroxytoluene derivatives are chemical moieties that prevent chemical, oxidative, and light-sensitive degradation of active pharmaceutical ingredients. Emulsifiers such as lecithin and taurocholic acid enhance the miscibility of oil-liquid and liquid-gas phases to promote product shelf life and attain smooth drug delivery.

Preservatives and buffers are mandatory excipients in a drug formulation as they preserve and protect the drug formulation from microbial contamination and drug deterioration due to changes in pH, which, if unchecked, would result in serious adverse effects. Surfactants are the subject of extensive research, with cationic surfactants being developed in various micelle concentrations to improve drug delivery.

For the purpose of this study, the global topical excipients market is categorized into the following regional and country-specific markets:

• North America
  • U.S.
  • Canada
• Europe
  • Germany
  • France
  • Italy
  • U.K.
  • Russia
  • Rest of Europe
• Asia-Pacific
  • India
  • China
  • Japan
  • Rest of Asia-Pacific
• Latin America
  • Brazil
  • Mexico
  • Rest of Latin America
• Middle East and Africa
  • GCC Countries
  • South Africa
  • Rest of Middle East and Africa

The Centers for Disease Control and Prevention state that in the United States, 7 in 10 people suffer from health complications and immediately require medical intervention. The rising prevalence of health complications and the domicile of market leaders manufacturing topical excipients buttress the growth of topical excipients in North America. Western Europe is a leader in the production of high-quality topical excipients, with pharmaceutical companies investing heavily in drug formulation accelerated stability testing studies. Asia Pacific is an attractive market destination for topical excipients on account of its large ailing population, huge production of generic drug formulation, and the establishment of major pharmaceutical players engaged in the production of branded drugs, which supports the Asian Pacific market’s growth.

Chapter 1. Preface
1.1. Report Scope and Description
1.2. Research Methodology
1.2.1. Phase I-Secondary Research
1.2.2. Phase II-Primary Research
1.2.3. Phase III-Expert Panel Review
1.2.4. Assumptions
1.2.5. Approach Adopted

Chapter 2. Executive Summary
2.1. Global Topical Excipients Market Portraiture
2.1.1. Global Topical Excipients Market, by Product, 2016 (Value %)
2.1.2. Global Topical Excipients Market, by Function, 2016 (Value %)
2.1.3. Global Topical Excipients Market, by Geography, 2016 (Value %)

Chapter 3. Topical Excipients Market: Dynamics and Future Outlook
3.1. Market Overview
3.2. Drivers
3.3. Challenges
3.4. Opportunities
3.5. Attractive Investment Proposition, by Geography
3.6. Top 3 Countries: Global Topical Excipients Market, 2015-2025 (US$ Mn)
3.7. Competitive Landscape : Global Topical Excipients Market, by Key Players, 2015-2025 (US$ Mn)

Chapter 4. Global Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
4.1. Overview
4.1.1. Competitive Analysis: Global Topical Excipients Market, by Product, 2016 Vs. 2025 (Value %)
4.2. Inorganic Chemicals
4.2.1. Calcium Phosphate
4.2.2. Calcium Carbonate
4.2.3. Calcium Sulfate
4.2.4. Magnesium Stearate
4.2.5. Metallic Oxides
4.2.6. Others
4.3. Organic Chemicals
4.3.1. Starch
4.3.1.1. Modified Starch
4.3.1.2. Dried Starch
4.3.1.3. Converted Starch
4.3.2. Cellulose
4.3.2.1. Cellulose Ethers
4.3.2.2. Microcrystalline Cellulose
4.3.2.3. Cellulose Esters
4.3.2.4. CMC and Croscarmellose Sodium
4.3.3. Petrochemicals
4.3.3.1. Glycols
4.3.3.1.1. Polyethylene Glycols
4.3.3.1.2. Propylene Glycols
4.3.3.2. Povidones
4.3.3.3. Mineral Hydrocarbons
4.3.3.3.1. Petrolatum
4.3.3.3.2. Mineral Waxes
4.3.3.3.3. Mineral Oils
4.3.3.4. Acrylic Polymers
4.3.3.5. Other Petrochemical Excipients
4.3.4. Oleochemicals
4.3.4.1. Fatty Acids
4.3.4.2. Mineral Stearate
4.3.4.3. Glycerin
4.3.4.4. Other Oleochemicals Excipients
4.3.5. Other Organic Chemicals (Aloe vera, Vitamin E Oil and Others)

Chapter 5. Global Topical Excipients Market, by Function, 2015 – 2025 (US$ Mn)
5.1. Overview
5.1.1. Competitive Analysis: Global Topical Excipients Market, by Function, 2016 Vs. 2025 (Value %)
5.2. Buffers
5.3. Adsorbents
5.4. Permeation Enhancers
5.5. Surfactants
5.6. Stabilizers
5.7. Emulsifiers
5.8. Preservatives
5.9. Chelating Agents
5.10. Polymers
5.11. Humectants
5.12. Others (Co-Solvents, Preservatives, Thickening Agent and Smoothening Agents)

Chapter 6. Global Topical Excipients Market, by Geography, 2015 – 2025 (US$ Mn)
6.1. Overview
6.2. North America Topical Excipients Market Analysis, 2015 – 2025
6.2.1. North America Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
6.2.2. North America Topical Excipients Market, by Function, 2015 – 2025 (US$ Mn)
6.2.3. North America Topical Excipients Market, by Country, 2015 – 2025 (US$ Mn)
6.2.3.1. U.S.
6.2.3.2. Canada
6.3. Europe Topical Excipients Market Analysis, 2015 – 2025
6.3.1. Europe Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
6.3.2. Europe Topical Excipients Market, by Function, 2015 – 2025 (US$ Mn)
6.3.3. Europe Topical Excipients Market, by Country, 2015 – 2025 (US$ Mn)
6.3.3.1. U.K.
6.3.3.2. Germany
6.3.3.3. Rest of Europe
6.4. Asia Pacific Topical Excipients Market Analysis, 2015 – 2025
6.4.1. Asia Pacific Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
6.4.2. Asia Pacific Topical Excipients Market, by Function, 2015 – 2025 (US$ Mn)
6.4.3. Asia Pacific Topical Excipients Market, by Country, 2015 – 2025 (US$ Mn)
6.4.3.1. Japan
6.4.3.2. China
6.4.3.3. India
6.4.3.4. Rest of Asia Pacific
6.5. Latin America Topical Excipients Market Analysis, 2015 – 2025
6.5.1. Latin America Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
6.5.2. Latin America Topical Excipients Market, by Function, 2015 – 2025 (US$ Mn)
6.5.3. Latin America Topical Excipients Market, by Country, 2015 – 2025 (US$ Mn)
6.5.3.1. Brazil
6.5.3.2. Mexico
6.5.3.3. Rest of Latin America
6.6. Middle East & Africa Topical Excipients Market Analysis, 2015 – 2025
6.6.1. Middle East and Africa Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
6.6.2. Middle East and Africa Topical Excipients Market, by Function, 2015 – 2025 (US$ Mn)
6.6.3. Middle East and Africa Topical Excipients Market, by Region, 2015 – 2025 (US$ Mn)
6.6.3.1. GCC
6.6.3.2. Rest of Middle East and Africa

Chapter 7. Company Profiles
7.1. Ashland, Inc.
7.1.1. Business Description
7.1.2. Financial Information (Subject to data availability)
7.1.3. Product Portfolio
7.1.4. Key Developments
7.2. AkzoNobel
7.3. Associated British Foods Plc
7.4. Archer Daniels Midland Company
7.5. BASF SE
7.6. Croda International Plc
7.7. Evonik Industries AG
7.8. FMC Corporation
7.9. J.M.Huber Corporation
7.10. Merck Millipore
7.11. Roquette Group
7.12. The DOW Chemical Company
7.13. The Lubrizol Corporation

