Home / Chemicals / Phylloquinone Market by Grade (Food Grade, Pharmaceutical Grade) by Route of Administration (Parental, Oral, Topical) by Application (Vitamin K deficiency, Warfarin overdose, Obstructive jaundice, Osteoporosis, Others) - Growth, Future Prospects And Competitive Analysis, 2016 - 2028

Phylloquinone Market by Grade (Food Grade, Pharmaceutical Grade) by Route of Administration (Parental, Oral, Topical) by Application (Vitamin K deficiency, Warfarin overdose, Obstructive jaundice, Osteoporosis, Others) - Growth, Future Prospects And Competitive Analysis, 2016 - 2028

Published Date: Mar 2022
Report ID: 60524
Report Format: PDF
Pages: 128
Rating: 4.2 (21)

Phylloquinone Market Analysis

Phylloquinone is also widely known as Vitamin K or Phytomenadione is generally found in food and usually taken as a dietary supplement. Phylloquinone is quite effective in treatment of some disorders which includes vitamin k deficiency, obstructive jaundice and warfarin overdose. Phylloquinone is generally taken as oral supplement or sometime may be parental and topical. However, consumption of Phylloquinone is associated with certain side effects such as pain at the site of injection and alteration of taste. Exceptionally it may cause severe allergic reaction.

Global Phylloquinone market is expected to witness CAGR of 7.95% during the forecast period. The revenue generated by the global Phylloquinone market in 2021 was over USD 483.92 million and expected to generate revenue worth USD 880.66 million in 2028. The incremental growth opportunity offered by the global Phylloquinone is estimated to be USD 4.96 billion between 2022 and 2028.     


Interesting Facts about Phylloquinone Industry

  • Green leafy vegetables are main source of Phylloquinone
  • Phylloquinone is highly beneficial in bleeding disorder
  • Major health concerns associated with Phylloquinone are related to injectables phytonadione
  • Vitamin K deficiency is more common in infants
  • Currently over 200 million people are suffering from osteoporosis

Changing Lifestyle Causing Vitamin K Deficiency

Vitamin K deficiency, Warfarin overdose, Obstructive jaundice, Osteoporosis, Others are major applications of Phylloquinone. Vitamin K deficiency is leading application of Phylloquinone with over 40% share in 2021. Rapidly changing lifestyle and food habits are resulting into vitamin k deficiency in developed as well as emerging countries. Increasing trend of junk food and decreasing consumption of green leafy vegetables causing chronic diseases among people owing to vitamin deficiencies. Phylloquinone is very crucial for restoring the vitamin k level in the body as it is fat absorbable and important for bone and dental health. Additionally, it plays vital role in blood clotting and very important in bleeding disorders. This in turn driving the demand for Phylloquinone.

Pharmaceutical Grade of Phylloquinone to Dominate the Demand with over 75% share

Food Grade, and Pharmaceutical Grade are two major grades of Phylloquinone. Pharmaceutical grade of Phylloquinone dominate the demand with over 75% share in 2021. Pharma grade Phylloquinone is growing in demand owing to ever increasing incidences of vitamin d deficiency and rise in chronic diseases related to bleeding. While, food grade Phylloquinone is also expected to increase in its share by growing at a lucrative CAGR over the forecast period.

Oral Dosage of Phylloquinone to Rule the Industry

Parental, Oral and Topical are major routes of administration of Phylloquinone in human body. Oral administration is dominating the industry with over 60% share in total Phylloquinone consumed in 2021. While, topical administration also hold the significant share in 2021. However, there are certain side effects associated with the topical administration such as pain, dizziness, low blood pressure, cyanosis, etc. In light with this, oral supplement of Phylloquinone is likely to grow at a rapid pace as compare to other two types of administration.

Strong Focus on Research & Development

Shandong Guangtongbao Pharmaceuticals, Anhui Wanhe Pharmaceutical, Nutrilo, DSM, Yongan Pharmceutical, Zhejiang Chengyi Pharmaceutical and BASF SE are major players operating in the global Phylloquinone market. All prominent players are highly focused on Research and Development activities in order to develop most effective products. Major focus of R&D activities is focused on exploration of role of vitamin k into infants, adults and geriatric population. Moreover, studies are also researching the bioavailability and absorption of Phylloquinone into intestine and its effect on metabolism. Moreover, increasing incidence if bleeding disorders is forcing companies to develop more effective solution to treat these disorders using vitamin k. This in turn will trigger the demand for Phylloquinone in the years to come.

Phylloquinone Market Dominated by Europe and North America

Global Phylloquinone market is dominated by the Europe and North America collectively with around two third share in total revenue generation in 2021. North America lead the demand with majority of the consumption in 2021. While, Europe Phylloquinone market is triggered by the strong and consistent growth in Germany, UK and France. While, Asia Pacific market for Phylloquinone is mainly mobilized by the rising demand from China, Japan, South Korea, Singapore, Taiwan and India. Huge untapped potential and large population suffering from disorders that demand for vitamin k  supplement in the region market it most lucrative market for the future growth of Phylloquinone industry. It is also expected to exhibit robust CAGR of over 8% during the forecast period.

Frequently asked questions about global Phylloquinone industry

Unlike other industries, COVID 19 also taken a toll on Phylloquinone market with around 10.41% decline in its revenue growth rate in 2020 as compare to 2019

North America is the largest regional market with highest share in the total revenue generation of Phylloquinone consumed in 2021

Increasing incidence rate of vitamin k deficiency in Europe and North America is mainly fuelling the demand for Phylloquinone

Pharmaceutical Grad segment dominated the Phylloquinone market in 2021 with over 75% share

Oral was the largest segment of Phylloquinone by mounting in 2021 with over 60% share

Phylloquinone Report Scope

Report Attribute Details
Market Value in 2021 USD 483.92 million
Market Value in 2028 USD 880.66 million
CAGR 7.95% between 2022 and 2028
Benchmarking Year 2021
Past data 2016 – 2021
Forecast period 2022 – 2028
Segments covered


Food Grade

Pharmaceutical Grade

Route of Administration





Vitamin K deficiency

Warfarin overdose

Obstructive jaundice



Regional scope North America (U.S., Canada and Mexico), Europe (Russia, Spain, Italy, Germany, France, UK, Poland, Belgium, Netherland, Sweden, Denmark, Austria, etc.), Asia Pacific (India, South Korea, China, Japan, Taiwan, Singapore, Vietnam, Thailand, Indonesia, Malaysia, Australia, etc.), Latin America (Peru, Chile, Colombia, Brazil, Argentina, etc.), Middle East (KSA, UAE, Israel, etc.) & Africa (Egypt, Nigeria, South Africa, East African Community, etc.)
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