Global Digital PCR Market

Market Insights

Digital Polymerase Chain Reaction (dPCR) is a technologically advanced version of traditional polymerase chain reaction (PCR). dPCR is a more sensitive and reliable technique with an improved ability to quantify the absolute amount of nucleic acid. It divides the sample into a large number of fragments, each containing either one or no template nucleic acid sequence.

The report titled “Global Digital PCR Market: Growth, Share, Opportunities, and Competitive Analysis, 2016–2023” offers strategic insights into the overall digital PCR market, along with the market size and estimates for the duration of 2016 to 2023. The said research study covers an in-depth analysis of multiple market segments based on types of components and services, types of applications, and different geographical regions. The components and services type segment studied for analyzing the overall digital PCR market is majorly segmented into dPCR instruments, reagents and consumables, dPCR software, and services. On the basis of the type of application, the digital PCR market is segmented into clinical applications, research applications, and forensic applications.

In order to help strategic decision-makers, the report also includes sections on the competitive profiling of the leading players in the digital PCR market and the attractive investment proposition and market positioning of key manufacturers. Other in-depth analysis provided in the report includes:

Geographically, the global digital PCR market is studied for the following regional markets:

• North America
  • US.
  • Canada
• Europe
  • Germany
  • France
  • UK.
  • Italy
  • Spain
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • South-east Asia
  • Rest of Asia Pacific
• Latin America
  • Brazil
  • Mexico
  • Rest of Latin America
• Middle East & Africa
  • GCC Countries
  • South Africa
  • Rest of the Middle East and Africa

The market size and forecast for these regional and country-level markets are presented in this study for the period 2013–2023. Market growth rates for the forecast period 2016–2023 are also included in this report, considering 2015 as the base year.

Along with quantitative information, qualitative information sets and assessment tools are provided in this study for a better analysis of the overall market scenario and future prospects. Information such as market inclination insights and drivers, challenges, and opportunities assists the readers in understanding the ongoing trends in the global digital PCR market. Tools such as the market positioning of key players and an attractive investment proposition provide the readers with insights into the competitive scenario of the global digital PCR market. This report concludes with a company profiles section that highlights major information about the key players engaged in the global digital PCR market. In-depth competitive environment analysis and historical years (2013 and 2014) of market size data are also provided in the report.

Thus, the research study provides a holistic view of the global digital PCR market, offering market size and estimates for the period from 2016 to 2023, keeping in mind the above-mentioned factors.

Based on the type of application, the digital PCR market is segmented as follows:

• Clinical Application
• Research Application
• Forensic Application

Digital PCR techniques have paved the way for innovation in molecular diagnostics and life sciences research through their most potential features, such as the absolute detection and quantification of genetic materials such as DNA and RNA. The digital PCR industry has been experiencing an upward trend with a swift growth rate despite the economic turmoil, hence promising positive growth potential. The global digital PCR market is segmented by applications, such as clinical applications, research applications, and forensics applications. The research segment held the largest share of the overall digital PCR market by applications. The rising applications in drug discovery and biomarker discovery for cancer treatment are driving the research application segment. The forensics application is anticipated to grow at the highest CAGR during the forecast period owing to the growing need for effective and quick results in crime investigation using available resources. This has driven the digital PCR application in forensics applications.

Based on the type of components and services, the digital PCR market is segmented as follows:

• dPCR Instruments
• Reagents and consumables
• PDC software and services

Digital PCR is among the most powerful technologies in molecular biology. It enables us to produce millions of copies of DNA sequences in the quickest possible time. PCR is an indispensable tool used in medical and biotechnology research across applications such as DNA cloning, functional analysis of viral, bacterial, and human genes, forensic science, and the diagnosis of hereditary diseases and beyond. The digital PCR industry has been experiencing an upward trend with a swift growth rate despite the economic turmoil, hence promising positive growth potential. In recent years, this gene amplification technology has been significantly supported by the growing demand for molecular diagnostics. On the basis of components and services, the global digital PCR market is segmented into dPCR instruments, reagents, consumables, and dPCD software and services. Being the most frequently used and replenished component in dPCR, the reagents segment is estimated to have a significant market share. Moreover, it is also expected that the segment will progress at a rapid CAGR over the forecast period. Some of the key products in this segment include amplification reagents, primers, probes, and panels; plastic and glass consumables; plates; and reaction vessels.

For the purpose of this study, the global digital PCR market is categorized into three segments:

• North America
• Europe
• Asia Pacific
• Latin America (LATAM)
• Middle East and Africa (MEA)

According to the current market scenario, North America is the largest regional market for dPCR technology. The highest market share of the region is attributed to the existence of evolved healthcare and biotechnology research infrastructure, the swift entry of novel products into the U.S. market, and favorable private and public funding in research and development. In addition, initiatives are taken by local governments to enhance public healthcare by introducing novel drugs to the public, significantly contributing to the dominance of this region. Among the products and services, reagents and consumables account for the largest contribution to market revenue. Increasing R&D activities and academic research will further heighten the demand for reagents and consumables. Asia Pacific is expected to be the fastest-growing market during the forecast period. The competitors in the Asia Pacific dPCR market are budding and are perpetually working on introducing new clinical uses to augment the value of dPCR technology. Some prime factors attributed to the progress of the Asia Pacific market include the rapid entry of market leaders in the region, the escalating status of Asia Pacific as a hub for CRO and CMO activities, and the rapid evolution of healthcare and life sciences research infrastructure.

