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Topical Excipients Market By Product (Inorganic Chemicals and Organic Chemicals), By Function (Buffers, Adsorbents, Permeation Enhancers, Surfactants, Stabilizers, Emulsifiers, Preservatives, Chelating Agents, Polymers, Humectants and Others) - Growth, Future Prospects & Competitive Analysis, 2017 – 2025

According to the World Health Organization's 2015 report, noncommunicable diseases account for 70% of chronic disease deaths, with communicable diseases accounting for the remaining 30%. Pharmaceutical industries are investing a huge amount of revenue in the formulation and development studies needed to deliver drugs effectively to the human body. Excipients are subjected to intense scrutiny and modification in order to achieve desired physical and chemical characterization of drug formulations.

In the product segment for topical excipients, inorganic chemicals, and organic chemicals are studied. The inorganic chemicals consist of calcium phosphate, calcium carbonate, calcium sulfate, magnesium stearate, metallic oxides, and others. Organic chemicals are segmented as starch, cellulose, petrochemicals, oleochemicals, and other organic chemicals. Starch is further sub-segmented as modified starch, dried starch, and converted starch. Cellulose includes cellulose ethers, microcrystalline cellulose, cellulose esters, CMC, and croscarmellose sodium. Petrochemicals considered topical excipients are glycols, povidones, mineral hydrocarbons, acrylic polymers, and other petrochemical excipients. Glycols consist of polyethylene glycol and propylene glycol.

Mineral hydrocarbons majorly comprise petrolatum, mineral waxes, and mineral oils. Oleochemicals are further categorized as fatty acids, mineral stearate, glycerin, and other oleochemical excipients. The excipients find different functions in drug formulation, such as buffers, adsorbents, permeation enhancers, surfactants, stabilizers, emulsifiers, preservatives, chelating agents, polymers, humectants, and others. Market estimation and data mining are performed for the product and function segments, respectively.

Cross-country sectional analysis is performed to understand the market trend of topical excipients at the regional level. 

There is tremendous diversity in the topical excipients that are used in drug formulation, and hence it is very important to understand the competition existing in the topical excipients market. A market assessment gives a brief idea regarding the latest trend in the preference of excipients for drug formulation. Company profiles will furnish the entire product range of the excipients and financial information about the companies. Manufacturers influencing the topical excipients market are Ashland, Inc., AkzoNobel, Roquette Group, BASF SE, J. M. Huber Corporation, The Dow Chemical Company, The Lubrizol Corporation, FMC Corporation, Evonik Industries AG, Merck Millipore, Associated British Foods Plc, Croda International Plc, Archer Daniels Midland Company, and others.

Based on product, the global topical excipients market is categorized into:

Inorganic Chemicals

    • Calcium Phosphate
    • Calcium Carbonate
    • Calcium Sulfate
    • Magnesium Stearate
    • Metallic Oxides
    • Others

Organic Chemicals

Starch

  • Modified Starch
  • Dried Starch
  • Converted Starch

Cellulose

  • Cellulose Ethers
  • Microcrystalline Cellulose
  • Cellulose Esters
  • CMC and croscarmellose sodium
  • Petrochemicals

Glycols

  • Polyethylene Glycols
  • Propylene Glycols
  • Povidones

Mineral Hydrocarbons

  • Petrolatum
  • Mineral Waxes
  • Mineral Oils
  • Acrylic Polymers
  • Other petrochemical excipients

Oleochemicals

  • Fatty Acids
  • Mineral Stearate
  • Glycerin
  • Other Oleochemical Excipients
  • Other Organic Chemicals (Aloe Vera, Vitamin E Oil, and Others)

Excipients are very important during the formulation of active pharmaceutical ingredients. It has an important role in delivering the drug into the human body. It has no medicinal properties but streamlines the production of drug molecules and promotes the physical absorption of drugs. They are useful in enhancing the physical properties of drug formulation, such as disintegration time, lubricant, flowability, taste masking, etc. Organic chemicals are the most frequently used excipients in drug formulation owing to their enhanced compatibility with active pharmaceutical ingredients. Organic chemicals have undergone technical modification during the novel drug delivery studies, thereby improving the flowability, drug absorption capacity, and disintegration time of the drug formulation. Inorganic chemicals, due to their inert nature, are mostly used as fillers and taste masking agents in drug formulation.

Manufacturers influencing the topical excipients market are Ashland, Inc., AkzoNobel, Roquette Group, BASF SE, J. M. Huber Corporation, The Dow Chemical Company, The Lubrizol Corporation, FMC Corporation, Evonik Industries AG, Merck Millipore, Associated British Foods Plc, Croda International Plc, Archer Daniels Midland Company, and others.

Based on function, the topical excipients market is categorized into:

  • Buffers
  • Adsorbents
  • Permeation Enhancers
  • Surfactants
  • Stabilizers
  • Emulsifiers
  • Preservatives
  • Chelating Agents
  • Polymers
  • Humectants
  • Others (co-solvents, preservatives, thickening agents, and smoothing agents)

On the basis of the functional properties of excipients, they are utilized for making solid, semisolid, and liquid drug formulations. Stabilizers and emulsifiers are mostly used in semisolid and liquid dosage forms. Stabilizers such as benzophenone and butylated hydroxytoluene derivatives are chemical moieties that prevent chemical, oxidative, and light-sensitive degradation of active pharmaceutical ingredients. Emulsifiers such as lecithin and taurocholic acid enhance the miscibility of oil-liquid and liquid-gas phases to promote product shelf life and attain smooth drug delivery.

Preservatives and buffers are mandatory excipients in a drug formulation as they preserve and protect the drug formulation from microbial contamination and drug deterioration due to changes in pH, which, if unchecked, would result in serious adverse effects. Surfactants are the subject of extensive research, with cationic surfactants being developed in various micelle concentrations to improve drug delivery. 

For the purpose of this study, the global topical excipients market is categorized into the following regional and country-specific markets:

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • France
    • Italy
    • U.K.
    • Russia
    • Rest of Europe
  • Asia-Pacific
    • India
    • China
    • Japan
    • Rest of Asia-Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East and Africa
    • GCC Countries
    • South Africa
    • Rest of Middle East and Africa

The Centers for Disease Control and Prevention state that in the United States, 7 in 10 people suffer from health complications and immediately require medical intervention. The rising prevalence of health complications and the domicile of market leaders manufacturing topical excipients buttress the growth of topical excipients in North America. Western Europe is a leader in the production of high-quality topical excipients, with pharmaceutical companies investing heavily in drug formulation accelerated stability testing studies. Asia Pacific is an attractive market destination for topical excipients on account of its large ailing population, huge production of generic drug formulation, and the establishment of major pharmaceutical players engaged in the production of branded drugs, which supports the Asian Pacific market's growth.

Frequently Asked Question:

The market for Topical Excipients Market is expected to reach USD$ 592.8 Mn in 2025.

The Topical Excipients Market is expected to see significant CAGR growth over the coming years, at 5.72 %.

The report is forecasted from 2017 -2025.

The base year of this report is 2016.

BASF SE, J. M. Huber Corporation, The Dow Chemical Company, The Lubrizol Corporation, FMC Corporation, Evonik Industries AG. are some of the major players in the global market.

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Trusted By
Godaddy
Published Date:  Jan 2018
Category:  Pharmaceuticals
Report ID:   58941
Report Format:   PDF
Pages:   120
Rating:    4.2 (28)
Delivery Time: 24 Hours to 48 Hours   
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