Home / Pharmaceuticals / Fragment-based Drug Discovery Market By Service Type (Fragment Screening Technique, Fragment Optimization Technique), By End-User (Biopharmaceutical Companies, Contract Research Organization, Academic And Research Institutions) - Growth, Future Prospects & Competitive Analysis, 2018 – 2026

Fragment-based Drug Discovery Market By Service Type (Fragment Screening Technique, Fragment Optimization Technique), By End-User (Biopharmaceutical Companies, Contract Research Organization, Academic And Research Institutions) - Growth, Future Prospects & Competitive Analysis, 2018 – 2026

Published: Dec 2018 | Report Code: 59474-12-18

Industry Outlook

The global fragment-based drug discovery (FBDD) market held US$ 503.4 Mn in 2017 and expected to grow at compound annual growth rate (CAGR) of 11.8% during the forecast period from 2018 to 2026. Fragment-based drug discovery has emerged as a significant substitute to high throughput screening (HTS) in last two decades for the identification of lead compounds for drug discovery. Introduction of novel techniques in existing fragment-based drug discovery process has reduced time and cost of production which has led to the growing demand of fragment-based drug design. In comparison to HTS, fragment-based approach requires screening of fewer compounds and offers more efficient and productive optimization of compounds. Growing uptake of FBDD by biopharmaceutical companies with an aim of cost effectiveness and high productivity is projected to drive the fragment-based drug discovery market. Moreover, employment of fragment-based drug discovery has created demand for specialized and efficient biophysical techniques that are capable weak affinity interactions. These include nuclear magnetic resonance (NMR) spectroscopy, x-ray crystallography, and capillary electrophoresis among others. Technological advancements in these screening technologies will further drive the growth of the market. North America dominated the global fragment-based drug discovery market owing to high R&D by biopharmaceutical companies for time and cost-efficient drug discovery techniques. Asia Pacific is projected to grow at fastest growth rate during the forecast period due to number of CROs operating in the region and growing outsourcing of pharmaceutical manufacturing in Asia Pacific. 

Market Synopsis

Fragment-based Drug Discovery Market

Technological advancements to drive the Fragment-based Drug Discovery Market

In 2017, NMR spectroscopy and x-ray crystallography are the leading segments in the global fragment-based drug discovery market. NMR spectroscopy is highly productive and efficient due to recent modifications and most commonly used technique. Companies such as Abbott Laboratories, Novartis, and Roche are reported to be using NMR spectroscopy for fragment-based drug discovery. X-ray crystallography provides a detailed profile of fragment-binding and identifying crystal structures has become a high-throughput process with the help of x-ray crystallography. Moreover, x-ray crystallography is considered gold standard in orthogonal fragment screening as it confirms the binding of the protein to the target. Other techniques that are extensively used for fragment-based drug discovery is capillary electrophoresis, surface plasmon resonance, mass spectroscopy and differential scanning fluorimetry; expected to witness substantial growth during the forecast period thereby driving the fragment-based drug discovery market.

Fragment-based Drug Discovery Market

Historical & Forecast Period

2016 – Historical Year
2017 – Base Year
2018-2026 – Forecast Period

This research report presents the analysis of each segment from 2016 to 2026 considering 2017 as the base year for the research. Compounded annual growth rate (CAGR) for each respective segments calculated for the forecast period from 2018 to 2026.

Fragment-based Drug Discovery Market

Report Scope by Segments

Fragment-based Drug Discovery market report furnishes quantitative analysis along with its latest market trends. The market is segmented based on service type, end-user, and geography.

By Service Type (2016–2026; US$ Mn)

  • Fragment Screening Technique
  • NMR Spectroscopy
  • Differential Scanning Fluorimetry (DSF)
  • X-Ray Crystallography 
  • Fluorescence Polarization (FP)
  • Isothermal Titration Calorimetry (ITC)
  • Surface Plasmon Resonance (SPR)
  • Mass Spectrometry (MS)
  • Capillary Electrophoresis (CE)
  • Others
  • Fragment Optimization Technique

By End-User (2016 – 2026; Mn)

  • Biopharmaceutical Companies
  • Contract Research Organization
  • Academic and Research Institutions

Geography Segment (2016–2026; US$ Mn)

  • North America
    • U.S.
    • Canada
  • Europe
    • U.K.
    • Germany
    • Rest of Europe
  • Asia Pacific (APAC)
    • China
    • Japan
    • Rest of APAC
  • Latin America (LATAM)
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East and Africa (MEA)
    • GCC
    • Rest of Middle East and Africa

Market is studied in order to understand the current dynamics and future trends in the global fragment-based drug discovery market. The study includes market size and forecast for all considered segments presented in the report for the period from 2016 to 2026, along with respective compound annual growth rate (CAGRs) for the forecast period from 2018 to 2026, considering 2017 as the base year. The key players currently engaged in fragment-based drug discovery market include Astex Pharmaceuticals, Charles River Laboratories International, Inc., Evotec AG, Kinetic Discovery Limited, Alveus Pharmaceuticals Pvt. Ltd. Among others.

