Bioengineered skin and soft tissue substitutes are generally derived from autologous or allogeneic human tissue, xenographic tissue, synthetic materials or a composite.These products being used and evaluated for treating a variety of conditions such as breast reconstruction, thermal injury treatment, plastic surgeries, lower extremity ulcers and others. Bioengineered and soft tissue substitutes can either be acellular or cellular. Acellular dermal matrix (ADM) contains a scaffold or a matrix of materials like hyaluronic acid, collagen and fibronectin. ADM products can be based in species sources, additives, hydration, tissue source, and preparation mode. Cellular products incorporate living cells such as keratinocytes and fibroblasts embedded in a matrix. Such cellular matter could be allogeneic, autologous or even derived from other species. Skin substitutes are usually composed of epidermal cells, dermal cells or a combination of both and provide as growth factors.
Non-healing wounds is a chief application area of bioengineered skin and skin substitute products. This area potentially included diabetic ulcers pressure ulcers and vascular insufficiency ulcers. Such wounds do not adequately heal with conventional wound care and may lead to prolonged morbidity and augmented risk of mortality. Bioengineered skin substitutes have the potential to improve healing rates in such treatments in a quicker time and reduce the risk of complications. Second and third degree burns can also be effectively treated with bioactive skin and skin substitutes.
The global bioengineered skin and skin substitutes market is segmented on the following bases:
Key players identified for bioengineered skin and skin substitutesmarket include but are not limited to:
LifeCell Corp., Bard Davol, Ethicon, LifeNet Health, Synthes, Tissue Regenix Wound Care, KCI, TEI Biosciences, Covidien plc, MiMedix, BioD,NuTech Medical, AlloSource, Medline Industries, Cook Biotech, Organogenesis, Shire Regenerative Medicine, Genzyme Biosurgery, Soluble Systems, Forticell Bioscience, Smith and Nephew, Integra LifeSciences, Advanced Tissue Sciences and several others.
This report offers: