Home / Press Release / Recent FDA approved CAR T Cell Therapy Products And Increasing Number Of Patients Suffering With Refractory B Cell Acute Lymphocytic Leukemia Drives The CAR T Cell Therapy Market

Recent FDA approved CAR T Cell Therapy Products And Increasing Number Of Patients Suffering With Refractory B Cell Acute Lymphocytic Leukemia Drives The CAR T Cell Therapy Market

The latest market report published by Credence Research, Inc. “CAR T Cell Therapy Market - Growth, Future Prospects, Competitive Analysis, 2018 - 2026,” the global CAR T cell therapy market is expected to expand at a CAGR of 5.96 % from 2018 to 2026.

Browse the full report CAR T Cell Therapy Market - Growth, Future Prospects, Competitive Analysis, 2018 – 2026 report at http://www.credenceresearch.com/report/car-t-cell-therapy-market

Market Insights

The diagnosis of acute lymphocytic leukemia (ALL) is very ambiguous as the symptoms overlap with Non-Hodgkin lymphoma. Due to technological advancement in the diagnostic kits acute lymphocytic lymphoma can be detected early and effective treatment can be started immediately. Flow cytometry and immunohistochemistry are useful in identifying the immunophenotyping by the proteins expressed by the cells. It is useful in determining the exact type of leukemia. Chromosome testing is being widely employed for the precise diagnosis of acute lymphocytic leukemia to accurately identify the DNA translocation between chromosome 9 and chromosome 22. World Health organization guidelines have postulated that acute lymphocytic leukemia can be prevented upto a certain extent by prohibiting the exposure to radiation, chemical, viral infection, cigarette smoking and prolonged exposure to gasoline and electromagnetic fields. The traditional approach adopted for the treatment of ALL was blood transfusion to increase the count of healthy blood cells, antibiotics used to curb the spread of infection and chemotherapy to kill the leukemia cells present in the bone marrow. CAR T cell therapy is the most hot topic discussed among oncologist throughout the globe. The FDA approved CAR T cell therapy are Axicabtagene ciloleucel (Yescarta), Tisagenleucel (Kymriah), and Tocilizumab (Actemra). During the clinical trial studies few side effects have been encountered in patients put on CAR T cell therapy are cytokine release syndrome, b-cell aplasia and tumor lysis syndrome.  

Currently CD19 antigens have been approved by USFDA for the treatment of relapsed b-cell acute lymphocytic leukemia. CD 22 and CD 30 antigens show promising result in preclinical trials for the treatment of non-Hodgkin’s lymphoma.

Recent approval of CD19 antigens as CAR T cell therapy for the treatment of b cell acute lymphocytic leukemia and increasing number of children suffering with acute lymphocytic leukemia is responsible for the dominance of ALL.  Non-Hodgkin’s lymphoma and multiple myeloma are being diligently studied by pharmaceutical players owing to their rising prevalence and lack of efficacy utilizing chemotherapy.

Rising prevalence of relapsed acute lymphocytic leukemia and technological advancement in the screening of cancer drives the North America CAR T cells therapy market. Moreover the domicile of pharmaceutical companies pioneering in CAR T cell therapy. Increasing geriatric population suffering with leukemia and government initiatives to fight cancer will result in the positive growth of CAR T cell therapy in Asia Pacific.

The major pharmaceutical players actively engaged in the CAR T cell therapy market are Bellicum Pharmaceuticals, Inc., Immune Therapeutics, Celgene Corporation, Cellectis, Kite Pharma, Eureka Therapeutics, Juno Therapeutics, Sorrento Therapeutics and Novartis AG among others.

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