Fragment-based Drug Discovery Market

Key questions answered in this report

  • How the global fragment-based drug discovery market will perform during the forecast period from 2018 to 2026?
  • What are the latest trends in the fragment-based drug discovery market and valuable opportunities for key players?
  • Who are the leading players in the global fragment-based drug discovery market?
  • Which is the leading/and fastest region in the global fragment-based drug discovery market?
  • What are drivers and restrains governing the global fragment-based drug discovery market?

Chapter 1. Preface
1.1. Report Description
1.1.1. Study Purpose
1.1.2. Target Audience
1.1.3. USP and Key Offerings
1.2. Research Scope
1.3. Research Methodology
1.3.1. Phase I – Secondary Research
1.3.2. Phase II – Primary Research
1.3.3. Phase III – Expert Panel Review
1.3.4. Assumptions
1.4. Market Segmentation

Chapter 2. Executive Summary
2.1. Global Fragment-based Drug Discovery Market Portraiture
2.2. Global Fragment-based Drug Discovery Market, by Service Type, 2017 (US$ Mn)
2.3. Global Fragment-based Drug Discovery Market, by End-User, 2017 (US$ Mn)
2.4. Global Fragment-based Drug Discovery Market, by Geography, 2017 (US$ Mn)

Chapter 3. Fragment-based Drug Discovery: Market Dynamics and Outlook
3.1. Market Overview
3.2. Drivers
3.3. Challenges
3.4. Opportunities
3.5. Attractive Investment Proposition, by Geography, 2017
3.6. Competitive Analysis: Global Fragment-based Drug Discovery Market, by Key Players, 2017

Chapter 4. Global Fragment-based Drug Discovery Market, by Service Type, 2016-2026 (US$ Mn)
4.1. Overview
4.2. Fragment Screening Technique
4.2.1. NMR Spectroscopy
4.2.2. Differential Scanning Fluorimetry (DSF)
4.2.3. X-Ray Crystallography
4.2.4. Fluorescence Polarization (FP)
4.2.5. Isothermal Titration Calorimetry (ITC)
4.2.6. Surface Plasmon Resonance (SPR)
4.2.7. Mass Spectrometry (MS)
4.2.8. Capillary Electrophoresis (CE)
4.2.9. Others
4.3. Fragment Optimization Technique

Chapter 5. Global Fragment-based Drug Discovery Market, by End-User, 2016 – 2026 (US$ Mn)
5.1. Overview
5.2. Biopharmaceutical Companies
5.3. Contract Research Organization
5.4. Academic and Research Institutions