Chapter 1 Preface 10
1.1 Report Description 10
1.1.1 Purpose of the Report 10
1.1.2 Target Audience 10
1.1.3 USP and Key Offerings 10
1.2 Research Scope 11
1.3 Research Methodology 12
1.3.1 Phase I – Secondary Research 12
1.3.2 Phase II – Primary Research 13
1.3.3 Phase III – Expert Panel Review 13
1.3.4 Assumptions 14

Chapter 2 Executive Summary 15
2.1 Global Digital PCR Market Portraiture 15
2.2 Global Digital PCR Market, by Type of Component, 2015 (USD Mn) 16
2.3 Global Digital PCR Market, by Type of Application, 2015 (USD Mn) 17
2.4 Global Digital PCR Market, by Geography, 2015 (Value %) 18

Chapter 3 Global Digital PCR Market Overview 20
3.1 Overview 20
3.2 Market Drivers 21
3.2.1 Technological advancements in chip and droplet based dPCR are assisting growth of dPCR market 21
3.2.2 Significant development in the field of personalized medicine and targeted drug monitoring is increasing the demand of dPCR in research applications 22
3.3 Market Restraints 22
3.3.1 Lack of awareness related to the potential of dPCR in developing and underdeveloped countries 22
3.3.2 High installation costs of dPCR are expected to restraint the market growth 23
3.4 Market Opportunities 24
3.4.1 Shift From Plant-Derived to Genome-Based Drug Discovery is key opportunity in dPCR market 24
3.5 Attractive Investment Proposition 24
3.6 Market Competition Assessment: Digital PCR, by Key Players 26

Chapter 4 Global Digital PCR Market, By Components and Services 27
4.1 Preface 27
4.2 dPCR Instruments 28
4.3 Reagents and Consumables 29
4.4 dPCR Software and Services 30

Chapter 5 Global Digital PCR Market Analysis, by Applications 31
5.1 Introduction 31
5.2 Clinical Applications 32
5.3 Research Applications 33
5.4 Forensics Applications 35

Chapter 6 Global Digital PCR Market, By Geography 37
6.1 Preface 37
6.2 North America (U.S. & Canada) 38
6.3 Europe (U.K., Germany & Rest of Europe) 38
6.4 Asia Pacific (China, Japan and Rest of APAC) 39
6.5 Latin America (Mexico, Brazil and Rest of LATAM) 40
6.6 Middle East and Africa 41

Chapter 7 Company Profiles for Digital PCR 43
7.1 Thermo Fischer Scientific, Inc. 43
7.1.1 Thermo Fischer Scientific, Inc.: Company Snapshot (Business Description; Financial Information; Product Position/Portfolio; News Coverage) 43
7.2 Bio-Rad Laboratories, Inc. 45
7.2.1 Bio-Rad Laboratories, Inc.: Company Snapshot (Business Description; Financial Information; Product Position/Portfolio; News Coverage) 45
7.3 Fluidigm Corporation 47
7.3.1 Fluidigm Corporation: Company Snapshot (Business Description; Financial Information; Product Position/Portfolio; News Coverage) 47
7.4 Raindance Technologies, Inc. 48
7.4.1 Raindance Technologies, Inc.: Company Snapshot (Business Description; Financial Information; Product Position/Portfolio; News Coverage) 48
7.5 Sigma-Aldrich Corporation 49
7.5.1 Sigma-Aldrich Corporation: Company Snapshot (Business Description; Financial Information; Product Position/Portfolio; News Coverage) 49
7.6 BIOKÉ 51
7.6.1 BIOKÉ: Company Snapshot (Business Description; Financial Information; Product Position/Portfolio; News Coverage) 51

Chapter 8 Company Profiles for Other PCR system and components 52
8.1 F. Hoffmann-La Roche Ltd. 52
8.1.1 F. Hoffmann-La Roche Ltd.: Company Snapshot (Business Description; Financial Information; Product Position/Portfolio; News Coverage) 52
8.2 Qiagen N.V. 54
8.2.1 Qiagen N.V.: Company Snapshot (Business Description; Financial Information; Product Position/Portfolio; News Coverage) 54
8.3 Agilent Technologies, Inc. 56
8.3.1 Agilent Technologies, Inc.: Company Snapshot (Business Description; Financial Information; Product Position/Portfolio; News Coverage) 56
8.4 Takara Bio, Inc. 58
8.4.1 Takara Bio, Inc.: Company Snapshot (Business Description; Financial Information; Product Position/Portfolio; News Coverage) 58
8.5 Biomérieux S.A. 60
8.5.1 Biomérieux S.A.: Company Snapshot (Business Description; Financial
Information; Product Position/Portfolio; News Coverage) 60
8.6 Affymetrix, Inc. 62
8.6.1 Affymetrix, Inc.: Company Snapshot (Business Description; Financial
Information; Product Position/Portfolio; News Coverage) 62
8.7 Promega Corporation 64
8.7.1 Promega Corporation: Company Snapshot (Business Description; Financial Information; Product Position/Portfolio; News Coverage) 64
8.8 GE Healthcare 66
8.8.1 GE Healthcare: Company Snapshot (Business Description; Financial Information; Product Position/Portfolio; News Coverage) 66
8.9 Integrated DNA Technologies, Inc. 68
8.9.1 Integrated DNA Technologies, Inc.: Company Snapshot (Business Description; Financial Information; Product Position/Portfolio; News Coverage) 68
8.10 MDxHealth 68
8.10.1 MDxHealth: Company Snapshot (Business Description; Financial Information; Product Position/Portfolio; News Coverage) 69

