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Liquid Biopsy Market

Liquid Biopsy Market By Analytes (Circulating Tumor Cells (CTCs), Circulating Tumor Dna (CtDNA), Extracellular Vesicles (EVs)), By Application (Prognosis, Diagnosis, Therapy Monitoring) – Market Growth, Future Prospects and Competitive Analysis, 2016 – 2022
Report Book

Published Date: May 2016
Category: Biotechnology
Report ID: 57830
Report Format: PDF
No of Pages: 190

Rating: Credence Reports

Market Insights

Biomarker-based diagnostics have already offered great advances in cancer diagnosis, prognosis, staging, and therapy selection in the past decade. However, the tissue-based detection approach produces a major drawback in terms of invasion for sample collection. Over the last few years, several cancer biomarker research studies have moved their focus to the analysis of biomarkers found in biological fluids, which offer minimal invasion and longer disease tracking – liquid biopsy. As a result, several cancer diagnostic companies and startups have accepted the challenge of commercializing liquid biopsy tools in the market.

For this study, the liquid biopsy market is studied by analytes and applications. Based on analytes, this report studies circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), and extracellular vesicle (SV) segments. Liquid biopsy techniques find application in cancer prognosis, diagnosis, and therapy monitoring. This report provides market size and forecast (USD Mn) for such considered segments for 2014-2022, along with their respective CAGRs (value %) for 2016-2022, considering 2015 as the base year.

Geographically, the global liquid biopsy market is categorized into the following regional markets:

  • North America
    • US.
    • Canada
  • Europe
    • Germany
    • France
    • UK.
    • Italy
    • Spain
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • South-east Asia
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • GCC Countries
    • South Africa
    • Rest of the Middle East and Africa

The market size and forecast for the period 2014-2022, along with the CAGRs for the period 2016-2022 for the mentioned segments, are also presented in this study.

This study also provides qualitative assessment tools for the readers that offer the overall status and trends in the liquid biopsy market. Such sections include market dynamics (drivers, challenges, prospects), major commercial events, and major research events. In addition, for competitive assessment, tools such as attractive investment proposition and fractal map analysis (by key market players) are also presented in this study. Finally, this report concludes with a company profiles section that highlights major information about key companies operating in the liquid biopsy market. Some of the major market players covered in this section include Myriad Genetics, Qiagen, Trovagene, Natera, Foundation Medicine, and others. The key information provided on these players is based on parameters such as business description, financial health, product portfolio, and news coverage.

Based on the analyte types, the global liquid biopsy market is classified as follows:

  • Circulating Tumor Cells (CTCs)
  • Circulating Tumor DNA (ctDNA) Fragments
  • Extracellular Vesicles (EVs)

Among the mentioned analyte types, CTCs demonstrate the longest history of being subject to liquid biopsy. CTC-based technologies have been in practice for over a decade, and their IVD use has FDA approval. ctDNA is a more recent entrant in the liquid biopsy market and is rapidly becoming an alternative to CTC assays. EVs, furthermore, are the latest addition to the liquid biopsy portfolio and are the least developed so far. Approximately a third of the overall liquid biopsy research is concentrated on EV development. EVs represent a set of the source of circulating biomarkers in lipid coat encapsulation. The biomarker cargo associated with EVs includes exosomes, microvesicles, apoptotic bodies, large oncosomes, and others.

The application areas studied for analyzing the liquid biopsy market are:

  • Prognosis
  • Diagnosis
  • Therapy monitoring
  • Others

Liquid biopsy can assist clinicians in determining cancer prognosis, stratification of patients to determine the best possible treatment modality, and assess tumor resistance mechanisms. Molecular characterization of tumors is facilitated through liquid biopsy, and its non-invasive nature paves the way for repeated sampling to scrutinize genetic changes during any period by avoiding tissue biopsy. Disease prognosis currently takes the highest share in the liquid biopsy applications market, whereas diagnostics and therapy monitoring closely competes with each other. Liquid biopsy can efficiently monitor the effectiveness of the treatment regimen, thus facilitating treatment optimization and possible alterations. As the nature of tumors changes over time, liquid biopsy offers the benefit of analyzing such dynamics and providing information for possible treatment change. In cases where particular genotypes are identified in patients, liquid biopsy allows early detection of cancer before the occurrence of overt symptoms.