Chapter 6. Global Fragment-based Drug Discovery Market, by Geography, 2016 – 2026 (US$ Mn)
6.1. North America Fragment-based Drug Discovery Market Analysis, 2016 – 2026
6.1.1. North America Fragment-based Drug Discovery Market, by Service Type, 2016 - 2026 (US$ Mn)
6.1.2. North America Fragment-based Drug Discovery Market, by End-User, 2016 - 2026 (US$ Mn)
6.1.3. North America Fragment-based Drug Discovery Market, by Country, 2016 – 2026 (US$ Mn)
6.1.3.1. U.S.
6.1.3.2. Canada
6.2. Europe Fragment-based Drug Discovery Market Analysis, 2016 – 2026
6.2.1. Europe Fragment-based Drug Discovery Market, by Service Type, 2016 - 2026 (US$ Mn)
6.2.2. Europe Fragment-based Drug Discovery Market, by End-User, 2016 - 2026 (US$ Mn)
6.2.3. Europe Fragment-based Drug Discovery Market, by Country/Region, 2016 – 2026 (US$ Mn)
6.2.3.1. U.K.
6.2.3.2. Germany
6.2.3.3. Rest of Europe
6.3. Asia Pacific Fragment-based Drug Discovery Market Analysis, 2016 – 2026
6.3.1. Asia Pacific Fragment-based Drug Discovery Market, by Service Type, 2016 - 2026 (US$ Mn)
6.3.2. Asia Pacific Fragment-based Drug Discovery Market, by End-User, 2016 - 2026 (US$ Mn)
6.3.3. Asia Pacific Fragment-based Drug Discovery Market, by Country/Region, 2016 – 2026 (US$ Mn)
6.3.3.1. China
6.3.3.2. Japan
6.3.3.3. Rest of Asia Pacific
6.4. Latin America Fragment-based Drug Discovery Market Analysis, 2016 – 2026
6.4.1. Latin America Fragment-based Drug Discovery Market, by Service Type, 2016 - 2026 (US$ Mn)
6.4.2. Latin America Fragment-based Drug Discovery Market, by End-User, 2016 - 2026 (US$ Mn)
6.4.3. Latin America Fragment-based Drug Discovery Market, by Country/Region, 2016 – 2026 (US$ Mn)
6.4.3.1. Brazil
6.4.3.2. Mexico
6.4.3.3. Rest of Latin America
6.5. Middle East & Africa Fragment-based Drug Discovery Market, 2016 – 2026
6.5.1. Middle East & Africa Fragment-based Drug Discovery Market, by Service Type, 2016 - 2026 (US$ Mn)
6.5.2. Middle East & Africa Fragment-based Drug Discovery Market, by End-User, 2016 - 2026 (US$ Mn)
6.5.3. Middle East & Africa Fragment-based Drug Discovery Market, by Region, 2016 – 2026 (US$ Mn)
6.5.3.1. GCC
6.5.3.2. Rest of Middle East & Africa

Chapter 7. Company Profiles
7.1. Astex Pharmaceuticals
7.1.1. Business Description
7.1.2. Financial Information (Subject to Data Availability)
7.1.3. Product Portfolio
7.1.4. News Coverage
7.2. Alveus Pharmaceuticals Pvt. Ltd.
7.3. Beactica AB
7.4. Charles River Laboratories International, Inc.
7.5. Crown Bioscience, Inc.
7.6. Emerald BioStructures, Inc.
7.7. Evotec AG
7.8. Kinetic Discovery Limited
7.9. Proteros Fragments GmbH
7.10. Sprint Bioscience
7.11. Structure Based Design, Inc.
7.12. Sygnature Discovery

FIG 1. Fragment-based Drug Discovery Market: Research Methodology
FIG 2. Fragment-based Drug Discovery: Market Segmentation
FIG 3. Global Fragment-based Drug Discovery Market, by Service Type, 2017 (US$ Mn)
FIG 4. Global Fragment-based Drug Discovery Market, by End-User, 2017 (US$ Mn)
FIG 5. Global Fragment-based Drug Discovery Market, by Geography, 2017 (US$ Mn)
FIG 6. Attractive Investment Proposition, by Geography, 2017
FIG 7. Competitive Analysis: Global Fragment-based Drug Discovery Market, by Key Players, 2017
FIG 8. Global NMR Spectroscopy Market in Fragment-based Drug Discovery, 2016-2026 (US$ Mn)
FIG 9. Global Differential Scanning Fluorimetry (DSF) Market in Fragment-based Drug Discovery, 2016-2026(US$ Mn)
FIG 10. Global X-Ray Crystallography Market in Fragment-based Drug Discovery, 2016-2026(US$ Mn)
FIG 11. Global Fluorescence Polarization (FP) Market in Fragment-based Drug Discovery, 2016-2026(US$ Mn)
FIG 12. Global Isothermal Titration Calorimetry (ITC) Market in Fragment-based Drug Discovery, 2016-2026(US$ Mn)
FIG 13. Global Surface Plasmon Resonance (SPR) Market in Fragment-based Drug Discovery, 2016-2026(US$ Mn)
FIG 14. Global Mass Spectrometry Market in Fragment-based Drug Discovery, 2016-2026(US$ Mn)
FIG 15. Global Capillary Electrophoresis Market in Fragment-based Drug Discovery, 2016-2026(US$ Mn)
FIG 16. Global Other Services Market in Fragment-based Drug Discovery, 2016-2026(US$ Mn)
FIG 17. Global Fragment Optimization Technique Market in Fragment-based Drug Discovery, 2016-2026(US$ Mn)
FIG 18. Global Biopharmaceutical Companies End-User in Fragment-based Drug Discovery Market, 2016-2026(US$ Mn)
FIG 19. Global Contract Research Organization End-User in Fragment-based Drug Discovery Market, 2016-2026(US$ Mn)
FIG 20. Global Academic and Research Institutions End-User in Fragment-based Drug Discovery Market, 2016-2026(US$ Mn)
FIG 21. U.S. Fragment-based Drug Discovery Market, 2016-2026 (US$ Mn)
FIG 22. Canada Fragment-based Drug Discovery Market, 2016-2026 (US$ Mn)
FIG 23. U.K. Fragment-based Drug Discovery Market, 2016-2026 (US$ Mn)
FIG 24. Germany Fragment-based Drug Discovery Market, 2016-2026 (US$ Mn)
FIG 25. Rest of Europe Fragment-based Drug Discovery Market, 2016-2026 (US$ Mn)
FIG 26. China Fragment-based Drug Discovery Market, 2016-2026 (US$ Mn)
FIG 27. Japan Fragment-based Drug Discovery Market, 2016-2026 (US$ Mn)
FIG 28. Rest of Asia Pacific Fragment-based Drug Discovery Market, 2016-2026 (US$ Mn)
FIG 29. Brazil Fragment-based Drug Discovery Market, 2016-2026 (US$ Mn)
FIG 30. Mexico Fragment-based Drug Discovery Market, 2016-2026 (US$ Mn)
FIG 31. Rest of Latin America Fragment-based Drug Discovery Market, 2016-2026 (US$ Mn)
FIG 32. GCC Fragment-based Drug Discovery Market, 2016-2026 (US$ Mn)
FIG 33. Rest of Middle East & Africa Fragment-based Drug Discovery Market, 2016-2026 (US$ Mn)

