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Pyrogen Testing Market By Test Type (Attractive Investment Proposition, Rabbit Pyrogen Test (RPT), Limulus Amoebocyte Lysate (LAL) Assay, Chromogenic Tests, Turbidimetric Tests, Gel Clot Tests), By Product, By Application - Growth, Future Prospects, And Competitive Analysis, 2017 - 2025

Pyrogens are a heterogeneous group of microbial and non-microbial substances that cause fever. Lipopolysaccharides and endotoxins are the most common and potent variants; gram-positive bacteria are also a source of pyrogens. Since contamination from pyrogens in biotherapeutics, medical devices, pharmaceuticals, and cosmetics can possibly compromise health and well-being, it is mandatory for manufacturers to check on the limit of pyrogen.

The purpose of this research study titled "Pyrogen Testing Market: Growth, Future Prospects, and Competitive Analysis, 2017–2025" is to provide investors, developers, company executives, and industry participants with in-depth analysis to allow them to take strategic initiatives and decisions related to the prospects in the global pyrogen testing market. This report presents and analyses the major trends prevalent in the global pyrogen testing market and provides market size and forecast.

This report categorizes the global pyrogen testing market in terms of test type, products, applications, and geographical distribution. Based on test type, the global pyrogen testing market is categorized into rabbit pyrogen testing (RPT), Limulus amoebocyte lysate (LAL) assay (chromogenic tests, turbidimetric tests, and gel clot tests), and monocyte activation testing (MAT) (in vitro test). Reagents and kits, instruments and systems, and services are the products and solutions considered for the purpose of this study. Additionally, based on applications, the global pyrogen testing market is categorized into pharmaceutical and biotech manufacturing, medical device manufacturing, and others. The market size and forecast for each mentioned segment for the period 2015–2025 are presented in the report, along with respective CAGRs for the forecast duration of 2017–2025.

Geographically, the global pyrogen testing market is best understood by categorizing it into five major regions and five major region-level markets, as follows:

North America

  • U.S.
  • Canada

Europe

  • U.K.
  • Germany
  • Rest of Europe

Asia Pacific

  • China
  • Japan
  • Rest of Asia Pacific

Latin America

  • Brazil
  • Mexico
  • rest of Latin America

Middle East and Africa

  • GCC
  • Rest of the Middle East and Africa

The market size and forecast of each considered geographical market are presented for the perioad 2015–2025, along with CAGRs for the forecast period 2017–2025, and further cross-sectional analysis is presented in terms of products, test types, applications, and constituent region/country level markets.This report also includes qualitative assessment factors such as market dynamics (drivers, restraints, and opportunities) to have a good understanding of the current and anticipated trends in the global pyrogen testing market. Competition assessment tools such as market attractiveness assessment and competitive landscape analysis by key players are also demonstrated in the study.

Furthermore, this report concludes with a profile of key market players currently enjoying prominent positions in the pyrogen testing market. The key players profiled in this report are Associates of Cape Cod, Inc., Charles River Laboratories, Inc., Ellab A/S, GenScript, Hyglos GMBH (bioMérieux), Lonza Group, Merck KGaA (Merck Millipore), Sigma-Aldrich Corporation, Thermo Fisher Scientific, Inc., Wako Chemicals USA, Inc. (Pyrostar), and WUXI Pharmatech, Inc.

The global pyrogen testing market is studied for the following test types:

  • Rabbit Pyrogen Test (RPT)
  • Limulus Amoebocyte Lysate (LAL) Assay
  • Chromogenic Tests
  • Turbidimetric Tests
  • Gel-Clot Tests
  • Monocyte Activation Test (MAT) (in vitro test)

Among the considered test types, the rabbit pyrogen test and LAL tests are the most widely known. Monocyte activation testing is an in vitro method that is newer to the industry. Because this method is based on human fever reactions, the results are very similar to human situations. The protocol for RPT was first introduced in 1942; however, recent concerns around animal welfare and the risk of result variability are urging users to consider other alternatives. It is observed that LAL tests are continuously replacing RBTs and are being recommended by pharma companies and international bodies. However, in reported cases such as testing for the hepatitis B vaccine, the use of RBT is still recommended. It is also suggested that the use of RBT is justified only when other test types cannot be validated.

The global pyrogen testing market is studied for the following product types:

  • Reagents and Kits
  • Instruments and systems
  • Services

Reagents and kits form the largest revenue-generating segment for pyrogen testing, followed by instruments. The extensive requirement of consumables for research, supported by large-scale research and development and drug discovery activities taking place in the market due to the growing need for breakthrough drugs and medical devices, is the main growth driver of this segment. On the other hand, increasing pressure to ensure good manufacturing practices and continuous technological innovation has pushed the need to replace obsolete instruments, supporting the demand for new pyrogen testing instruments. Additionally, growing CRO activities have led to the rise of several new testing establishments, which further support the demand for instruments and equipment, along with testing services.

For the purpose of this study, the global pyrogen testing market is studied for its application in the following applications:

  • Manufacturing of pharmaceuticals and biotech products
  • Medical Device Manufacturing
  • Others

Pharmaceutical and biotechnology manufacturing is the largest revenue-generating application segment in the global pyrogen testing market. Since the R&D activities of the pharma and biotech industries have plummeted, several new trends in these industries are being observed. With the incidence of chronic diseases increasing, there is increasing pressure on pharmaceutical manufacturers to come up with novel drugs. The demand for medicines is rapidly growing in emerging countries and economies that are witnessing rapid industrialization. As treatments become more sophisticated, there is an emerging need for creating new treatment models that are safe as well as effective for critical patients. Furthermore, stringent regulations in terms of operation, production, and commercialization have further ensured compliance with safety measures, thus driving the demand for pyrogen testing in these markets.

Geographically, the global pyrogen testing market is cumulative for North America, Europe, Asia Pacific, the Middle East, Africa, and Latin America.

North America, followed by Europe, was the largest market for pyrogen testing in 2016, and it is expected that the region will continue to retain its dominance through the forecast period of 2017–2025. Being large and diversified, the U.S. is the largest and most critical market for pyrogen testing. The country houses several occupations, ranging from scientific research to manufacturing. The pharmaceuticals sector in the U.S. has consistently been the most research-intensive industry. However, the research and development activities performed in the U.S. are consistently being outsourced to Asian countries such as China, Singapore, and India, mainly due to increasing R&D expenses.

The detailed regional classification of the global pyrogen testing market is as follows:

  • North America (U.S. and Canada)
  • Europe (U.K., Germany, and the Rest of Europe)
  • Asia Pacific (China, Japan, and the Rest of Asia Pacific)
  • Latin America (Brazil, Mexico, and the Rest of Latin America)
  • Middle East and Africa (GCC plus the rest of the Middle East and Africa) 

Frequently Asked Questions:

The market for Pyrogen Testing Market is expected to reach US$ 1,853.3 Mn By 2025.

The Pyrogen Testing Market is expected to see significant CAGR growth over the coming years, at 12.51%.

The report is forecasted from 2017-2025.

The base year of this report is 2016.

Charles River Laboratories, Inc., Ellab A/S, GenScript, Hyglos GMBH (bioMérieux), Lonza Group, Merck KGaA (Merck Millipore), Sigma-Aldrich Corporation, Thermo Fisher Scientific, Inc., Wako Chemicals USA, Inc. (Pyrostar)are some of the major players in the global market.

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Trusted By
Godaddy
Published Date:  Sep 2017
Category:  Biotechnology
Report ID:   58672
Report Format:   PDF
Pages:   120
Rating:    4.8 (60)
Delivery Time: 24 Hours to 48 Hours   
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