Based on geographical segmentation, the global liquid biopsy market is studied for:

North America is the current geographical leader in the liquid biopsy market. High demand for the latest diagnostic modules, coupled with greater awareness between both patients and caregivers, plays a vital growth in the dominance of this region. Additionally, several giant market players and new startups operating in this market are domiciled in North America and Europe, thus allowing early bird advantage to these regions. A large number of research activities being conducted in the region also is a prime phenomenon in North American and Europe markets. However, challenged reimbursements may hold back the growth of this market to a certain extent. The introduction of cost-effective solutions and rapid approvals in Latin America and Asia-Pacific will serve as the prime growth drivers in these regions.

Chapter 1 Preface
1.1 Report Description
1.2 Market Segmentation
1.3 Research Methodology

Chapter 2 Executive Summary
2.1 Liquid Biopsy Market Share, by Analytes, 2015 (Value %)
2.2 Liquid Biopsy Market, by Applications, 2015 (USD Mn)
2.3 Liquid Biopsy Market Share, by Geography, 2015 (Value %)

Chapter 3 Liquid Biopsy Market: Market Dynamics and Outlook
3.1 Introduction
3.2 Major Commercial Events
3.3 Major Research Events
3.4 Drivers
3.5 Challenges
3.6 Future Prospects
3.7 Attractive Investment Proposition
3.1 Competitive Analysis: Fractal Map Investigation, by Key Market Players

Chapter 4 Global Liquid Biopsy Market Analysis, by Analytes
4.1 Preface
4.2 Circulating Tumor Cells (CTCs)
4.3 Circulating Tumor DNA (ctDNA)
4.4 Extracellular Vesicles (EVs)

Chapter 5 Global Liquid Biopsy Market Analysis, by Application
5.1 Preface
5.2 Prognosis
5.3 Diagnosis
5.4 Therapy Monitoring
5.5 Others

Chapter 6 Global Liquid Biopsy Market, by Geography
6.1 Preface
6.2 North America
6.2.1 U.S.
6.2.2 Canada
6.3 Europe
6.3.1 U.K.
6.3.2 Germany
6.3.3 Rest of Europe
6.4 Asia-Pacific
6.4.1 Japan
6.4.2 China
6.4.3 Rest of Asia-Pacific
6.5 Middle East and Africa (MEA)
6.6 Latin America

Chapter 7 Company Profiles
7.1 Myriad Genetics
7.1.1 Business Description
7.1.2 Financial Health and Budget Allocation
7.1.3 Product Positions/Portfolio
7.1.4 News Coverage
7.2 Oncocyte
7.2.1 Business Description
7.2.2 Financial Health and Budget Allocation
7.2.3 Product Positions/Portfolio
7.2.4 News Coverage
7.3 RainDance Technologies
7.3.1 Business Description
7.3.2 Financial Health and Budget Allocation
7.3.3 Product Positions/Portfolio
7.3.4 News Coverage
7.4 Veracyte
7.4.1 Business Description
7.4.2 Financial Health and Budget Allocation
7.4.3 Product Positions/Portfolio
7.4.4 News Coverage
7.5 Foundation Medicine
7.5.1 Business Description
7.5.2 Financial Health and Budget Allocation
7.5.3 Product Positions/Portfolio
7.5.4 News Coverage
7.6 Genomic Health
7.6.1 Business Description
7.6.2 Financial Health and Budget Allocation
7.6.3 Product Positions/Portfolio
7.6.4 News Coverage
7.7 Biocept
7.7.1 Business Description
7.7.2 Financial Health and Budget Allocation
7.7.3 Product Positions/Portfolio
7.7.4 News Coverage
7.8 Natera
7.8.1 Business Description
7.8.2 Financial Health and Budget Allocation
7.8.3 Product Positions/Portfolio
7.8.4 News Coverage
7.9 Qiagen
7.9.1 Business Description
7.9.2 Financial Health and Budget Allocation
7.9.3 Product Positions/Portfolio
7.9.4 News Coverage
7.10 Trovagene
7.10.1 Business Description
7.10.2 Financial Health and Budget Allocation
7.10.3 Product Positions/Portfolio
7.10.4 News Coverage
7.11 Others
7.11.1 Business Description
7.11.2 Financial Health and Budget Allocation
7.11.3 Product Positions/Portfolio
7.11.4 News Coverage