List of Figures

FIG. 1 Digital PCR Market: Research Methodology 12
FIG. 2 Global Digital PCR Market, by Type of Component, 2015 (USD Mn) 16
FIG. 3 Global Digital PCR Market, by Type of Application, 2015 (USD Mn) 17
FIG. 4 Global Digital PCR Market, by Geography, 2015 (Value %) 18
FIG. 5 Attractive Investment Proposition, by Geography, 2015 25
FIG. 6 dPCR Instruments Market, 2013 – 2023 (USD Mn) 28
FIG. 7 dPCR Reagents and Consumables Market, 2013 – 2023 (USD Mn) 29
FIG. 8 dPCR Software and Services Market, 2013 – 2023 (USD Mn) 30
FIG. 9 Clinical Applications Market, 2013 – 2024 (USD Mn) 33
FIG. 10 Research Applications Market, 2013 – 2023 (USD Mn) 35
FIG. 11 Forensics Applications Market, 2013 – 2023 (USD Mn) 36
FIG. 12 North America Digital PCR Market, by Country, 2013 – 2023 (USD Mn) 38
FIG. 13 Europe Digital PCR Market, by Country, 2013 – 2023 (USD Mn) 39
FIG. 14 Asia Pacific Digital PCR Market, by Country, 2013 – 2023 (USD Mn) 40
FIG. 15 Latin America Digital PCR Market, 2013 – 2023 (USD Mn) 41
FIG. 16 Middle East and Africa Digital PCR Market, 2013 – 2023 (USD Mn) 42

List of Tables

TABLE 1 Market Competition Assessment: Digital PCR, by Key Players 26
TABLE 2 Global Digital PCR Market, by Components and Services, 2013 – 2023 (USD Mn) 27
TABLE 3 Global Digital PCR Market, by Applications, 2013 – 2023 (USD Mn) 32
TABLE 4 Global Digital PCR Market, by Geography, 2013 – 2023 (USD Mn) 37
TABLE 5 Thermo Fischer Scientific, Inc.: Company Snapshot (Business Description;
Financial Information; Product Position/Portfolio; News Coverage) 43
TABLE 6 Bio-Rad Laboratories, Inc.: Company Snapshot (Business Description; Financial
Information; Product Position/Portfolio; News Coverage) 45
TABLE 7 Fluidigm Corporation: Company Snapshot (Business Description; Financial
Information; Product Position/Portfolio; News Coverage) 47
TABLE 8 Raindance Technologies, Inc.: Company Snapshot (Business Description;
Financial Information; Product Position/Portfolio; News Coverage) 48
TABLE 9 Sigma-Aldrich Corporation: Company Snapshot (Business Description; Financial
Information; Product Position/Portfolio; News Coverage) 49
TABLE 10 BIOKÉ: Company Snapshot (Business Description; Financial Information; Product
Position/Portfolio; News Coverage) 51
TABLE 11 F. Hoffmann-La Roche Ltd.: Company Snapshot (Business Description; Financial
Information; Product Position/Portfolio; News Coverage) 52
TABLE 12 Qiagen N.V.: Company Snapshot (Business Description; Financial Information;
Product Position/Portfolio; News Coverage) 54
TABLE 13 Agilent Technologies, Inc.: Company Snapshot (Business Description; Financial
Information; Product Position/Portfolio; News Coverage) 56
TABLE 14 Takara Bio, Inc.: Company Snapshot (Business Description; Financial Information;
Product Position/Portfolio; News Coverage) 58
TABLE 15 Biomérieux S.A.: Company Snapshot (Business Description; Financial Information;
Product Position/Portfolio; News Coverage) 60
TABLE 16 Affymetrix, Inc.: Company Snapshot (Business Description; Financial Information;
Product Position/Portfolio; News Coverage) 62
TABLE 17 Promega Corporation: Company Snapshot (Business Description; Financial
Information; Product Position/Portfolio; News Coverage) 64
TABLE 18 GE Healthcare: Company Snapshot (Business Description; Financial Information;
Product Position/Portfolio; News Coverage) 66
TABLE 19 Integrated DNA Technologies, Inc.: Company Snapshot (Business Description;
Financial Information; Product Position/Portfolio; News Coverage) 68
TABLE 20 MDxHealth: Company Snapshot (Business Description; Financial Information;
Product Position/Portfolio; News Coverage) 69