List of Figures

FIG. 1 Topical Excipients: Market Segmentation
FIG. 2 Global Topical Excipients Market Share, by Product, 2016 (Value %)
FIG. 3 Global Topical Excipients Market Share, by Function, 2016 (Value %)
FIG. 4 Global Topical Excipients Market Share, by Geography, 2016 (Value %)
FIG. 5 Attractive Investment Proposition, by Geography
FIG. 6 Market Competition Landscape, by Key Players, 2016
FIG. 7 Competitive Analysis, Global Topical Excipients Market, by Product, 2016 Vs. 2025 (Value %)
FIG. 8 Global Calcium Phosphate Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 9 Global Calcium Carbonate Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 10 Global Calcium Sulfate Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 11 Global Magnesium Stearate Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 12 Global Metallic Oxides Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 13 Global Other Inorganic Chemicals Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 14 Global Modified Starch Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 15 Global Dried Starch Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 16 Global Converted Starch Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 17 Global Cellulose Ethers Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 18 Global Microcrystalline Cellulose Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 19 Global Cellulose Esters Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 20 Global CMC and Croscarmellose Sodium Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 21 Global Polyethylene Glycols Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 22 Global Propylene Glycols Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 23 Global Povidone Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 24 Global Petrolatum Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 25 Global Mineral Waxes Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 26 Global Mineral Oils Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 27 Global Acrylic Polymers Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 28 Global Other Petrochemical Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 29 Global Fatty Acids Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 30 Global Mineral Stearate Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 31 Global Glycerine Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 32 Global Other Oleochemicals Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 33 Global Other Organic Chemicals Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 34 Competitive Analysis, Global Topical Excipients Market, by Function, 2016 Vs. 2025 (Value %)
FIG. 35 Global Buffers Market for Topical Excipients, 2015 – 2025 (US$ Mn)
FIG. 36 Global Adsorbents Market for Topical Excipients, 2015 – 2025 (US$ Mn)
FIG. 37 Global Permeation Enhancers Market for Topical Excipients, 2015 – 2025 (US$ Mn)
FIG. 38 Global Surfactant Market for Topical Excipients, 2015 – 2025 (US$ Mn)
FIG. 39 Global Stabilizers Market for Topical Excipients, 2015 – 2025 (US$ Mn)
FIG. 40 Global Emulsifiers Market for Topical Excipients, 2015 – 2025 (US$ Mn)
FIG. 41 Global Preservatives Market for Topical Excipients, 2015 – 2025 (US$ Mn)
FIG. 42 Global Chelating Agents Market for Topical Excipients, 2015 – 2025 (US$ Mn)
FIG. 43 Global Polymer Market for Topical Excipients, 2015 – 2025 (US$ Mn)
FIG. 44 Global Humectants Market for Topical Excipients, 2015 – 2025 (US$ Mn)
FIG. 45 Global Other Functions Market for Topical Excipients, 2015 – 2025 (US$ Mn)
FIG. 46 U.S. Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 47 Canada Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 48 U.K. Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 49 Germany Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 50 Rest of Europe Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 51 Japan Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 52 China Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 53 India Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 54 Rest of Asia Pacific Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 55 Brazil Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 56 Mexico Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 57 Rest of Latin America Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 58 GCC Topical Excipients Market, 2015 – 2025 (US$ Mn)
FIG. 59 Rest of Middle East and Africa Topical Excipients Market, 2015 – 2025 (US$ Mn)

List of Tables

TABLE 1 Global Topical Excipients Market Portraiture
TABLE 2 Global Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
TABLE 3 Global Inorganic Chemicals Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
TABLE 4 Global Organic Chemicals Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
TABLE 5 Global Starch Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
TABLE 6 Global Cellulose Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
TABLE 7 Global Petrochemicals Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
TABLE 8 Global Glycols Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
TABLE 9 Global Mineral Hydrocarbons Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
TABLE 10 Global Oleochemicals Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
TABLE 11 Global Topical Excipients Market, by Function, 2015 – 2025 (US$ Mn)
TABLE 12 Global Topical Excipients Market, by Geography, 2015 – 2025 (US$ Mn)
TABLE 13 North America Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
TABLE 14 North America Topical Excipients Market, by Function, 2015 – 2025 (US$ Mn)
TABLE 15 North America Topical Excipients Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 16 Europe Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
TABLE 17 Europe Topical Excipients Market, by Function, 2015 – 2025 (US$ Mn)
TABLE 18 Europe Topical Excipients Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 19 Asia Pacific Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
TABLE 20 Asia Pacific Topical Excipients Market, by Function, 2015 – 2025 (US$ Mn)
TABLE 21 Asia Pacific Topical Excipients Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 22 Latin America Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
TABLE 23 Latin America Topical Excipients Market, by Function, 2015 – 2025 (US$ Mn)
TABLE 24 Latin America Topical Excipients Market, by Country, 2015 – 2025 (US$ Mn)
TABLE 25 Middle East and Africa Topical Excipients Market, by Product, 2015 – 2025 (US$ Mn)
TABLE 26 Middle East and Africa Topical Excipients Market, by Function, 2015 – 2025 (US$ Mn)
TABLE 27 Middle East and Africa Topical Excipients Market, by Region, 2015 – 2025 (US$ Mn)
TABLE 28 Ashland, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 29 AkzoNobel: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 30 Associated British Foods Plc: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 31 Archer Daniels Midland Company: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 32 BASF SE: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 33 Croda International Plc: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 34 Evonik Industries AG: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 35 FMC Corporation: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 36 J.M.Huber Corporation: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 37 Merck Millipore: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 38 Roquette Group: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 39 The DOW Chemical Company: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)
TABLE 40 The Lubrizol Corporation: Company Snapshot (Business Description; Financial Information; Product Portfolio; News Coverage)