List of Figures

FIG. 1 Liquid Biopsy: Market Segmentation
FIG. 2 Liquid Biopsy Market Share, by Analytes, 2015 (Value %)
FIG. 3 Liquid Biopsy Market, by Analytes, 2015 (USD Mn)
FIG. 4 Liquid Biopsy Market Share, by Geography, 2015 (Value %)
FIG. 5 Attractive Investment Proposition, Liquid Biopsy Market, 2015
FIG. 6 Competitive Analysis: Fractal Map Investigation, by Key Market Players
FIG. 7 Global CTC Based Liquid Biopsy Market, 2014 – 2022 (USD Mn)
FIG. 8 Global ctDNA Based Liquid Biopsy Market, 2014 – 2022 (USD Mn)
FIG. 9 Global Extracellular Vesicles Based Liquid Biopsy Market, 2014 – 2022 (USD Mn)
FIG. 10 Global Liquid Biopsy for Disease Prognosis Market, 2014 – 2022 (USD Mn)
FIG. 11 Global Liquid Biopsy for Disease Diagnosis Market, 2014 – 2022 (USD Mn)
FIG. 12 Global Liquid Biopsy for Therapy Monitoring Market, 2014 – 2022 (USD Mn)
FIG. 13 Global Liquid Biopsy for Other Applications Market, 2014 – 2022 (USD Mn)
FIG. 14 U.S. Liquid Biopsy Market, 2014 – 2022 (USD Mn)
FIG. 15 Canada Liquid Biopsy Market, 2014 – 2022 (USD Mn)
FIG. 16 U.K. Liquid Biopsy Market, 2014 – 2022 (USD Mn)
FIG. 17 Germany Liquid Biopsy Market, 2014 – 2022 (USD Mn)
FIG. 18 Rest of Europe Liquid Biopsy Market, 2014 – 2022 (USD Mn)
FIG. 19 Japan Liquid Biopsy Market, 2014 – 2022 (USD Mn)
FIG. 20 China Liquid Biopsy Market, 2014 – 2022 (USD Mn)
FIG. 21 Rest of Asia-Pacific Liquid Biopsy Market, 2014 – 2022 (USD Mn)
FIG. 22 Middle East and Africa Liquid Biopsy Market, 2014 – 2022 (USD Mn)
FIG. 23 Latin America Liquid Biopsy Market, 2014 – 2022 (USD Mn)

List of Tables

TABLE 1 Global Liquid Biopsy Market, by Components, 2014 – 2022 (USD Mn)
TABLE 2 Global Liquid Biopsy Market, by Application, 2014 – 2022 (USD Mn)
TABLE 3 Global Liquid Biopsy Market, by Geography, 2014 – 2022 (USD Mn)
TABLE 4 North America Liquid Biopsy Market, by Country, 2014 – 2022 (USD Mn)
TABLE 5 Europe Liquid Biopsy Market, by Country, 2014 – 2022 (USD Mn)
TABLE 6 Asia-Pacific Liquid Biopsy Market, by Country, 2014 – 2022 (USD Mn)

Frequently asked questions :

What is the size of Liquid Biopsy Market?

The market for Liquid Biopsy Market is expected to reach US$ 10,850.3 Mn By 2022

What is the Liquid Biopsy Market CAGR?

The Liquid Biopsy Market is expected to see significant CAGR growth over the coming years, at 24.7%.

What is the Forecast period considered for Liquid Biopsy Market?

The report is forecasted from 2016-2022.

What is the base year considered for Liquid Biopsy Market?

The base year of this report is 2021.

Who are the major players in this market?

Myriad Genetics, Oncocyte, RainDance Technologies, Veracyte, Foundation Medicine,are some of the major players in the global market.

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