TABLE 1 Global Fragment-based Drug Discovery Market Portraiture
TABLE 2 Global Fragment-based Drug Discovery Market, by Service Type, 2016 – 2026 (US$ Mn)
TABLE 3 Global Fragment Screening Technique Market, by Type, 2016 – 2026 (US$ Mn)
TABLE 4 Global Fragment-based Drug Discovery Market, by End-User, 2016 – 2026 (US$ Mn)
TABLE 5 Global Fragment-based Drug Discovery Market, by Geography, 2016 – 2026 (US$ Mn)
TABLE 6 North America Fragment-based Drug Discovery Market, by Service Type, 2016 – 2026 (US$ Mn)
TABLE 7 North America Fragment-based Drug Discovery Market, by End-User, 2016 – 2026 (US$ Mn)
TABLE 8 North America Fragment-based Drug Discovery Market, by Country, 2016 – 2026 (US$ Mn)
TABLE 9 Europe Fragment-based Drug Discovery Market, by Service Type, 2016 – 2026 (US$ Mn)
TABLE 10 Europe Fragment-based Drug Discovery Market, by End-User, 2016 – 2026 (US$ Mn)
TABLE 11 Europe Fragment-based Drug Discovery Market, by Country/Region, 2016 – 2026 (US$ Mn)
TABLE 12 Asia Pacific Fragment-based Drug Discovery Market, by Service Type, 2016 – 2026 (US$ Mn)
TABLE 13 Asia Pacific Fragment-based Drug Discovery Market, by End-User, 2016 – 2026 (US$ Mn)
TABLE 14 Asia Pacific Fragment-based Drug Discovery Market, by Country/Region, 2016 – 2026 (US$ Mn)
TABLE 15 Latin America Fragment-based Drug Discovery Market, by Service Type, 2016 – 2026 (US$ Mn)
TABLE 16 Latin America Fragment-based Drug Discovery Market, by End-User, 2016 – 2026 (US$ Mn)
TABLE 17 Latin America Fragment-based Drug Discovery Market, by Country/Region, 2016 – 2026 (US$ Mn)
TABLE 18 Middle East & Africa Fragment-based Drug Discovery Market, by Service Type, 2016 – 2026 (US$ Mn)
TABLE 19 Middle East & Africa Fragment-based Drug Discovery Market, by End-User, 2016 – 2026 (US$ Mn)
TABLE 20 Middle East & Africa Fragment-based Drug Discovery Market, by Region, 2016 – 2026 (US$ Mn)
TABLE 21 Astex Pharmaceuticals: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 22 Alveus Pharmaceuticals Pvt. Ltd.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 23 Beactica AB: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 24 Charles River Laboratories International, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 25 Crown Bioscience, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 26 Emerald BioStructures, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 27 Evotec AG: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 28 Kinetic Discovery Limited: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 29 Proteros Fragments GmbH: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 30 Sprint Bioscience: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 31 Structure Based Design, Inc.: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)
TABLE 32 Sygnature Discovery: Company Snapshot (Business Description; Financial Information; Product Portfolio; Key Developments)

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